| UniProt: | P32695 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11932 | ||
| Length: | 330 (310) | ||
| Sequences: | 2884 | ||
| Seq/Len: | 9.30 |
| DUSA
Paralog alert: 0.55 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: DUSA DUSB DUSC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 200_K | 228_D | 4.962 | 1.00 | |
| 32_L | 269_P | 4.27 | 1.00 | |
| 86_E | 132_S | 3.4 | 1.00 | |
| 216_S | 219_E | 3.187 | 1.00 | |
| 215_K | 219_E | 3.103 | 1.00 | |
| 78_L | 95_L | 2.881 | 1.00 | |
| 128_R | 166_E | 2.871 | 1.00 | |
| 222_A | 226_H | 2.791 | 1.00 | |
| 64_H | 91_D | 2.68 | 1.00 | |
| 124_V | 165_C | 2.618 | 1.00 | |
| 221_K | 225_Q | 2.538 | 1.00 | |
| 125_K | 129_D | 2.526 | 1.00 | |
| 194_P | 226_H | 2.432 | 1.00 | |
| 26_C | 30_L | 2.296 | 1.00 | |
| 82_A | 131_V | 2.272 | 1.00 | |
| 115_G | 143_I | 2.226 | 1.00 | |
| 198_Q | 201_R | 2.195 | 1.00 | |
| 210_I | 223_H | 2.19 | 1.00 | |
| 221_K | 249_E | 2.182 | 1.00 | |
| 160_S | 206_L | 2.158 | 1.00 | |
| 197_Y | 201_R | 2.15 | 1.00 | |
| 248_R | 255_D | 2.051 | 1.00 | |
| 160_S | 205_H | 2.05 | 1.00 | |
| 215_K | 235_E | 2.044 | 1.00 | |
| 141_I | 195_R | 1.96 | 1.00 | |
| 219_E | 222_A | 1.949 | 1.00 | |
| 214_I | 223_H | 1.932 | 1.00 | |
| 80_Q | 83_K | 1.93 | 1.00 | |
| 218_E | 222_A | 1.919 | 1.00 | |
| 97_V | 120_V | 1.887 | 1.00 | |
| 270_Y | 291_L | 1.843 | 1.00 | |
| 192_D | 195_R | 1.812 | 1.00 | |
| 76_A | 80_Q | 1.805 | 1.00 | |
| 78_L | 127_M | 1.8 | 1.00 | |
| 121_A | 162_K | 1.799 | 1.00 | |
| 72_G | 78_L | 1.783 | 1.00 | |
| 38_L | 67_A | 1.759 | 1.00 | |
| 120_V | 155_F | 1.747 | 1.00 | |
| 222_A | 225_Q | 1.734 | 1.00 | |
| 86_E | 131_V | 1.725 | 1.00 | |
| 122_D | 125_K | 1.722 | 1.00 | |
| 108_M | 116_N | 1.714 | 1.00 | |
| 116_N | 119_L | 1.689 | 1.00 | |
| 196_V | 210_I | 1.682 | 1.00 | |
| 67_A | 92_E | 1.671 | 1.00 | |
| 131_V | 135_V | 1.644 | 1.00 | |
| 303_R | 307_E | 1.643 | 1.00 | |
| 95_L | 127_M | 1.643 | 1.00 | |
| 267_M | 288_M | 1.639 | 1.00 | |
| 259_D | 262_A | 1.634 | 1.00 | |
| 167_M | 209_S | 1.613 | 1.00 | |
| 197_Y | 226_H | 1.611 | 1.00 | |
| 74_D | 77_A | 1.61 | 1.00 | |
| 121_A | 125_K | 1.609 | 1.00 | |
| 203_F | 208_M | 1.609 | 1.00 | |
| 118_Q | 122_D | 1.587 | 1.00 | |
| 139_T | 170_I | 1.58 | 1.00 | |
| 152_L | 199_L | 1.579 | 1.00 | |
| 210_I | 214_I | 1.557 | 1.00 | |
| 154_D | 157_N | 1.557 | 1.00 | |
| 170_I | 199_L | 1.553 | 1.00 | |
| 118_Q | 158_T | 1.548 | 1.00 | |
| 274_E | 279_T | 1.533 | 1.00 | |
| 68_L | 85_A | 1.526 | 1.00 | |
| 119_L | 122_D | 1.52 | 1.00 | |
| 37_T | 247_D | 1.516 | 1.00 | |
| 197_Y | 223_H | 1.503 | 1.00 | |
| 124_V | 162_K | 1.499 | 1.00 | |
| 210_I | 227_M | 1.45 | 1.00 | |
| 11_G | 37_T | 1.446 | 1.00 | |
| 195_R | 198_Q | 1.442 | 1.00 | |
| 121_A | 158_T | 1.435 | 0.99 | |
| 75_P | 79_A | 1.418 | 0.99 | |
| 14_S | 209_S | 1.412 | 0.99 | |
| 114_M | 155_F | 1.4 | 0.99 | |
| 38_L | 92_E | 1.393 | 0.99 | |
| 200_K | 208_M | 1.373 | 0.99 | |
| 86_E | 133_I | 1.368 | 0.99 | |
| 13_F | 246_V | 1.367 | 0.99 | |
| 145_D | 178_S | 1.366 | 0.99 | |
