| UniProt: | P37655 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12261 | ||
| Length: | 250 (239) | ||
| Sequences: | 8981 | ||
| Seq/Len: | 37.58 |
| BCSQ
Paralog alert: 0.85 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: BCSQ MIND |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 19_T | 122_L | 4.375 | 1.00 | |
| 80_D | 118_Y | 4.197 | 1.00 | |
| 200_H | 227_E | 3.898 | 1.00 | |
| 29_L | 233_N | 3.416 | 1.00 | |
| 18_I | 228_I | 3.249 | 1.00 | |
| 5_G | 140_C | 3.081 | 1.00 | |
| 26_L | 120_W | 3.008 | 1.00 | |
| 31_E | 120_W | 2.851 | 1.00 | |
| 214_P | 217_E | 2.71 | 1.00 | |
| 34_L | 118_Y | 2.675 | 1.00 | |
| 28_M | 229_L | 2.665 | 1.00 | |
| 148_N | 172_D | 2.501 | 1.00 | |
| 19_T | 35_V | 2.454 | 1.00 | |
| 35_V | 44_L | 2.446 | 1.00 | |
| 2_A | 142_H | 2.43 | 1.00 | |
| 172_D | 201_R | 2.226 | 1.00 | |
| 6_L | 22_L | 2.213 | 1.00 | |
| 20_A | 44_L | 2.204 | 1.00 | |
| 18_I | 169_L | 2.133 | 1.00 | |
| 185_Q | 189_Q | 2.116 | 1.00 | |
| 197_M | 234_W | 2.07 | 1.00 | |
| 32_N | 119_Q | 2.066 | 1.00 | |
| 169_L | 231_L | 2.011 | 1.00 | |
| 74_R | 80_D | 1.979 | 1.00 | |
| 23_A | 35_V | 1.944 | 1.00 | |
| 26_L | 122_L | 1.909 | 1.00 | |
| 23_A | 122_L | 1.888 | 1.00 | |
| 25_S | 232_A | 1.872 | 1.00 | |
| 29_L | 229_L | 1.835 | 1.00 | |
| 197_M | 231_L | 1.814 | 1.00 | |
| 204_A | 207_E | 1.798 | 1.00 | |
| 22_L | 232_A | 1.715 | 1.00 | |
| 25_S | 216_G | 1.694 | 1.00 | |
| 47_S | 152_N | 1.677 | 1.00 | |
| 22_L | 235_C | 1.644 | 1.00 | |
| 174_R | 201_R | 1.638 | 1.00 | |
| 20_A | 47_S | 1.638 | 1.00 | |
| 222_A | 225_A | 1.637 | 1.00 | |
| 31_E | 119_Q | 1.575 | 1.00 | |
| 69_R | 117_R | 1.562 | 1.00 | |
| 46_L | 155_I | 1.558 | 1.00 | |
| 6_L | 144_L | 1.555 | 1.00 | |
| 18_I | 171_N | 1.529 | 1.00 | |
| 6_L | 19_T | 1.524 | 1.00 | |
| 23_A | 44_L | 1.517 | 1.00 | |
| 196_P | 234_W | 1.507 | 1.00 | |
| 170_I | 184_Y | 1.49 | 1.00 | |
| 5_G | 125_L | 1.477 | 1.00 | |
| 226_E | 229_L | 1.473 | 1.00 | |
| 27_Q | 78_Q | 1.45 | 1.00 | |
| 48_F | 79_L | 1.446 | 1.00 | |
| 57_G | 60_R | 1.393 | 0.99 | |
| 27_Q | 79_L | 1.389 | 0.99 | |
| 31_E | 236_L | 1.377 | 0.99 | |
| 207_E | 211_A | 1.36 | 0.99 | |
| 14_G | 171_N | 1.358 | 0.99 | |
| 219_R | 222_A | 1.355 | 0.99 | |
| 29_L | 236_L | 1.351 | 0.99 | |
| 186_L | 189_Q | 1.329 | 0.99 | |
| 3_V | 123_I | 1.326 | 0.99 | |
| 230_T | 233_N | 1.323 | 0.99 | |
| 67_D | 70_D | 1.313 | 0.99 | |
| 142_H | 166_A | 1.309 | 0.99 | |
| 142_H | 167_H | 1.301 | 0.99 | |
| 80_D | 116_G | 1.282 | 0.99 | |
| 34_L | 121_I | 1.282 | 0.99 | |
