| UniProt: | P31470 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11728 | ||
| Length: | 240 (236) | ||
| Sequences: | 2375 | ||
| Seq/Len: | 10.06 |
| YIEK
Paralog alert: 0.34 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: AGAI NAGB YIEK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 81_T | 85_N | 3.238 | 1.00 | |
| 196_A | 232_A | 2.758 | 1.00 | |
| 105_N | 108_E | 2.731 | 1.00 | |
| 7_E | 231_K | 2.691 | 1.00 | |
| 200_Q | 236_E | 2.645 | 1.00 | |
| 46_Y | 49_T | 2.563 | 1.00 | |
| 101_L | 176_V | 2.503 | 1.00 | |
| 111_Q | 115_R | 2.47 | 1.00 | |
| 84_R | 89_T | 2.464 | 1.00 | |
| 128_A | 197_G | 2.285 | 1.00 | |
| 188_N | 224_S | 2.22 | 1.00 | |
| 229_A | 234_A | 2.195 | 1.00 | |
| 85_N | 89_T | 2.18 | 1.00 | |
| 202_L | 229_A | 2.089 | 1.00 | |
| 99_Q | 112_K | 2.01 | 1.00 | |
| 56_W | 92_G | 2.009 | 1.00 | |
| 20_L | 43_M | 1.986 | 1.00 | |
| 73_K | 80_I | 1.967 | 1.00 | |
| 8_D | 11_E | 1.905 | 1.00 | |
| 120_D | 187_K | 1.854 | 1.00 | |
| 200_Q | 204_N | 1.833 | 1.00 | |
| 39_T | 192_I | 1.796 | 1.00 | |
| 12_M | 194_S | 1.794 | 1.00 | |
| 23_Y | 188_N | 1.793 | 1.00 | |
| 107_R | 111_Q | 1.746 | 1.00 | |
| 61_Y | 99_Q | 1.723 | 1.00 | |
| 14_R | 46_Y | 1.71 | 1.00 | |
| 62_F | 88_F | 1.707 | 1.00 | |
| 21_L | 50_L | 1.698 | 1.00 | |
| 9_Y | 13_S | 1.69 | 1.00 | |
| 13_S | 42_G | 1.679 | 1.00 | |
| 35_T | 65_F | 1.657 | 1.00 | |
| 68_I | 71_R | 1.636 | 1.00 | |
| 80_I | 84_R | 1.628 | 1.00 | |
| 126_L | 193_V | 1.619 | 1.00 | |
| 122_V | 186_A | 1.619 | 1.00 | |
| 104_D | 108_E | 1.609 | 1.00 | |
| 196_A | 235_A | 1.609 | 1.00 | |
| 184_M | 218_V | 1.604 | 1.00 | |
| 6_T | 15_V | 1.602 | 1.00 | |
| 153_G | 159_V | 1.589 | 1.00 | |
| 203_K | 207_Q | 1.578 | 1.00 | |
| 20_L | 32_L | 1.574 | 1.00 | |
| 80_I | 100_K | 1.571 | 1.00 | |
| 23_Y | 30_V | 1.565 | 1.00 | |
| 61_Y | 97_N | 1.561 | 1.00 | |
| 19_H | 228_I | 1.536 | 1.00 | |
| 18_H | 50_L | 1.522 | 1.00 | |
| 58_D | 92_G | 1.518 | 1.00 | |
| 16_A | 43_M | 1.516 | 1.00 | |
| 193_V | 202_L | 1.501 | 1.00 | |
| 64_N | 83_L | 1.471 | 1.00 | |
| 76_E | 81_T | 1.447 | 1.00 | |
| 167_D | 170_L | 1.442 | 1.00 | |
| 43_M | 123_V | 1.437 | 1.00 | |
| 130_G | 214_V | 1.435 | 1.00 | |
| 41_K | 86_L | 1.426 | 1.00 | |
| 133_C | 183_I | 1.394 | 0.99 | |
| 108_E | 112_K | 1.377 | 0.99 | |
| 63_Y | 116_E | 1.37 | 0.99 | |
| 145_Q | 185_A | 1.345 | 0.99 | |
| 189_L | 225_L | 1.336 | 0.99 | |
| 113_L | 119_L | 1.328 | 0.99 | |
| 166_G | 170_L | 1.324 | 0.99 | |
| 150_P | 174_S | 1.322 | 0.99 | |
| 93_I | 97_N | 1.321 | 0.99 | |
| 21_L | 55_P | 1.314 | 0.99 | |
| 199_A | 235_A | 1.301 | 0.99 | |
