| UniProt: | P36667 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11986 | ||
| Length: | 264 (243) | ||
| Sequences: | 9747 | ||
| Seq/Len: | 40.11 |
| WBBL
Paralog alert: 0.76 [within 20: 0.24] - ratio of genomes with paralogs Cluster includes: WBBL WCAA WCAE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 176_F | 180_V | 4.368 | 1.00 | |
| 12_E | 41_L | 3.067 | 1.00 | |
| 35_D | 56_S | 2.911 | 1.00 | |
| 3_Y | 82_D | 2.704 | 1.00 | |
| 30_K | 53_D | 2.657 | 1.00 | |
| 8_S | 42_L | 2.645 | 1.00 | |
| 178_D | 207_V | 2.636 | 1.00 | |
| 197_D | 201_R | 2.629 | 1.00 | |
| 101_T | 214_A | 2.551 | 1.00 | |
| 57_G | 68_I | 2.484 | 1.00 | |
| 3_Y | 30_K | 2.338 | 1.00 | |
| 34_R | 69_A | 2.319 | 1.00 | |
| 11_H | 90_P | 2.308 | 1.00 | |
| 16_K | 20_E | 2.264 | 1.00 | |
| 105_Y | 212_V | 2.237 | 1.00 | |
| 97_D | 101_T | 2.223 | 1.00 | |
| 5_I | 69_A | 2.221 | 1.00 | |
| 86_L | 173_L | 2.185 | 1.00 | |
| 10_G | 39_S | 2.143 | 1.00 | |
| 84_Y | 106_V | 2.136 | 1.00 | |
| 84_Y | 173_L | 2.095 | 1.00 | |
| 181_R | 205_A | 1.999 | 1.00 | |
| 68_I | 72_Y | 1.998 | 1.00 | |
| 30_K | 82_D | 1.972 | 1.00 | |
| 70_V | 85_I | 1.954 | 1.00 | |
| 2_V | 103_I | 1.918 | 1.00 | |
| 70_V | 179_F | 1.89 | 1.00 | |
| 10_G | 38_D | 1.884 | 1.00 | |
| 66_N | 89_N | 1.876 | 1.00 | |
| 177_S | 181_R | 1.871 | 1.00 | |
| 113_F | 202_L | 1.869 | 1.00 | |
| 102_Y | 173_L | 1.855 | 1.00 | |
| 178_D | 202_L | 1.849 | 1.00 | |
| 35_D | 38_D | 1.838 | 1.00 | |
| 41_L | 44_Q | 1.836 | 1.00 | |
| 106_V | 173_L | 1.832 | 1.00 | |
| 53_D | 72_Y | 1.818 | 1.00 | |
| 21_N | 94_M | 1.795 | 1.00 | |
| 111_Y | 210_H | 1.762 | 1.00 | |
| 12_E | 45_I | 1.76 | 1.00 | |
| 163_V | 208_R | 1.759 | 1.00 | |
| 101_T | 104_K | 1.7 | 1.00 | |
| 9_H | 60_Y | 1.696 | 1.00 | |
| 55_I | 68_I | 1.667 | 1.00 | |
| 112_A | 207_V | 1.655 | 1.00 | |
| 94_M | 98_D | 1.633 | 1.00 | |
| 110_R | 208_R | 1.625 | 1.00 | |
| 17_K | 93_I | 1.623 | 1.00 | |
| 86_L | 98_D | 1.615 | 1.00 | |
| 6_I | 18_L | 1.612 | 1.00 | |
| 3_Y | 73_V | 1.584 | 1.00 | |
| 43_K | 56_S | 1.569 | 1.00 | |
| 68_I | 71_A | 1.568 | 1.00 | |
| 86_L | 99_L | 1.558 | 1.00 | |
| 66_N | 87_F | 1.548 | 1.00 | |
| 177_S | 180_V | 1.525 | 1.00 | |
| 181_R | 207_V | 1.515 | 1.00 | |
| 55_I | 72_Y | 1.512 | 1.00 | |
| 64_H | 187_Q | 1.507 | 1.00 | |
| 73_V | 82_D | 1.505 | 1.00 | |
| 17_K | 220_Y | 1.49 | 1.00 | |
| 100_L | 104_K | 1.449 | 1.00 | |
| 7_V | 65_N | 1.437 | 1.00 | |
| 16_K | 48_H | 1.434 | 1.00 | |
| 95_K | 218_I | 1.426 | 1.00 | |
| 113_F | 209_L | 1.393 | 0.99 | |
| 23_N | 51_G | 1.365 | 0.99 | |
| 8_S | 90_P | 1.35 | 0.99 | |
| 105_Y | 210_H | 1.343 | 0.99 | |
| 175_R | 178_D | 1.331 | 0.99 | |
