| UniProt: | P77414 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13569 | ||
| Length: | 279 (236) | ||
| Sequences: | 3295 | ||
| Seq/Len: | 13.96 |
| WCAA
Paralog alert: 0.58 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: WBBL WCAA WCAE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 164_A | 168_K | 3.875 | 1.00 | |
| 31_D | 104_S | 3.453 | 1.00 | |
| 13_T | 46_S | 3.452 | 1.00 | |
| 105_V | 200_E | 3.44 | 1.00 | |
| 41_D | 66_H | 2.852 | 1.00 | |
| 11_M | 37_M | 2.779 | 1.00 | |
| 16_R | 94_D | 2.629 | 1.00 | |
| 8_S | 86_G | 2.561 | 1.00 | |
| 67_N | 79_Q | 2.396 | 1.00 | |
| 25_K | 53_Y | 2.39 | 1.00 | |
| 15_N | 45_T | 2.376 | 1.00 | |
| 67_N | 71_S | 2.371 | 1.00 | |
| 101_N | 105_V | 2.357 | 1.00 | |
| 11_M | 23_A | 2.328 | 1.00 | |
| 21_I | 25_K | 2.258 | 1.00 | |
| 40_V | 80_A | 2.217 | 1.00 | |
| 183_D | 187_R | 2.199 | 1.00 | |
| 7_I | 107_L | 2.179 | 1.00 | |
| 36_E | 63_T | 2.174 | 1.00 | |
| 13_T | 16_R | 2.148 | 1.00 | |
| 8_S | 36_E | 2.145 | 1.00 | |
| 71_S | 75_A | 2.066 | 1.00 | |
| 102_R | 106_F | 2.054 | 1.00 | |
| 173_D | 230_K | 2.032 | 1.00 | |
| 36_E | 86_G | 2.032 | 1.00 | |
| 98_W | 102_R | 2.029 | 1.00 | |
| 21_I | 52_Q | 1.986 | 1.00 | |
| 15_N | 44_S | 1.966 | 1.00 | |
| 32_Y | 107_L | 1.936 | 1.00 | |
| 22_R | 206_H | 1.929 | 1.00 | |
| 81_I | 167_F | 1.928 | 1.00 | |
| 10_Y | 80_A | 1.906 | 1.00 | |
| 47_W | 64_Y | 1.846 | 1.00 | |
| 79_Q | 83_L | 1.814 | 1.00 | |
| 47_W | 66_H | 1.812 | 1.00 | |
| 81_I | 89_I | 1.799 | 1.00 | |
| 99_T | 204_I | 1.761 | 1.00 | |
| 88_Y | 110_K | 1.747 | 1.00 | |
| 63_T | 83_L | 1.74 | 1.00 | |
| 50_L | 64_Y | 1.735 | 1.00 | |
| 22_R | 97_E | 1.708 | 1.00 | |
| 73_A | 180_Q | 1.678 | 1.00 | |
| 24_I | 37_M | 1.669 | 1.00 | |
| 65_I | 83_L | 1.643 | 1.00 | |
| 21_I | 49_Q | 1.636 | 1.00 | |
| 41_D | 44_S | 1.625 | 1.00 | |
| 77_R | 93_D | 1.623 | 1.00 | |
| 77_R | 91_G | 1.606 | 1.00 | |
| 11_M | 27_V | 1.561 | 1.00 | |
| 125_V | 129_E | 1.532 | 1.00 | |
| 67_N | 75_A | 1.503 | 1.00 | |
| 14_W | 70_N | 1.487 | 1.00 | |
| 75_A | 174_T | 1.483 | 1.00 | |
| 169_E | 191_E | 1.48 | 1.00 | |
| 166_R | 188_M | 1.479 | 1.00 | |
| 24_I | 53_Y | 1.46 | 1.00 | |
| 170_C | 188_M | 1.46 | 1.00 | |
| 51_Q | 66_H | 1.453 | 1.00 | |
| 65_I | 79_Q | 1.448 | 1.00 | |
| 74_C | 180_Q | 1.447 | 1.00 | |
| 90_T | 98_W | 1.444 | 1.00 | |
| 104_S | 108_A | 1.442 | 1.00 | |
| 24_I | 28_L | 1.441 | 1.00 | |
