| UniProt: | P31826 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11742 | ||
| Length: | 561 (532) | ||
| Sequences: | 8514 | ||
| Seq/Len: | 16.00 |
| YDDA
Paralog alert: 0.79 [within 20: 0.28] - ratio of genomes with paralogs Cluster includes: CYDC CYDD MDLA MDLB MSBA YDDA YOJI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 371_D | 385_N | 6.84 | 1.00 | |
| 391_S | 394_K | 5.593 | 1.00 | |
| 370_A | 423_D | 5.283 | 1.00 | |
| 368_Q | 389_H | 5.258 | 1.00 | |
| 394_K | 553_D | 4.802 | 1.00 | |
| 370_A | 425_S | 4.718 | 1.00 | |
| 445_K | 458_D | 4.519 | 1.00 | |
| 442_G | 446_E | 4.508 | 1.00 | |
| 471_G | 481_D | 4.423 | 1.00 | |
| 466_H | 471_G | 4.397 | 1.00 | |
| 471_G | 475_A | 4.182 | 1.00 | |
| 369_V | 372_A | 3.806 | 1.00 | |
| 457_D | 460_S | 3.613 | 1.00 | |
| 431_W | 505_P | 3.399 | 1.00 | |
| 410_L | 541_V | 3.393 | 1.00 | |
| 410_L | 509_F | 3.304 | 1.00 | |
| 448_I | 465_L | 3.286 | 1.00 | |
| 445_K | 449_C | 3.206 | 1.00 | |
| 366_A | 389_H | 3.195 | 1.00 | |
| 462_S | 466_H | 3.174 | 1.00 | |
| 373_S | 385_N | 3.161 | 1.00 | |
| 368_Q | 425_S | 3.042 | 1.00 | |
| 463_E | 467_Q | 3.002 | 1.00 | |
| 448_I | 461_L | 2.972 | 1.00 | |
| 458_D | 462_S | 2.959 | 1.00 | |
| 465_L | 481_D | 2.952 | 1.00 | |
| 445_K | 461_L | 2.849 | 1.00 | |
| 415_H | 418_P | 2.821 | 1.00 | |
| 366_A | 392_P | 2.811 | 1.00 | |
| 470_L | 473_L | 2.729 | 1.00 | |
| 381_I | 384_E | 2.727 | 1.00 | |
| 390_V | 396_L | 2.725 | 1.00 | |
| 388_F | 555_C | 2.694 | 1.00 | |
| 366_A | 391_S | 2.634 | 1.00 | |
| 445_K | 482_R | 2.599 | 1.00 | |
| 373_S | 421_K | 2.544 | 1.00 | |
| 369_V | 388_F | 2.544 | 1.00 | |
| 390_V | 539_I | 2.496 | 1.00 | |
| 462_S | 471_G | 2.468 | 1.00 | |
| 383_L | 386_L | 2.359 | 1.00 | |
| 465_L | 474_A | 2.335 | 1.00 | |
| 449_C | 461_L | 2.319 | 1.00 | |
| 367_V | 539_I | 2.311 | 1.00 | |
| 463_E | 466_H | 2.273 | 1.00 | |
| 373_S | 381_I | 2.268 | 1.00 | |
| 462_S | 475_A | 2.229 | 1.00 | |
| 170_V | 174_E | 2.187 | 1.00 | |
| 76_L | 80_A | 2.185 | 1.00 | |
| 375_R | 381_I | 2.175 | 1.00 | |
| 459_K | 462_S | 2.135 | 1.00 | |
| 504_R | 536_S | 2.111 | 1.00 | |
| 375_R | 420_F | 2.073 | 1.00 | |
| 449_C | 458_D | 2.053 | 1.00 | |
| 453_P | 460_S | 2.04 | 1.00 | |
| 371_D | 387_N | 2.024 | 1.00 | |
| 464_V | 468_V | 2.013 | 1.00 | |
| 402_S | 521_E | 1.995 | 1.00 | |
| 398_L | 409_L | 1.99 | 1.00 | |
| 346_Y | 350_Q | 1.973 | 1.00 | |
| 522_A | 544_Q | 1.958 | 1.00 | |
| 388_F | 409_L | 1.955 | 1.00 | |
| 542_T | 547_V | 1.953 | 1.00 | |
| 452_L | 460_S | 1.945 | 1.00 | |
| 374_I | 408_T | 1.922 | 1.00 | |
| 517_L | 525_L | 1.915 | 1.00 | |
| 467_Q | 501_I | 1.904 | 1.00 | |
| 456_V | 502_L | 1.897 | 1.00 | |
| 176_A | 300_Q | 1.886 | 1.00 | |
| 465_L | 471_G | 1.869 | 1.00 | |
| 173_W | 177_G | 1.851 | 1.00 | |
| 460_S | 463_E | 1.849 | 1.00 | |
| 395_W | 540_M | 1.839 | 1.00 | |
| 395_W | 551_A | 1.833 | 1.00 | |