| 57_G | 65_N | 1.321 | 0.99 | |
| 5_I | 34_R | 1.319 | 0.99 | |
| 118_L | 170_S | 1.308 | 0.99 | |
| 62_F | 89_N | 1.304 | 0.99 | |
| 63_G | 194_E | 1.302 | 0.99 | |
| 20_E | 49_Y | 1.296 | 0.99 | |
| 182_V | 202_L | 1.287 | 0.99 | |
| 8_S | 33_V | 1.287 | 0.99 | |
| 21_N | 93_I | 1.286 | 0.99 | |
| 26_D | 29_Y | 1.278 | 0.99 | |
| 43_K | 54_Y | 1.277 | 0.99 | |
| 85_I | 176_F | 1.268 | 0.99 | |
| 3_Y | 32_I | 1.255 | 0.99 | |
| 87_F | 185_F | 1.249 | 0.99 | |
| 62_F | 66_N | 1.245 | 0.98 | |
| 108_S | 111_Y | 1.244 | 0.98 | |
| 84_Y | 103_I | 1.241 | 0.98 | |
| 26_D | 103_I | 1.238 | 0.98 | |
| 36_N | 65_N | 1.236 | 0.98 | |
| 57_G | 64_H | 1.23 | 0.98 | |
| 186_D | 197_D | 1.23 | 0.98 | |
| 2_V | 99_L | 1.221 | 0.98 | |
| 11_H | 14_Y | 1.217 | 0.98 | |
| 8_S | 11_H | 1.204 | 0.98 | |
| 70_V | 73_V | 1.204 | 0.98 | |
| 36_N | 57_G | 1.191 | 0.98 | |
| 46_C | 54_Y | 1.183 | 0.98 | |
| 116_L | 171_F | 1.179 | 0.98 | |
| 67_N | 187_Q | 1.177 | 0.98 | |
| 115_T | 167_C | 1.164 | 0.97 | |
| 179_F | 198_L | 1.141 | 0.97 | |
| 62_F | 194_E | 1.136 | 0.97 | |
| 20_E | 24_A | 1.133 | 0.97 | |
| 73_V | 176_F | 1.131 | 0.97 | |
| 24_A | 96_H | 1.131 | 0.97 | |
| 19_L | 31_I | 1.113 | 0.96 | |
| 105_Y | 108_S | 1.095 | 0.96 | |
| 98_D | 102_Y | 1.093 | 0.96 | |
| 16_K | 45_I | 1.09 | 0.96 | |
| 31_I | 52_L | 1.088 | 0.96 | |
| 97_D | 100_L | 1.075 | 0.95 | |
| 25_D | 100_L | 1.075 | 0.95 | |
| 62_F | 169_G | 1.072 | 0.95 | |
| 20_E | 23_N | 1.065 | 0.95 | |
| 43_K | 47_Q | 1.056 | 0.95 | |
| 95_K | 216_H | 1.055 | 0.95 | |
| 88_L | 94_M | 1.054 | 0.95 | |
| 32_I | 69_A | 1.053 | 0.95 | |
| 6_I | 22_L | 1.048 | 0.94 | |
| 6_I | 31_I | 1.048 | 0.94 | |
| 108_S | 208_R | 1.046 | 0.94 | |
| 30_K | 81_D | 1.044 | 0.94 | |
| 4_I | 86_L | 1.04 | 0.94 | |
| 179_F | 184_G | 1.029 | 0.94 | |
| 4_I | 22_L | 1.027 | 0.94 | |
| 36_N | 60_Y | 1.022 | 0.93 | |
| 112_A | 175_R | 1.015 | 0.93 | |
| 29_Y | 99_L | 1.013 | 0.93 | |
| 85_I | 179_F | 1.008 | 0.93 | |
| 34_R | 65_N | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4fixA | 2 | 0.9773 | 100 | 0.299 | Contact Map | 0.761 |
| 2ffuA | 1 | 0.9621 | 100 | 0.315 | Contact Map | 0.763 |
| 1xhbA | 1 | 0.9583 | 100 | 0.318 | Contact Map | 0.739 |
| 2d7iA | 1 | 0.9697 | 100 | 0.33 | Contact Map | 0.781 |
| 2z86A | 4 | 0.8788 | 100 | 0.338 | Contact Map | 0.859 |
| 4hg6A | 1 | 0.9318 | 100 | 0.341 | Contact Map | 0.558 |
| 3bcvA | 2 | 0.8333 | 100 | 0.346 | Contact Map | 0.819 |
| 3l7iA | 4 | 0.8977 | 100 | 0.357 | Contact Map | |
| 1qg8A | 1 | 0.8712 | 100 | 0.363 | Contact Map | 0.805 |
| 3ckjA | 1 | 0.9129 | 100 | 0.418 | Contact Map | 0.614 |
Sequence Conservation (Image Generated using WebLogo v3)