| UniProt: | P0AEN1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10334 | ||
| Length: | 233 (229) | ||
| Sequences: | 8301 | ||
| Seq/Len: | 36.25 |
| FRE
Paralog alert: 0.73 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: FENR FRE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 105_P | 133_D | 3.411 | 1.00 | |
| 82_L | 85_H | 3.178 | 1.00 | |
| 7_K | 24_V | 2.97 | 1.00 | |
| 7_K | 86_Q | 2.881 | 1.00 | |
| 22_R | 60_F | 2.7 | 1.00 | |
| 9_T | 24_V | 2.692 | 1.00 | |
| 10_S | 22_R | 2.628 | 1.00 | |
| 14_I | 20_R | 2.596 | 1.00 | |
| 123_L | 151_E | 2.53 | 1.00 | |
| 149_L | 153_E | 2.468 | 1.00 | |
| 20_R | 62_E | 2.46 | 1.00 | |
| 13_A | 19_Y | 2.458 | 1.00 | |
| 5_S | 86_Q | 2.438 | 1.00 | |
| 124_T | 128_R | 2.388 | 1.00 | |
| 40_V | 88_V | 2.386 | 1.00 | |
| 8_V | 81_I | 2.352 | 1.00 | |
| 12_E | 20_R | 2.322 | 1.00 | |
| 22_R | 62_E | 2.314 | 1.00 | |
| 10_S | 83_K | 2.287 | 1.00 | |
| 11_V | 19_Y | 2.287 | 1.00 | |
| 110_A | 118_A | 2.229 | 1.00 | |
| 6_C | 89_V | 2.168 | 1.00 | |
| 140_G | 146_L | 2.057 | 1.00 | |
| 67_A | 79_D | 2.032 | 1.00 | |
| 37_L | 63_L | 2.031 | 1.00 | |
| 111_G | 203_R | 2.002 | 1.00 | |
| 6_C | 23_I | 1.999 | 1.00 | |
| 23_I | 63_L | 1.967 | 1.00 | |
| 135_T | 165_V | 1.849 | 1.00 | |
| 52_A | 64_H | 1.833 | 1.00 | |
| 135_T | 163_Q | 1.757 | 1.00 | |
| 216_S | 222_E | 1.746 | 1.00 | |
| 198_I | 214_F | 1.74 | 1.00 | |
| 154_A | 158_K | 1.739 | 1.00 | |
| 107_I | 198_I | 1.735 | 1.00 | |
| 139_G | 169_E | 1.716 | 1.00 | |
| 5_S | 88_V | 1.715 | 1.00 | |
| 142_E | 145_H | 1.685 | 1.00 | |
| 38_M | 48_P | 1.652 | 1.00 | |
| 9_T | 60_F | 1.632 | 1.00 | |
| 67_A | 75_K | 1.624 | 1.00 | |
| 198_I | 220_A | 1.621 | 1.00 | |
| 110_A | 138_W | 1.62 | 1.00 | |
| 105_P | 135_T | 1.579 | 1.00 | |
| 21_V | 77_V | 1.576 | 1.00 | |
| 111_G | 206_M | 1.551 | 1.00 | |
| 115_F | 136_I | 1.525 | 1.00 | |
| 16_D | 144_Q | 1.518 | 1.00 | |
| 109_I | 210_A | 1.515 | 1.00 | |
| 133_D | 163_Q | 1.491 | 1.00 | |
| 105_P | 196_H | 1.484 | 1.00 | |
| 212_D | 217_E | 1.478 | 1.00 | |
| 11_V | 82_L | 1.478 | 1.00 | |
| 35_Q | 94_G | 1.475 | 1.00 | |
| 39_V | 63_L | 1.47 | 1.00 | |
| 200_I | 210_A | 1.446 | 1.00 | |
| 184_T | 188_Q | 1.43 | 1.00 | |
| 8_V | 23_I | 1.424 | 1.00 | |
| 108_L | 122_L | 1.42 | 1.00 | |
| 205_E | 209_I | 1.402 | 0.99 | |
| 108_L | 118_A | 1.402 | 0.99 | |
| 20_R | 64_H | 1.401 | 0.99 | |
| 146_L | 168_V | 1.361 | 0.99 | |
| 37_L | 89_V | 1.355 | 0.99 | |