| 396_L | 553_D | 1.827 | 1.00 | |
| 469_G | 524_R | 1.804 | 1.00 | |
| 444_L | 495_I | 1.802 | 1.00 | |
| 72_W | 76_L | 1.785 | 1.00 | |
| 104_R | 108_T | 1.766 | 1.00 | |
| 61_N | 309_G | 1.754 | 1.00 | |
| 61_N | 307_N | 1.74 | 1.00 | |
| 257_L | 261_F | 1.739 | 1.00 | |
| 500_L | 508_I | 1.724 | 1.00 | |
| 531_E | 534_P | 1.681 | 1.00 | |
| 460_S | 504_R | 1.671 | 1.00 | |
| 472_K | 475_A | 1.668 | 1.00 | |
| 412_T | 424_I | 1.659 | 1.00 | |
| 527_R | 531_E | 1.659 | 1.00 | |
| 448_I | 502_L | 1.65 | 1.00 | |
| 253_Q | 450_K | 1.614 | 1.00 | |
| 542_T | 548_W | 1.601 | 1.00 | |
| 456_V | 460_S | 1.598 | 1.00 | |
| 419_W | 424_I | 1.593 | 1.00 | |
| 426_S | 507_W | 1.582 | 1.00 | |
| 207_L | 211_K | 1.576 | 1.00 | |
| 465_L | 470_L | 1.574 | 1.00 | |
| 173_W | 195_V | 1.563 | 1.00 | |
| 414_S | 432_Y | 1.562 | 1.00 | |
| 368_Q | 423_D | 1.559 | 1.00 | |
| 369_V | 413_L | 1.556 | 1.00 | |
| 523_I | 527_R | 1.543 | 1.00 | |
| 215_R | 218_P | 1.537 | 1.00 | |
| 226_S | 263_T | 1.531 | 1.00 | |
| 452_L | 455_P | 1.53 | 1.00 | |
| 476_R | 491_E | 1.523 | 1.00 | |
| 530_R | 550_L | 1.522 | 1.00 | |
| 300_Q | 305_Q | 1.511 | 1.00 | |
| 467_Q | 531_E | 1.509 | 1.00 | |
| 249_A | 252_L | 1.491 | 1.00 | |
| 57_N | 61_N | 1.478 | 1.00 | |
| 396_L | 539_I | 1.467 | 1.00 | |
| 299_P | 303_S | 1.466 | 1.00 | |
| 533_L | 538_V | 1.43 | 1.00 | |
| 108_T | 112_L | 1.41 | 1.00 | |
| 402_S | 494_R | 1.41 | 1.00 | |
| 462_S | 481_D | 1.408 | 1.00 | |
| 367_V | 426_S | 1.407 | 0.99 | |
| 221_V | 343_D | 1.397 | 0.99 | |
| 469_G | 521_E | 1.395 | 0.99 | |
| 464_V | 501_I | 1.393 | 0.99 | |
| 448_I | 495_I | 1.389 | 0.99 | |
| 14_K | 350_Q | 1.381 | 0.99 | |
| 474_A | 481_D | 1.379 | 0.99 | |
| 458_D | 461_L | 1.374 | 0.99 | |
| 177_G | 193_Y | 1.365 | 0.99 | |
| 398_L | 555_C | 1.351 | 0.99 | |
| 143_D | 344_R | 1.348 | 0.99 | |
| 462_S | 465_L | 1.341 | 0.99 | |
| 399_K | 545_P | 1.339 | 0.99 | |
| 229_T | 263_T | 1.339 | 0.99 | |
| 446_E | 449_C | 1.332 | 0.99 | |
| 473_L | 491_E | 1.325 | 0.99 | |
| 374_I | 412_T | 1.323 | 0.99 | |
| 460_S | 502_L | 1.319 | 0.99 | |
| 449_C | 456_V | 1.313 | 0.99 | |
| 174_E | 177_G | 1.309 | 0.99 | |
| 374_I | 417_W | 1.309 | 0.99 | |
| 470_L | 474_A | 1.306 | 0.99 | |
| 139_R | 347_E | 1.304 | 0.99 | |
| 472_K | 476_R | 1.292 | 0.99 | |
| 370_A | 387_N | 1.288 | 0.99 | |
| 172_L | 176_A | 1.286 | 0.99 | |
| 73_Q | 77_W | 1.282 | 0.99 | |
| 255_Q | 259_D | 1.276 | 0.99 | |
| 443_L | 446_E | 1.266 | 0.99 | |
| 324_N | 328_F | 1.266 | 0.99 | |
| 226_S | 267_N | 1.265 | 0.99 | |
| 146_L | 341_V | 1.255 | 0.99 | |
| 489_S | 494_R | 1.249 | 0.99 | |
| 110_Y | 114_R | 1.247 | 0.99 | |
| 413_L | 539_I | 1.244 | 0.98 | |
| 464_V | 502_L | 1.234 | 0.98 | |
| 396_L | 555_C | 1.234 | 0.98 | |
| 105_E | 109_D | 1.231 | 0.98 | |
| 431_W | 500_L | 1.224 | 0.98 | |
| 395_W | 538_V | 1.221 | 0.98 | |
| 122_Y | 126_I | 1.214 | 0.98 | |
| 240_Q | 243_L | 1.206 | 0.98 | |