| 126_L | 205_V | 1.286 | 0.99 | |
| 6_T | 12_M | 1.282 | 0.99 | |
| 88_F | 98_I | 1.274 | 0.99 | |
| 178_M | 182_S | 1.253 | 0.99 | |
| 128_A | 160_A | 1.249 | 0.99 | |
| 33_A | 122_V | 1.245 | 0.98 | |
| 19_H | 188_N | 1.244 | 0.98 | |
| 9_Y | 42_G | 1.241 | 0.98 | |
| 18_H | 22_G | 1.239 | 0.98 | |
| 29_R | 61_Y | 1.238 | 0.98 | |
| 16_A | 190_L | 1.233 | 0.98 | |
| 205_V | 227_V | 1.213 | 0.98 | |
| 230_D | 233_A | 1.199 | 0.98 | |
| 45_E | 86_L | 1.194 | 0.98 | |
| 51_V | 54_K | 1.191 | 0.98 | |
| 43_M | 192_I | 1.19 | 0.98 | |
| 84_R | 95_E | 1.186 | 0.98 | |
| 28_R | 59_N | 1.185 | 0.98 | |
| 12_M | 228_I | 1.181 | 0.98 | |
| 204_N | 214_V | 1.172 | 0.98 | |
| 33_A | 65_F | 1.169 | 0.97 | |
| 202_L | 227_V | 1.165 | 0.97 | |
| 78_V | 81_T | 1.162 | 0.97 | |
| 41_K | 45_E | 1.162 | 0.97 | |
| 6_T | 228_I | 1.151 | 0.97 | |
| 74_E | 81_T | 1.139 | 0.97 | |
| 108_E | 111_Q | 1.139 | 0.97 | |
| 9_Y | 194_S | 1.128 | 0.97 | |
| 202_L | 205_V | 1.124 | 0.97 | |
| 234_A | 237_L | 1.123 | 0.97 | |
| 22_G | 26_K | 1.12 | 0.96 | |
| 5_I | 234_A | 1.118 | 0.96 | |
| 16_A | 192_I | 1.116 | 0.96 | |
| 56_W | 59_N | 1.107 | 0.96 | |
| 61_Y | 94_K | 1.105 | 0.96 | |
| 94_K | 97_N | 1.103 | 0.96 | |
| 24_M | 60_C | 1.102 | 0.96 | |
| 139_T | 147_V | 1.102 | 0.96 | |
| 19_H | 190_L | 1.099 | 0.96 | |
| 154_E | 160_A | 1.097 | 0.96 | |
| 16_A | 228_I | 1.093 | 0.96 | |
| 30_V | 60_C | 1.091 | 0.96 | |
| 20_L | 121_L | 1.081 | 0.95 | |
| 110_D | 182_S | 1.067 | 0.95 | |
| 48_T | 90_P | 1.064 | 0.95 | |
| 4_I | 228_I | 1.06 | 0.95 | |
| 24_M | 30_V | 1.06 | 0.95 | |
| 31_N | 63_Y | 1.049 | 0.94 | |
| 31_N | 61_Y | 1.039 | 0.94 | |
| 40_P | 44_Y | 1.039 | 0.94 | |
| 39_T | 194_S | 1.034 | 0.94 | |
| 46_Y | 50_L | 1.032 | 0.94 | |
| 95_E | 98_I | 1.028 | 0.94 | |
| 114_A | 185_A | 1.026 | 0.94 | |
| 188_N | 226_M | 1.001 | 0.92 | |
| 111_Q | 114_A | 1.001 | 0.92 | |
| 207_Q | 237_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3icoA | 4 | 0.9292 | 100 | 0.091 | Contact Map | 0.79 |
| 3tx2A | 1 | 0.925 | 100 | 0.094 | Contact Map | 0.745 |
| 3oc6A | 1 | 0.9208 | 100 | 0.095 | Contact Map | 0.755 |
| 3eb9A | 2 | 0.9333 | 100 | 0.108 | Contact Map | 0.761 |
| 1vl1A | 1 | 0.8667 | 100 | 0.147 | Contact Map | 0.729 |
| 3lwdA | 1 | 0.8833 | 100 | 0.15 | Contact Map | 0.577 |
| 3e15A | 4 | 0.9792 | 100 | 0.152 | Contact Map | 0.65 |
| 3cssA | 1 | 0.9292 | 100 | 0.165 | Contact Map | 0.677 |
| 3lhiA | 1 | 0.8958 | 100 | 0.185 | Contact Map | 0.573 |
| 1ne7A | 6 | 0.9875 | 100 | 0.186 | Contact Map | 0.877 |
Sequence Conservation (Image Generated using WebLogo v3)