| 139_G | 206_M | 1.349 | 0.99 | |
| 11_V | 83_K | 1.337 | 0.99 | |
| 104_R | 197_D | 1.332 | 0.99 | |
| 143_E | 168_V | 1.31 | 0.99 | |
| 165_V | 178_R | 1.301 | 0.99 | |
| 11_V | 21_V | 1.286 | 0.99 | |
| 109_I | 206_M | 1.283 | 0.99 | |
| 197_D | 226_F | 1.264 | 0.99 | |
| 104_R | 195_E | 1.261 | 0.99 | |
| 184_T | 187_L | 1.255 | 0.99 | |
| 213_L | 217_E | 1.25 | 0.99 | |
| 71_N | 74_A | 1.249 | 0.99 | |
| 56_D | 127_A | 1.242 | 0.98 | |
| 200_I | 207_A | 1.231 | 0.98 | |
| 146_L | 149_L | 1.202 | 0.98 | |
| 77_V | 81_I | 1.198 | 0.98 | |
| 169_E | 181_T | 1.197 | 0.98 | |
| 12_E | 22_R | 1.191 | 0.98 | |
| 17_T | 145_H | 1.185 | 0.98 | |
| 33_A | 124_T | 1.167 | 0.97 | |
| 8_V | 21_V | 1.156 | 0.97 | |
| 17_T | 66_G | 1.155 | 0.97 | |
| 178_R | 188_Q | 1.149 | 0.97 | |
| 126_L | 159_H | 1.148 | 0.97 | |
| 67_A | 78_M | 1.143 | 0.97 | |
| 110_A | 136_I | 1.141 | 0.97 | |
| 64_H | 147_Y | 1.137 | 0.97 | |
| 143_E | 171_P | 1.134 | 0.97 | |
| 187_L | 217_E | 1.134 | 0.97 | |
| 37_L | 51_M | 1.128 | 0.97 | |
| 211_R | 216_S | 1.124 | 0.97 | |
| 24_V | 60_F | 1.124 | 0.97 | |
| 118_A | 136_I | 1.12 | 0.96 | |
| 18_V | 113_T | 1.118 | 0.96 | |
| 108_L | 121_I | 1.113 | 0.96 | |
| 200_I | 225_L | 1.106 | 0.96 | |
| 119_R | 123_L | 1.103 | 0.96 | |
| 20_R | 148_D | 1.088 | 0.96 | |
| 122_L | 134_I | 1.086 | 0.96 | |
| 208_K | 212_D | 1.067 | 0.95 | |
| 31_F | 51_M | 1.063 | 0.95 | |
| 143_E | 149_L | 1.054 | 0.95 | |
| 138_W | 147_Y | 1.049 | 0.94 | |
| 184_T | 217_E | 1.042 | 0.94 | |
| 119_R | 151_E | 1.041 | 0.94 | |
| 53_S | 123_L | 1.038 | 0.94 | |
| 54_T | 123_L | 1.027 | 0.94 | |
| 146_L | 166_P | 1.027 | 0.94 | |
| 204_F | 208_K | 1.022 | 0.93 | |
| 6_C | 25_P | 1.021 | 0.93 | |
| 41_M | 73_Y | 1.016 | 0.93 | |
| 75_K | 79_D | 1.01 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1qfjA | 4 | 0.9957 | 100 | 0.127 | Contact Map | 0.796 |
| 1tvcA | 1 | 0.9957 | 100 | 0.128 | Contact Map | 0.512 |
| 1krhA | 2 | 0.9828 | 100 | 0.133 | Contact Map | 0.76 |
| 1gvhA | 1 | 0.9914 | 100 | 0.136 | Contact Map | 0.776 |
| 1cqxA | 2 | 0.9871 | 100 | 0.152 | Contact Map | 0.788 |
| 2r6hA | 4 | 0.9785 | 100 | 0.173 | Contact Map | 0.821 |
| 4g1vA | 1 | 0.9571 | 100 | 0.175 | Contact Map | 0.815 |
| 2eixA | 2 | 0.97 | 100 | 0.187 | Contact Map | 0.853 |
| 4eh1A | 2 | 0.9657 | 100 | 0.193 | Contact Map | 0.919 |
| 1fdrA | 1 | 0.97 | 100 | 0.207 | Contact Map | 0.82 |
Sequence Conservation (Image Generated using WebLogo v3)