| 437_P | 496_A | 1.206 | 0.98 | |
| 368_Q | 387_N | 1.204 | 0.98 | |
| 470_L | 476_R | 1.203 | 0.98 | |
| 226_S | 229_T | 1.202 | 0.98 | |
| 394_K | 552_D | 1.198 | 0.98 | |
| 397_L | 551_A | 1.19 | 0.98 | |
| 46_V | 49_Q | 1.187 | 0.98 | |
| 118_D | 122_Y | 1.186 | 0.98 | |
| 512_E | 543_H | 1.178 | 0.98 | |
| 104_R | 112_L | 1.177 | 0.98 | |
| 463_E | 504_R | 1.176 | 0.98 | |
| 301_F | 306_I | 1.171 | 0.98 | |
| 295_F | 299_P | 1.167 | 0.97 | |
| 211_K | 215_R | 1.164 | 0.97 | |
| 373_S | 384_E | 1.162 | 0.97 | |
| 385_N | 421_K | 1.16 | 0.97 | |
| 469_G | 527_R | 1.159 | 0.97 | |
| 468_V | 498_A | 1.158 | 0.97 | |
| 222_E | 226_S | 1.136 | 0.97 | |
| 514_T | 522_A | 1.134 | 0.97 | |
| 468_V | 494_R | 1.128 | 0.97 | |
| 215_R | 219_L | 1.128 | 0.97 | |
| 390_V | 537_G | 1.125 | 0.97 | |
| 391_S | 553_D | 1.123 | 0.97 | |
| 224_Q | 227_E | 1.121 | 0.97 | |
| 549_N | 554_I | 1.119 | 0.96 | |
| 176_A | 193_Y | 1.117 | 0.96 | |
| 367_V | 390_V | 1.112 | 0.96 | |
| 83_G | 87_L | 1.111 | 0.96 | |
| 342_I | 346_Y | 1.11 | 0.96 | |
| 433_V | 497_L | 1.109 | 0.96 | |
| 147_L | 345_L | 1.103 | 0.96 | |
| 505_P | 536_S | 1.098 | 0.96 | |
| 392_P | 506_K | 1.093 | 0.96 | |
| 67_E | 70_K | 1.088 | 0.96 | |
| 494_R | 517_L | 1.088 | 0.96 | |
| 526_L | 542_T | 1.083 | 0.96 | |
| 475_A | 480_H | 1.081 | 0.95 | |
| 372_A | 412_T | 1.079 | 0.95 | |
| 177_G | 196_Y | 1.078 | 0.95 | |
| 172_L | 314_S | 1.076 | 0.95 | |
| 466_H | 475_A | 1.069 | 0.95 | |
| 136_P | 348_F | 1.068 | 0.95 | |
| 98_L | 102_R | 1.068 | 0.95 | |
| 381_I | 421_K | 1.064 | 0.95 | |
| 106_W | 110_Y | 1.055 | 0.95 | |
| 222_E | 225_R | 1.053 | 0.95 | |
| 69_D | 73_Q | 1.052 | 0.95 | |
| 236_Q | 243_L | 1.05 | 0.94 | |
| 262_H | 266_E | 1.042 | 0.94 | |
| 544_Q | 547_V | 1.037 | 0.94 | |
| 109_D | 113_N | 1.036 | 0.94 | |
| 119_K | 122_Y | 1.035 | 0.94 | |
| 497_L | 510_L | 1.03 | 0.94 | |
| 242_E | 411_K | 1.028 | 0.94 | |
| 139_R | 344_R | 1.024 | 0.93 | |
| 245_A | 250_E | 1.022 | 0.93 | |
| 445_K | 462_S | 1.022 | 0.93 | |
| 468_V | 497_L | 1.022 | 0.93 | |
| 365_H | 392_P | 1.019 | 0.93 | |
| 419_W | 423_D | 1.015 | 0.93 | |
| 397_L | 548_W | 1.013 | 0.93 | |
| 367_V | 507_W | 1.008 | 0.93 | |
| 373_S | 420_F | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3qf4B | 1 | 0.9465 | 100 | 0.21 | Contact Map | 0.682 |
| 4a82A | 4 | 0.9287 | 100 | 0.218 | Contact Map | 0.079 |
| 3b60A | 4 | 0.9483 | 100 | 0.218 | Contact Map | 0.711 |
| 4f4cA | 1 | 0.9465 | 100 | 0.218 | Contact Map | 0.7 |
| 3b5xA | 2 | 0.9483 | 100 | 0.218 | Contact Map | 0.115 |
| 2yl4A | 1 | 0.9376 | 100 | 0.221 | Contact Map | 0.712 |
| 3qf4A | 1 | 0.943 | 100 | 0.225 | Contact Map | 0.734 |
| 3g5uA | 2 | 0.9483 | 100 | 0.234 | Contact Map | 0.659 |
| 3nh6A | 1 | 0.4332 | 100 | 0.473 | Contact Map | 0.793 |
| 3vx4A | 2 | 0.3993 | 100 | 0.527 | Contact Map | 0.847 |
Sequence Conservation (Image Generated using WebLogo v3)