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YJFC - Uncharacterized protein YjfC
UniProt: P33222 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11812
Length: 387 (386)
Sequences: 436
Seq/Len: 1.13
YJFC
Paralog alert: 0.50 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: YGIC YJFC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_T 354_S 3.357 1.00
54_A 361_A 3.211 1.00
52_P 112_V 2.691 1.00
311_N 327_G 2.634 1.00
173_Y 204_I 2.548 1.00
66_R 274_F 2.334 0.99
57_H 117_Y 2.19 0.98
42_L 46_E 2.173 0.98
314_I 339_F 2.163 0.98
344_R 347_D 2.128 0.98
77_L 266_G 2.078 0.97
2_L 39_R 2.033 0.97
128_S 155_I 1.986 0.96
71_E 88_A 1.896 0.95
154_A 158_R 1.891 0.95
52_P 280_N 1.887 0.95
8_V 13_D 1.861 0.94
268_M 284_S 1.818 0.93
269_P 286_F 1.802 0.93
100_G 117_Y 1.786 0.92
178_Q 207_E 1.775 0.92
40_F 45_I 1.759 0.91
175_C 206_I 1.718 0.90
330_A 333_P 1.698 0.89
166_L 172_F 1.689 0.89
204_I 208_D 1.687 0.89
191_Q 203_F 1.676 0.89
158_R 362_C 1.621 0.86
270_L 274_F 1.611 0.86
98_L 190_L 1.607 0.86
300_V 314_I 1.605 0.86
191_Q 201_S 1.561 0.83
344_R 349_Y 1.551 0.83
27_D 377_T 1.54 0.82
255_E 259_K 1.519 0.81
208_D 220_L 1.49 0.79
301_R 313_T 1.486 0.79
63_V 274_F 1.475 0.78
63_V 270_L 1.451 0.77
352_I 364_M 1.44 0.76
311_N 329_Y 1.437 0.76
192_D 196_Q 1.413 0.74
238_M 260_S 1.387 0.72
269_P 335_I 1.384 0.72
176_C 203_F 1.38 0.71
56_L 102_M 1.374 0.71
53_T 104_F 1.366 0.70
150_D 385_I 1.361 0.70
51_K 312_V 1.35 0.69
160_I 192_D 1.345 0.69
312_V 340_Q 1.341 0.68
322_V 372_L 1.337 0.68
163_F 193_C 1.327 0.67
160_I 193_C 1.325 0.67
236_W 305_Y 1.323 0.67
115_L 342_L 1.312 0.66
235_E 307_R 1.306 0.65
102_M 114_L 1.305 0.65
73_I 273_R 1.303 0.65
240_D 373_I 1.303 0.65
123_T 235_E 1.295 0.64
67_A 261_I 1.295 0.64
125_L 310_G 1.282 0.63
272_W 282_L 1.277 0.63
191_Q 195_Q 1.276 0.63
73_I 76_Q 1.274 0.62
255_E 263_S 1.27 0.62
67_A 73_I 1.264 0.62
120_D 235_E 1.258 0.61
351_L 374_T 1.257 0.61
105_A 340_Q 1.253 0.61
160_I 196_Q 1.252 0.61
102_M 117_Y 1.248 0.60
93_A 357_V 1.242 0.60
130_Y 156_Q 1.235 0.59
29_E 378_S 1.224 0.58
56_L 143_G 1.222 0.58
209_L 225_I 1.222 0.58
65_D 114_L 1.222 0.58
192_D 286_F 1.22 0.58
62_E 275_F 1.218 0.57
176_C 261_I 1.218 0.57
65_D 70_D 1.215 0.57
355_W 368_E 1.214 0.57
339_F 372_L 1.212 0.57
231_L 380_F 1.208 0.56
153_N 217_L 1.206 0.56
125_L 372_L 1.202 0.56
329_Y 376_D 1.201 0.56
173_Y 202_R 1.195 0.55
286_F 304_I 1.195 0.55
313_T 320_N 1.193 0.55
53_T 352_I 1.189 0.55
21_F 185_S 1.182 0.54
237_M 327_G 1.18 0.54
49_I 354_S 1.176 0.53
204_I 220_L 1.172 0.53
