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OPENSEQ.org

MIND - Septum site-determining protein MinD
UniProt: P0AEZ3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10597
Length: 270 (248)
Sequences: 8928
Seq/Len: 36.00

MIND
Paralog alert: 0.85 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: BCSQ MIND
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
20_S 118_V 4.412 1.00
84_Y 114_F 4.367 1.00
212_P 238_A 4.143 1.00
30_K 244_E 3.623 1.00
19_S 239_Y 3.588 1.00
6_V 136_A 3.41 1.00
27_L 116_F 3.027 1.00
32_K 116_F 2.864 1.00
29_Q 240_A 2.802 1.00
226_P 229_L 2.721 1.00
3_R 138_E 2.672 1.00
36_V 46_L 2.641 1.00
35_V 114_F 2.57 1.00
182_R 213_E 2.426 1.00
20_S 36_V 2.42 1.00
144_N 182_R 2.372 1.00
21_A 46_L 2.367 1.00
7_V 23_I 2.305 1.00
179_L 242_T 2.164 1.00
209_G 245_R 2.099 1.00
197_E 201_E 2.085 1.00
24_A 36_V 2.059 1.00
216_S 219_R 2.056 1.00
19_S 179_L 2.035 1.00
209_G 242_T 2.027 1.00
26_G 243_V 2.005 1.00
24_A 118_V 1.956 1.00
30_K 240_A 1.941 1.00
33_K 115_E 1.939 1.00
27_L 118_V 1.92 1.00
71_N 113_D 1.904 1.00
23_I 243_V 1.901 1.00
49_I 148_S 1.797 1.00
23_I 246_L 1.763 1.00
21_A 49_I 1.693 1.00
24_A 46_L 1.658 1.00
7_V 140_I 1.642 1.00
233_A 236_G 1.629 1.00
7_V 20_S 1.629 1.00
26_G 228_I 1.613 1.00
48_L 151_R 1.604 1.00
187_R 190_R 1.604 1.00
237_K 240_A 1.567 1.00
28_A 82_N 1.559 1.00
32_K 115_E 1.552 1.00
184_N 213_E 1.502 1.00
6_V 121_S 1.476 1.00
28_A 83_L 1.463 1.00
197_E 210_V 1.462 1.00
52_C 85_I 1.462 1.00
69_T 72_Q 1.455 1.00
19_S 181_T 1.424 1.00
50_M 83_L 1.418 1.00
70_L 86_L 1.416 1.00
45_N 152_D 1.406 0.99
140_I 179_L 1.398 0.99
208_V 245_R 1.389 0.99
180_L 194_L 1.374 0.99
76_K 84_Y 1.369 0.99
59_D 62_N 1.362 0.99
198_D 201_E 1.358 0.99
15_G 181_T 1.357 0.99
4_I 119_C 1.357 0.99
39_F 119_C 1.355 0.99
138_E 177_H 1.348 0.99
84_Y 112_M 1.344 0.99
30_K 247_L 1.338 0.99
244_E 248_G 1.335 0.99
183_Y 210_V 1.31 0.99
207_L 210_V 1.305 0.99
219_R 223_Q 1.296 0.99
32_K 247_L 1.286 0.99
225_E 229_L 1.264 0.99
21_A 50_M 1.253 0.99
216_S 230_D 1.245 0.98
148_S 221_S 1.24 0.98
145_P 180_L 1.227 0.98
241_D 244_E 1.215 0.98
158_G 161_A 1.21 0.98
198_D 202_I 1.209 0.98
63_V 73_A 1.209 0.98
214_D 235_A 1.208 0.98
231_I 236_G 1.2 0.98
3_R 137_D 1.19 0.98
146_E 149_S 1.189 0.98
217_V 235_A 1.188 0.98
85_I 90_Q 1.182 0.98
138_E 176_E 1.18 0.98
181_T 239_Y 1.179 0.98
241_D 245_R 1.172 0.98
215_Q 219_R 1.172 0.98
234_D 237_K 1.165 0.97
142_T 181_T 1.159 0.97
39_F 132_A 1.156 0.97
139_A 160_L 1.147 0.97
2_A 110_K 1.138 0.97
35_V 117_I 1.136 0.97
45_N 148_S 1.134 0.97
26_G 240_A 1.131 0.97
230_D 233_A 1.123 0.97
103_A 107_D 1.11 0.96
211_I 235_A 1.104 0.96
27_L 34_T 1.102 0.96
90_Q 155_R 1.097 0.96
116_F 247_L 1.094 0.96
154_D 202_I 1.088 0.96
78_K 84_Y 1.082 0.96
33_K 113_D 1.082 0.96
7_V 118_V 1.079 0.95
4_I 117_I 1.079 0.95
107_D 110_K 1.064 0.95
242_T 246_L 1.06 0.95
11_K 16_K 1.059 0.95
8_T 121_S 1.052 0.95
232_N 237_K 1.046 0.94
42_G 128_G 1.04 0.94
237_K 241_D 1.038 0.94
34_T 115_E 1.036 0.94
24_A 83_L 1.034 0.94
110_K 137_D 1.032 0.94
9_S 14_V 1.022 0.93
74_L 84_Y 1.02 0.93
2_A 117_I 1.02 0.93
144_N 149_S 1.018 0.93
22_A 25_T 1.011 0.93
199_V 203_L 1.005 0.93
14_V 149_S 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1hyqA10.9371000.261Contact Map0.753
3q9lA20.9631000.282Contact Map0.825
1g3qA10.87041000.292Contact Map0.793
1wcv110.91481000.294Contact Map0.761
3pg5A40.95191000.297Contact Map0.72
3ea0A20.86671000.3Contact Map0.794
3endA20.92221000.306Contact Map0.709
3ez2A20.92221000.314Contact Map0.676
3ez9A20.92961000.317Contact Map0.596
2ynmA20.92221000.321Contact Map0.716

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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