| UniProt: | P28861 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11518 | ||
| Length: | 248 (233) | ||
| Sequences: | 7964 | ||
| Seq/Len: | 34.18 |
| FENR
Paralog alert: 0.76 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: FENR FRE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 108_T | 136_N | 3.45 | 1.00 | |
| 83_K | 86_D | 3.313 | 1.00 | |
| 8_K | 87_E | 2.932 | 1.00 | |
| 8_K | 25_H | 2.929 | 1.00 | |
| 6_T | 87_E | 2.792 | 1.00 | |
| 23_T | 62_D | 2.662 | 1.00 | |
| 11_K | 23_T | 2.637 | 1.00 | |
| 10_T | 25_H | 2.631 | 1.00 | |
| 21_S | 64_E | 2.558 | 1.00 | |
| 15_W | 21_S | 2.55 | 1.00 | |
| 126_Q | 154_L | 2.519 | 1.00 | |
| 152_L | 156_Q | 2.517 | 1.00 | |
| 9_V | 82_L | 2.492 | 1.00 | |
| 40_G | 89_Q | 2.383 | 1.00 | |
| 11_K | 84_P | 2.362 | 1.00 | |
| 14_N | 20_F | 2.355 | 1.00 | |
| 127_L | 131_L | 2.325 | 1.00 | |
| 12_V | 20_F | 2.3 | 1.00 | |
| 13_Q | 21_S | 2.25 | 1.00 | |
| 6_T | 89_Q | 2.246 | 1.00 | |
| 23_T | 64_E | 2.219 | 1.00 | |
| 7_G | 90_V | 2.21 | 1.00 | |
| 113_A | 121_Y | 2.207 | 1.00 | |
| 114_T | 214_N | 2.131 | 1.00 | |
| 143_A | 149_L | 2.124 | 1.00 | |
| 7_G | 24_V | 2.073 | 1.00 | |
| 37_T | 65_F | 1.876 | 1.00 | |
| 24_V | 65_F | 1.872 | 1.00 | |
| 209_V | 225_L | 1.819 | 1.00 | |
| 55_V | 66_Y | 1.788 | 1.00 | |
| 157_E | 161_R | 1.774 | 1.00 | |
| 110_W | 209_V | 1.756 | 1.00 | |
| 138_V | 167_R | 1.746 | 1.00 | |
| 113_A | 141_H | 1.713 | 1.00 | |
| 142_A | 173_S | 1.71 | 1.00 | |
| 138_V | 169_Q | 1.707 | 1.00 | |
| 145_Y | 148_D | 1.7 | 1.00 | |
| 38_K | 51_A | 1.696 | 1.00 | |
| 22_L | 79_L | 1.647 | 1.00 | |
| 69_T | 77_P | 1.63 | 1.00 | |
| 226_K | 233_K | 1.606 | 1.00 | |
| 209_V | 231_M | 1.604 | 1.00 | |
| 10_T | 62_D | 1.591 | 1.00 | |
| 216_Q | 220_D | 1.589 | 1.00 | |
| 35_Q | 96_G | 1.588 | 1.00 | |
| 223_Q | 227_E | 1.57 | 1.00 | |
| 108_T | 138_V | 1.568 | 1.00 | |
| 17_D | 147_A | 1.567 | 1.00 | |
| 112_L | 221_T | 1.549 | 1.00 | |
| 12_V | 83_K | 1.544 | 1.00 | |
| 114_T | 217_M | 1.534 | 1.00 | |
| 136_N | 167_R | 1.487 | 1.00 | |
| 211_L | 221_T | 1.487 | 1.00 | |
| 108_T | 207_S | 1.483 | 1.00 | |
| 39_L | 65_F | 1.482 | 1.00 | |
| 9_V | 24_V | 1.464 | 1.00 | |
| 69_T | 80_A | 1.453 | 1.00 | |
| 118_I | 139_L | 1.443 | 1.00 | |
| 149_L | 172_V | 1.442 | 1.00 | |
| 12_V | 84_P | 1.441 | 1.00 | |
| 190_E | 227_E | 1.431 | 1.00 | |
| 111_M | 121_Y | 1.427 | 1.00 | |
| 111_M | 125_L | 1.405 | 0.99 | |
| 142_A | 217_M | 1.404 | 0.99 | |
| 37_T | 90_V | 1.403 | 0.99 | |