| 20_A | 50_L | 1.44 | 1.00 | |
| 7_I | 103_L | 1.436 | 1.00 | |
| 35_W | 103_L | 1.43 | 1.00 | |
| 39_I | 50_L | 1.41 | 1.00 | |
| 67_N | 76_V | 1.391 | 0.99 | |
| 47_W | 51_Q | 1.38 | 0.99 | |
| 27_V | 92_I | 1.356 | 0.99 | |
| 6_L | 87_E | 1.333 | 0.99 | |
| 23_A | 92_I | 1.318 | 0.99 | |
| 25_K | 29_R | 1.308 | 0.99 | |
| 36_E | 85_Q | 1.306 | 0.99 | |
| 109_H | 198_V | 1.296 | 0.99 | |
| 6_L | 34_N | 1.283 | 0.99 | |
| 17_Q | 49_Q | 1.277 | 0.99 | |
| 8_S | 84_A | 1.256 | 0.99 | |
| 173_D | 183_D | 1.254 | 0.99 | |
| 79_Q | 82_M | 1.245 | 0.98 | |
| 13_T | 94_D | 1.239 | 0.98 | |
| 106_F | 161_F | 1.226 | 0.98 | |
| 87_E | 163_W | 1.204 | 0.98 | |
| 90_T | 103_L | 1.203 | 0.98 | |
| 16_R | 19_L | 1.19 | 0.98 | |
| 89_I | 164_A | 1.165 | 0.97 | |
| 42_D | 93_D | 1.164 | 0.97 | |
| 20_A | 46_S | 1.157 | 0.97 | |
| 27_V | 37_M | 1.151 | 0.97 | |
| 87_E | 165_W | 1.137 | 0.97 | |
| 25_K | 28_L | 1.135 | 0.97 | |
| 29_R | 100_P | 1.132 | 0.97 | |
| 90_T | 161_F | 1.131 | 0.97 | |
| 42_D | 70_N | 1.129 | 0.97 | |
| 108_A | 112_Q | 1.125 | 0.97 | |
| 110_K | 161_F | 1.115 | 0.96 | |
| 101_N | 104_S | 1.106 | 0.96 | |
| 91_G | 172_F | 1.103 | 0.96 | |
| 12_P | 77_R | 1.098 | 0.96 | |
| 167_F | 184_I | 1.093 | 0.96 | |
| 84_A | 164_A | 1.091 | 0.96 | |
| 12_P | 93_D | 1.089 | 0.96 | |
| 31_D | 101_N | 1.067 | 0.95 | |
| 9_I | 90_T | 1.059 | 0.95 | |
| 9_I | 35_W | 1.054 | 0.95 | |
| 73_A | 213_Q | 1.054 | 0.95 | |
| 49_Q | 53_Y | 1.051 | 0.94 | |
| 165_W | 169_E | 1.04 | 0.94 | |
| 73_A | 77_R | 1.035 | 0.94 | |
| 81_I | 84_A | 1.033 | 0.94 | |
| 160_V | 185_F | 1.026 | 0.94 | |
| 28_L | 53_Y | 1.011 | 0.93 | |
| 165_W | 168_K | 1.003 | 0.93 | |
| 154_N | 182_Y | 1.002 | 0.92 | |
| 24_I | 50_L | 1.001 | 0.92 | |
| 43_C | 67_N | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2z86A | 4 | 0.8925 | 100 | 0.378 | Contact Map | 0.848 |
| 3bcvA | 2 | 0.7778 | 100 | 0.384 | Contact Map | 0.832 |
| 3l7iA | 4 | 0.9642 | 100 | 0.392 | Contact Map | |
| 1qg8A | 1 | 0.828 | 100 | 0.406 | Contact Map | 0.779 |
| 4fixA | 2 | 0.9606 | 100 | 0.435 | Contact Map | 0.698 |
| 2d7iA | 1 | 0.9785 | 100 | 0.45 | Contact Map | 0.753 |
| 1xhbA | 1 | 0.9821 | 100 | 0.456 | Contact Map | 0.711 |
| 2ffuA | 1 | 0.9713 | 100 | 0.476 | Contact Map | 0.725 |
| 3ckjA | 1 | 0.9534 | 100 | 0.492 | Contact Map | 0.594 |
| 4hg6A | 1 | 0.9749 | 100 | 0.5 | Contact Map | 0.471 |
Sequence Conservation (Image Generated using WebLogo v3)