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OPENSEQ.org
YGIC - Uncharacterized protein YgiC
UniProt: P0ADT5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11165
Length: 386 (386)
Sequences: 432
Seq/Len: 1.12
YGIC
Paralog alert: 0.50 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: YGIC YJFC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_A 360_P 3.52 1.00
52_T 353_S 3.227 1.00
175_H 206_L 2.718 1.00
311_N 326_G 2.639 1.00
51_V 111_P 2.576 1.00
42_L 46_E 2.447 0.99
65_K 276_M 2.338 0.99
56_H 116_N 2.205 0.98
314_I 338_F 2.127 0.98
343_K 346_D 2.107 0.98
76_F 268_A 2.047 0.97
70_D 87_R 2.038 0.97
153_S 157_K 1.999 0.96
2_E 39_K 1.985 0.96
51_V 282_N 1.918 0.95
127_A 154_L 1.916 0.95
8_E 13_R 1.839 0.93
270_L 286_A 1.825 0.93
271_P 288_F 1.793 0.92
206_L 210_D 1.766 0.92
40_L 45_V 1.758 0.91
157_K 361_A 1.74 0.91
177_T 208_I 1.731 0.90
193_Q 205_F 1.725 0.90
329_G 332_G 1.686 0.89
180_R 209_D 1.681 0.89
99_S 116_N 1.651 0.87
300_V 314_I 1.638 0.87
193_Q 203_T 1.611 0.86
210_D 222_L 1.603 0.85
97_L 192_L 1.57 0.84
343_K 348_Y 1.543 0.82
272_L 276_M 1.54 0.82
27_Y 376_M 1.535 0.82
257_E 261_K 1.512 0.80
351_I 363_I 1.504 0.80
301_V 313_S 1.496 0.79
271_P 334_I 1.474 0.78
52_T 103_L 1.455 0.77
62_V 276_M 1.443 0.76
311_N 328_Y 1.441 0.76
66_V 72_L 1.425 0.75
64_E 113_L 1.42 0.74
104_A 339_H 1.417 0.74
178_C 205_F 1.383 0.71
165_L 174_L 1.382 0.71
66_V 263_I 1.365 0.70
193_Q 197_T 1.363 0.70
159_I 195_C 1.355 0.69
72_L 75_K 1.352 0.69
55_L 101_L 1.346 0.68
159_I 194_D 1.345 0.68
194_D 198_E 1.345 0.68
237_E 307_R 1.327 0.67
124_L 310_A 1.325 0.67
162_F 195_C 1.324 0.67
338_F 371_L 1.324 0.67
201_I 370_A 1.306 0.65
242_E 372_I 1.305 0.65
240_L 262_S 1.304 0.65
62_V 272_L 1.304 0.65
122_T 237_E 1.304 0.65
154_L 240_L 1.303 0.65
114_L 341_L 1.303 0.65
238_F 305_F 1.301 0.65
274_W 284_L 1.294 0.64
61_K 277_F 1.287 0.63
194_D 288_F 1.283 0.63
55_L 142_G 1.275 0.62
350_L 373_T 1.273 0.62
119_D 237_E 1.273 0.62
320_T 323_A 1.261 0.61
64_E 69_S 1.259 0.61
257_E 265_S 1.255 0.61
176_L 192_L 1.235 0.59
301_V 319_K 1.229 0.58
328_Y 375_D 1.227 0.58
239_M 326_G 1.225 0.58
159_I 198_E 1.222 0.57
354_W 367_E 1.216 0.57
29_E 377_S 1.212 0.57
50_E 312_V 1.211 0.56
233_L 379_F 1.207 0.56
288_F 304_I 1.204 0.56
124_L 371_L 1.203 0.56
178_C 263_I 1.201 0.55
21_F 187_G 1.198 0.55
6_I 37_Y 1.196 0.55
152_N 219_F 1.19 0.54
43_A 47_K 1.186 0.54
279_N 282_N 1.185 0.54
101_L 116_N 1.183 0.54
86_V 330_E 1.179 0.53
243_M 313_S 1.163 0.52
72_L 275_E 1.161 0.52
129_F 155_Q 1.161 0.52
120_T 308_E 1.161 0.52