| 187_A | 191_S | 1.401 | 0.99 | |
| 211_L | 218_V | 1.35 | 0.99 | |
| 59_D | 130_D | 1.343 | 0.99 | |
| 112_L | 217_M | 1.334 | 0.99 | |
| 107_E | 208_H | 1.33 | 0.99 | |
| 21_S | 66_Y | 1.317 | 0.99 | |
| 184_R | 216_Q | 1.298 | 0.99 | |
| 146_A | 172_V | 1.292 | 0.99 | |
| 173_S | 184_R | 1.287 | 0.99 | |
| 149_L | 152_L | 1.265 | 0.99 | |
| 187_A | 190_E | 1.258 | 0.99 | |
| 79_L | 82_L | 1.244 | 0.98 | |
| 121_Y | 139_L | 1.242 | 0.98 | |
| 224_L | 227_E | 1.232 | 0.98 | |
| 146_A | 175_E | 1.232 | 0.98 | |
| 12_V | 22_L | 1.226 | 0.98 | |
| 18_A | 68_V | 1.224 | 0.98 | |
| 13_Q | 23_T | 1.22 | 0.98 | |
| 66_Y | 150_S | 1.213 | 0.98 | |
| 107_E | 206_T | 1.211 | 0.98 | |
| 33_A | 127_L | 1.195 | 0.98 | |
| 25_H | 62_D | 1.182 | 0.98 | |
| 9_V | 22_L | 1.182 | 0.98 | |
| 67_L | 79_L | 1.162 | 0.97 | |
| 31_F | 54_Y | 1.157 | 0.97 | |
| 169_Q | 181_L | 1.155 | 0.97 | |
| 18_A | 148_D | 1.145 | 0.97 | |
| 73_G | 76_S | 1.138 | 0.97 | |
| 41_L | 75_L | 1.132 | 0.97 | |
| 125_L | 137_L | 1.131 | 0.97 | |
| 113_A | 139_L | 1.128 | 0.97 | |
| 222_Q | 226_K | 1.126 | 0.97 | |
| 19_L | 116_T | 1.112 | 0.96 | |
| 219_R | 223_Q | 1.101 | 0.96 | |
| 21_S | 151_Y | 1.098 | 0.96 | |
| 181_L | 191_S | 1.097 | 0.96 | |
| 111_M | 124_I | 1.09 | 0.96 | |
| 37_T | 54_Y | 1.083 | 0.96 | |
| 122_L | 126_Q | 1.08 | 0.95 | |
| 215_P | 219_R | 1.077 | 0.95 | |
| 122_L | 154_L | 1.069 | 0.95 | |
| 142_A | 183_G | 1.068 | 0.95 | |
| 15_W | 66_Y | 1.058 | 0.95 | |
| 141_H | 150_S | 1.057 | 0.95 | |
| 149_L | 170_T | 1.051 | 0.94 | |
| 188_L | 191_S | 1.048 | 0.94 | |
| 69_T | 81_A | 1.045 | 0.94 | |
| 129_K | 162_Y | 1.034 | 0.94 | |
| 144_R | 173_S | 1.028 | 0.94 | |
| 57_S | 126_Q | 1.021 | 0.93 | |
| 146_A | 152_L | 1.014 | 0.93 | |
| 142_A | 185_I | 1.011 | 0.93 | |
| 67_L | 80_A | 1.01 | 0.93 | |
| 39_L | 79_L | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1fdrA | 1 | 0.9919 | 100 | 0.172 | Contact Map | 0.815 |
| 4fk8A | 2 | 0.9839 | 100 | 0.174 | Contact Map | 0.743 |
| 2bgiA | 1 | 0.9839 | 100 | 0.19 | Contact Map | 0.778 |
| 1gvhA | 1 | 0.9274 | 100 | 0.192 | Contact Map | 0.76 |
| 4b4dA | 1 | 0.9839 | 100 | 0.195 | Contact Map | 0.805 |
| 1cqxA | 2 | 0.9234 | 100 | 0.2 | Contact Map | 0.782 |
| 2qdxA | 1 | 0.9798 | 100 | 0.2 | Contact Map | 0.756 |
| 1tvcA | 1 | 0.9194 | 100 | 0.207 | Contact Map | 0.514 |
| 4g1vA | 1 | 0.8992 | 100 | 0.208 | Contact Map | 0.805 |
| 1krhA | 2 | 0.9113 | 100 | 0.213 | Contact Map | 0.746 |
Sequence Conservation (Image Generated using WebLogo v3)