| 68_W | 82_L | 1.265 | 0.99 | |
| 38_A | 123_I | 1.257 | 0.99 | |
| 213_Q | 217_E | 1.251 | 0.99 | |
| 43_L | 156_R | 1.247 | 0.99 | |
| 43_L | 152_N | 1.24 | 0.98 | |
| 144_L | 169_L | 1.234 | 0.98 | |
| 205_M | 224_A | 1.234 | 0.98 | |
| 58_W | 61_A | 1.233 | 0.98 | |
| 2_A | 141_D | 1.232 | 0.98 | |
| 173_F | 198_L | 1.226 | 0.98 | |
| 233_N | 237_L | 1.221 | 0.98 | |
| 152_N | 209_L | 1.214 | 0.98 | |
| 38_A | 136_L | 1.199 | 0.98 | |
| 81_L | 86_Q | 1.198 | 0.98 | |
| 184_Y | 198_L | 1.197 | 0.98 | |
| 50_V | 81_L | 1.193 | 0.98 | |
| 202_D | 224_A | 1.177 | 0.98 | |
| 20_A | 48_F | 1.167 | 0.97 | |
| 56_Q | 60_R | 1.166 | 0.97 | |
| 106_C | 110_Q | 1.165 | 0.97 | |
| 149_V | 170_I | 1.165 | 0.97 | |
| 7_Q | 125_L | 1.164 | 0.97 | |
| 223_L | 226_E | 1.155 | 0.97 | |
| 26_L | 33_V | 1.155 | 0.97 | |
| 179_V | 183_I | 1.141 | 0.97 | |
| 231_L | 235_C | 1.14 | 0.97 | |
| 220_S | 225_A | 1.12 | 0.96 | |
| 177_S | 180_Q | 1.109 | 0.96 | |
| 3_V | 121_I | 1.107 | 0.96 | |
| 150_D | 153_C | 1.105 | 0.96 | |
| 110_Q | 113_K | 1.101 | 0.96 | |
| 171_N | 228_I | 1.099 | 0.96 | |
| 202_D | 222_A | 1.093 | 0.96 | |
| 203_E | 207_E | 1.09 | 0.96 | |
| 186_L | 190_S | 1.085 | 0.96 | |
| 227_E | 230_T | 1.081 | 0.95 | |
| 36_V | 121_I | 1.078 | 0.95 | |
| 26_L | 232_A | 1.074 | 0.95 | |
| 18_I | 22_L | 1.067 | 0.95 | |
| 114_A | 117_R | 1.059 | 0.95 | |
| 6_L | 18_I | 1.056 | 0.95 | |
| 107_S | 111_Q | 1.055 | 0.95 | |
| 32_N | 117_R | 1.054 | 0.95 | |
| 38_A | 58_W | 1.053 | 0.95 | |
| 33_V | 119_Q | 1.048 | 0.94 | |
| 10_R | 15_T | 1.044 | 0.94 | |
| 72_G | 80_D | 1.032 | 0.94 | |
| 195_L | 198_L | 1.03 | 0.94 | |
| 230_T | 234_W | 1.027 | 0.94 | |
| 158_H | 190_S | 1.021 | 0.93 | |
| 184_Y | 188_L | 1.014 | 0.93 | |
| 204_A | 219_R | 1.014 | 0.93 | |
| 6_L | 122_L | 1.009 | 0.93 | |
| 199_I | 227_E | 1.003 | 0.93 | |
| 23_A | 79_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pg5A | 4 | 1 | 100 | 0.252 | Contact Map | 0.736 |
| 1wcv1 | 1 | 0.952 | 100 | 0.26 | Contact Map | 0.796 |
| 1g3qA | 1 | 0.904 | 100 | 0.275 | Contact Map | 0.808 |
| 1hyqA | 1 | 0.948 | 100 | 0.279 | Contact Map | 0.77 |
| 3ez9A | 2 | 0.972 | 100 | 0.287 | Contact Map | 0.613 |
| 3ez2A | 2 | 0.964 | 100 | 0.289 | Contact Map | 0.681 |
| 3ea0A | 2 | 0.892 | 100 | 0.293 | Contact Map | 0.817 |
| 3kjhA | 1 | 0.912 | 100 | 0.293 | Contact Map | 0.565 |
| 2ozeA | 1 | 0.964 | 100 | 0.296 | Contact Map | 0.603 |
| 3endA | 2 | 0.936 | 100 | 0.299 | Contact Map | 0.712 |
Sequence Conservation (Image Generated using WebLogo v3)