312_V 339_H 1.156 0.51
122_T 375_D 1.154 0.51
16_A 21_F 1.154 0.51
52_T 351_I 1.15 0.51
227_I 230_L 1.149 0.51
105_W 384_F 1.144 0.50
122_T 233_L 1.143 0.50
21_F 125_Y 1.14 0.50
82_T 240_L 1.139 0.50
48_L 353_S 1.137 0.49
101_L 113_L 1.137 0.49
351_I 365_I 1.136 0.49
177_T 230_L 1.13 0.49
67_I 86_V 1.127 0.48
288_F 334_I 1.126 0.48
26_M 376_M 1.125 0.48
274_W 285_P 1.122 0.48
89_S 280_H 1.119 0.48
38_Y 367_E 1.114 0.47
175_H 204_E 1.112 0.47
301_V 335_V 1.112 0.47
95_P 344_F 1.107 0.47
70_D 73_M 1.104 0.46
98_Y 231_F 1.103 0.46
9_R 40_L 1.101 0.46
230_L 255_W 1.101 0.46
111_P 282_N 1.1 0.46
236_W 255_W 1.1 0.46
84_S 338_F 1.093 0.45
101_L 327_P 1.092 0.45
124_L 362_G 1.091 0.45
59_C 118_A 1.091 0.45
140_N 385_V 1.09 0.45
206_L 222_L 1.089 0.45
322_E 371_L 1.086 0.45
313_S 323_A 1.085 0.44
48_L 361_A 1.083 0.44
252_G 268_A 1.083 0.44
211_I 227_I 1.082 0.44
312_V 325_E 1.082 0.44
88_Q 92_T 1.081 0.44
132_W 219_F 1.08 0.44
42_L 49_E 1.074 0.43
56_H 260_W 1.072 0.43
368_D 377_S 1.071 0.43
139_L 147_G 1.07 0.43
55_L 103_L 1.069 0.43
299_Y 315_I 1.061 0.42
193_Q 244_F 1.061 0.42
74_T 83_W 1.06 0.42
2_E 259_A 1.059 0.42
220_T 224_D 1.059 0.42
62_V 65_K 1.059 0.42
149_D 384_F 1.058 0.42
62_V 269_L 1.054 0.42
84_S 165_L 1.052 0.41
44_Q 63_V 1.052 0.41
42_L 384_F 1.051 0.41
77_R 191_Y 1.05 0.41
31_Y 185_D 1.048 0.41
31_Y 373_T 1.048 0.41
283_L 382_H 1.046 0.41
313_S 320_T 1.045 0.41
52_T 360_P 1.044 0.41
178_C 277_F 1.043 0.40
101_L 216_K 1.042 0.40
134_W 303_P 1.041 0.40
253_V 338_F 1.041 0.40
368_D 374_Q 1.04 0.40
165_L 256_L 1.036 0.40
92_T 356_V 1.036 0.40
260_W 265_S 1.035 0.40
274_W 280_H 1.035 0.40
207_Y 210_D 1.033 0.40
40_L 185_D 1.032 0.39
132_W 150_Q 1.029 0.39
105_W 110_E 1.029 0.39
356_V 363_I 1.028 0.39
7_T 372_I 1.027 0.39
73_M 341_L 1.026 0.39
286_A 334_I 1.024 0.39
178_C 207_Y 1.023 0.39
242_E 383_I 1.022 0.39
105_W 111_P 1.021 0.38
261_K 354_W 1.016 0.38
60_L 90_W 1.011 0.38
52_T 355_L 1.009 0.37
22_N 183_V 1.006 0.37
15_K 18_E 1.005 0.37
63_V 67_I 1.001 0.37
364_G 379_F 1 0.37
4_V 7_T 1 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vobA20.97931000.277Contact Map0.552
2io8A20.96631000.296Contact Map0.554
3n6xA10.96891000.628Contact Map0.371
1gsaA10.525996.80.945Contact Map0.444
3vpbA40.51395.50.952Contact Map0.56
3vpdA20.520795.40.952Contact Map0.546
3r5xA40.528594.70.954Contact Map0.503
3se7A60.549292.60.958Contact Map0.37
4eg0A20.554492.50.958Contact Map0.554
4iwxA10.580391.80.959Contact Map0.288
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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