| 111_A | 175_A | 1.364 | 0.99 | |
| 209_S | 231_M | 1.356 | 0.99 | |
| 232_V | 246_V | 1.355 | 0.99 | |
| 47_G | 77_A | 1.339 | 0.99 | |
| 137_V | 165_C | 1.323 | 0.99 | |
| 144_D | 147_D | 1.323 | 0.99 | |
| 209_S | 229_G | 1.322 | 0.99 | |
| 218_E | 254_S | 1.32 | 0.99 | |
| 172_A | 196_V | 1.316 | 0.99 | |
| 114_M | 139_T | 1.316 | 0.99 | |
| 31_R | 65_P | 1.312 | 0.99 | |
| 220_A | 230_V | 1.311 | 0.99 | |
| 85_A | 93_I | 1.293 | 0.99 | |
| 125_K | 162_K | 1.292 | 0.99 | |
| 13_F | 230_V | 1.28 | 0.99 | |
| 160_S | 203_F | 1.277 | 0.99 | |
| 75_P | 119_L | 1.273 | 0.99 | |
| 248_R | 253_S | 1.273 | 0.99 | |
| 157_N | 160_S | 1.262 | 0.98 | |
| 128_R | 135_V | 1.23 | 0.98 | |
| 79_A | 130_V | 1.23 | 0.98 | |
| 239_N | 245_A | 1.228 | 0.98 | |
| 274_E | 277_Q | 1.225 | 0.98 | |
| 83_K | 130_V | 1.221 | 0.98 | |
| 153_C | 202_D | 1.218 | 0.98 | |
| 157_N | 202_D | 1.216 | 0.98 | |
| 40_Y | 67_A | 1.215 | 0.98 | |
| 273_R | 276_S | 1.206 | 0.98 | |
| 244_A | 262_A | 1.198 | 0.98 | |
| 203_F | 206_L | 1.186 | 0.97 | |
| 261_V | 265_R | 1.185 | 0.97 | |
| 267_M | 284_I | 1.183 | 0.97 | |
| 121_A | 161_G | 1.179 | 0.97 | |
| 157_N | 161_G | 1.177 | 0.97 | |
| 137_V | 159_V | 1.169 | 0.97 | |
| 269_P | 273_R | 1.167 | 0.97 | |
| 149_Y | 202_D | 1.153 | 0.97 | |
| 153_C | 198_Q | 1.146 | 0.97 | |
| 24_R | 58_A | 1.141 | 0.96 | |
| 83_K | 87_A | 1.14 | 0.96 | |
| 156_I | 199_L | 1.135 | 0.96 | |
| 152_L | 195_R | 1.132 | 0.96 | |
| 193_Y | 223_H | 1.131 | 0.96 | |
| 268_Y | 272_E | 1.128 | 0.96 | |
| 141_I | 192_D | 1.127 | 0.96 | |
| 136_T | 167_M | 1.126 | 0.96 | |
| 124_V | 159_V | 1.123 | 0.96 | |
| 286_R | 290_G | 1.113 | 0.96 | |
| 191_L | 213_G | 1.105 | 0.96 | |
| 14_S | 38_L | 1.105 | 0.96 | |
| 272_E | 276_S | 1.105 | 0.96 | |
| 155_F | 159_V | 1.104 | 0.96 | |
| 304_Y | 308_N | 1.099 | 0.95 | |
| 217_L | 249_E | 1.095 | 0.95 | |
| 78_L | 123_C | 1.079 | 0.95 | |
| 98_G | 211_N | 1.076 | 0.95 | |
| 198_Q | 202_D | 1.066 | 0.94 | |
| 117_A | 154_D | 1.06 | 0.94 | |
| 157_N | 203_F | 1.054 | 0.94 | |
| 139_T | 155_F | 1.053 | 0.94 | |
| 178_S | 182_P | 1.05 | 0.94 | |
| 300_Q | 303_R | 1.046 | 0.94 | |
| 218_E | 249_E | 1.034 | 0.93 | |
| 16_A | 233_G | 1.031 | 0.93 | |
| 158_T | 162_K | 1.02 | 0.92 | |
| 156_I | 168_F | 1.019 | 0.92 | |
| 114_M | 120_V | 1.019 | 0.92 | |
| 223_H | 227_M | 1.013 | 0.92 | |
| 28_Y | 273_R | 1.012 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3b0pA | 2 | 0.9667 | 100 | 0.34 | Contact Map | 0.777 |
| 1vhnA | 1 | 0.9212 | 100 | 0.388 | Contact Map | 0.762 |
| 3w9zA | 1 | 0.9152 | 100 | 0.401 | Contact Map | 0.731 |
| 4bfaA | 2 | 0.9333 | 100 | 0.407 | Contact Map | 0.742 |
| 1gteA | 4 | 0.9576 | 100 | 0.638 | Contact Map | 0.709 |
| 3l5aA | 1 | 0.8727 | 100 | 0.644 | Contact Map | 0.662 |
| 3sgzA | 3 | 0.7758 | 100 | 0.661 | Contact Map | 0.564 |
| 4jicA | 3 | 0.8273 | 100 | 0.661 | Contact Map | 0.653 |
| 4b5nA | 1 | 0.7606 | 100 | 0.661 | Contact Map | 0.589 |
| 3tjlA | 1 | 0.8636 | 100 | 0.661 | Contact Map | 0.536 |
Sequence Conservation (Image Generated using WebLogo v3)