155_I 238_M 1.169 0.53
277_G 280_N 1.166 0.52
301_R 336_Y 1.162 0.52
174_F 190_L 1.161 0.52
175_C 228_A 1.158 0.52
299_Y 315_F 1.155 0.51
26_I 377_T 1.151 0.51
64_V 68_V 1.147 0.51
16_A 21_F 1.142 0.50
121_T 308_E 1.142 0.50
68_V 87_I 1.141 0.50
123_T 231_L 1.14 0.50
234_L 253_W 1.139 0.50
102_M 328_D 1.139 0.50
43_R 47_E 1.138 0.50
6_V 37_A 1.137 0.50
89_E 93_A 1.137 0.50
123_T 376_D 1.136 0.50
63_V 66_R 1.124 0.48
21_F 126_Y 1.124 0.48
199_Q 371_T 1.123 0.48
228_A 253_W 1.12 0.48
218_T 222_D 1.116 0.48
60_C 119_A 1.114 0.47
90_S 278_H 1.111 0.47
112_V 280_N 1.109 0.47
257_L 260_S 1.107 0.47
272_W 283_A 1.106 0.47
83_Y 238_M 1.105 0.47
135_W 303_P 1.104 0.46
313_T 323_D 1.104 0.46
38_Y 368_E 1.103 0.46
99_Y 229_F 1.102 0.46
106_W 385_I 1.101 0.46
9_R 40_F 1.1 0.46
352_I 366_I 1.099 0.46
53_T 361_A 1.082 0.44
44_Q 64_V 1.079 0.44
53_T 356_I 1.078 0.44
125_L 363_G 1.077 0.44
106_W 111_P 1.077 0.44
35_S 238_M 1.077 0.44
289_E 361_A 1.072 0.43
71_E 74_L 1.07 0.43
2_L 257_L 1.069 0.43
57_H 258_W 1.069 0.43
15_I 18_D 1.066 0.43
369_D 378_S 1.064 0.43
133_W 217_L 1.055 0.42
85_D 339_F 1.055 0.42
74_L 273_R 1.054 0.42
246_L 251_E 1.052 0.42
140_R 380_F 1.052 0.42
56_L 104_F 1.05 0.41
191_Q 242_N 1.05 0.41
205_Y 208_D 1.048 0.41
7_P 373_I 1.046 0.41
42_L 50_E 1.045 0.41
225_I 228_A 1.043 0.41
42_L 385_I 1.041 0.41
115_L 126_Y 1.04 0.40
31_Y 183_D 1.04 0.40
104_F 175_C 1.039 0.40
369_D 375_K 1.039 0.40
272_W 278_H 1.039 0.40
357_V 364_M 1.038 0.40
96_P 345_F 1.036 0.40
259_K 355_W 1.036 0.40
258_W 263_S 1.036 0.40
74_L 342_L 1.036 0.40
31_Y 374_T 1.032 0.40
165_E 358_D 1.032 0.40
132_Q 279_P 1.027 0.39
155_I 363_G 1.024 0.39
63_V 267_L 1.023 0.39
251_E 339_F 1.023 0.39
22_D 181_D 1.021 0.39
244_P 247_R 1.02 0.39
141_R 386_A 1.019 0.39
365_G 380_F 1.019 0.39
61_L 91_W 1.018 0.38
281_L 383_H 1.017 0.38
133_W 151_Q 1.014 0.38
166_L 254_V 1.014 0.38
176_C 205_Y 1.013 0.38
301_R 319_N 1.01 0.38
78_A 189_Y 1.009 0.38
40_F 183_D 1.004 0.37
15_I 381_V 1.002 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vobA20.97931000.272Contact Map0.533
2io8A20.96641000.292Contact Map0.542
3n6xA10.97421000.624Contact Map0.365
1gsaA10.534997.40.94Contact Map0.459
3vpbA40.516896.70.946Contact Map0.597
3vpdA20.527196.60.946Contact Map0.592
3r5xA40.534996.30.948Contact Map0.524
4iwxA10.586695.50.951Contact Map0.343
3se7A60.550494.40.954Contact Map0.394
4eg0A20.560794.30.955Contact Map0.601
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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