| UniProt: | P28305 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11493 | ||
| Length: | 269 (267) | ||
| Sequences: | 4122 | ||
| Seq/Len: | 15.44 |
| PABC
Paralog alert: 0.66 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ILVE PABC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 122_T | 246_A | 4.378 | 1.00 | |
| 187_V | 209_L | 3.834 | 1.00 | |
| 186_V | 217_V | 3.742 | 1.00 | |
| 219_V | 225_E | 3.667 | 1.00 | |
| 44_Q | 60_W | 3.009 | 1.00 | |
| 186_V | 215_Q | 2.927 | 1.00 | |
| 198_N | 203_Q | 2.485 | 1.00 | |
| 188_Y | 219_V | 2.475 | 1.00 | |
| 65_Q | 69_T | 2.467 | 1.00 | |
| 174_C | 177_A | 2.254 | 1.00 | |
| 232_M | 244_V | 2.224 | 1.00 | |
| 170_W | 220_Q | 2.224 | 1.00 | |
| 206_I | 216_L | 2.199 | 1.00 | |
| 41_A | 203_Q | 2.155 | 1.00 | |
| 246_A | 251_S | 2.14 | 1.00 | |
| 212_S | 260_Y | 2.109 | 1.00 | |
| 47_Q | 60_W | 2.108 | 1.00 | |
| 5_N | 101_T | 2.063 | 1.00 | |
| 51_Q | 57_C | 2.051 | 1.00 | |
| 46_L | 83_I | 2.029 | 1.00 | |
| 203_Q | 207_R | 2.01 | 1.00 | |
| 32_I | 240_P | 1.966 | 1.00 | |
| 123_L | 174_C | 1.962 | 1.00 | |
| 59_F | 62_Q | 1.925 | 1.00 | |
| 54_M | 156_Q | 1.919 | 1.00 | |
| 178_N | 199_G | 1.904 | 1.00 | |
| 124_A | 159_A | 1.886 | 1.00 | |
| 259_E | 263_P | 1.885 | 1.00 | |
| 263_P | 267_R | 1.872 | 1.00 | |
| 212_S | 264_L | 1.835 | 1.00 | |
| 124_A | 157_T | 1.819 | 1.00 | |
| 25_C | 49_A | 1.81 | 1.00 | |
| 25_C | 50_C | 1.794 | 1.00 | |
| 183_K | 230_D | 1.775 | 1.00 | |
| 50_C | 83_I | 1.769 | 1.00 | |
| 23_D | 85_R | 1.693 | 1.00 | |
| 39_L | 43_I | 1.691 | 1.00 | |
| 182_R | 257_L | 1.68 | 1.00 | |
| 187_V | 214_Y | 1.673 | 1.00 | |
| 18_A | 24_G | 1.667 | 1.00 | |
| 69_T | 72_A | 1.659 | 1.00 | |
| 115_R | 119_E | 1.647 | 1.00 | |
| 153_H | 157_T | 1.615 | 1.00 | |
| 179_L | 232_M | 1.609 | 1.00 | |
| 207_R | 211_Q | 1.603 | 1.00 | |
| 221_A | 225_E | 1.601 | 1.00 | |
| 44_Q | 48_D | 1.595 | 1.00 | |
| 25_C | 46_L | 1.583 | 1.00 | |
| 205_C | 235_C | 1.58 | 1.00 | |
| 121_I | 160_D | 1.558 | 1.00 | |
| 40_S | 64_E | 1.554 | 1.00 | |
| 48_D | 51_Q | 1.55 | 1.00 | |
| 123_L | 244_V | 1.55 | 1.00 | |
| 24_G | 142_L | 1.54 | 1.00 | |
| 38_L | 204_F | 1.52 | 1.00 | |
| 66_E | 102_R | 1.511 | 1.00 | |
| 55_I | 100_A | 1.484 | 1.00 | |
| 41_A | 207_R | 1.482 | 1.00 | |
| 55_I | 83_I | 1.456 | 1.00 | |
| 181_W | 221_A | 1.45 | 1.00 | |
| 174_C | 234_I | 1.448 | 1.00 | |
| 202_R | 218_E | 1.439 | 1.00 | |
| 189_T | 202_R | 1.433 | 1.00 | |
| 232_M | 247_C | 1.426 | 1.00 | |
| 125_L | 223_L | 1.423 | 1.00 | |
| 180_F | 235_C | 1.413 | 1.00 | |
| 227_L | 250_V | 1.408 | 1.00 | |
| 180_F | 233_V | 1.397 | 0.99 | |
| 40_S | 44_Q | 1.363 | 0.99 | |
| 260_Y | 264_L | 1.334 | 0.99 | |
| 125_L | 248_G | 1.328 | 0.99 | |
| 65_Q | 68_K | 1.328 | 0.99 | |
| 170_W | 222_S | 1.315 | 0.99 | |
| 231_E | 255_A | 1.313 | 0.99 | |
| 181_W | 229_A | 1.306 | 0.99 | |
| 29_A | 36_V | 1.305 | 0.99 | |
| 48_D | 198_N | 1.305 | 0.99 | |
| 163_L | 179_L | 1.298 | 0.99 | |
| 181_W | 232_M | 1.29 | 0.99 | |
| 41_A | 44_Q | 1.287 | 0.99 | |
| 123_L | 163_L | 1.27 | 0.99 | |
| 260_Y | 263_P | 1.264 | 0.99 | |
| 66_E | 69_T | 1.262 | 0.99 | |
| 188_Y | 217_V | 1.257 | 0.99 | |
| 231_E | 258_Y | 1.254 | 0.99 | |
| 122_T | 160_D | 1.254 | 0.99 | |
| 161_E | 174_C | 1.252 | 0.99 | |
| 180_F | 189_T | 1.242 | 0.98 | |
| 181_W | 188_Y | 1.238 | 0.98 | |
| 209_L | 214_Y | 1.236 | 0.98 | |
| 180_F | 206_I | 1.228 | 0.98 | |
| 210_A | 215_Q | 1.215 | 0.98 | |
| 122_T | 245_C | 1.202 | 0.98 | |
| 67_M | 104_L | 1.197 | 0.98 | |
| 4_I | 103_I | 1.196 | 0.98 | |
| 41_A | 200_I | 1.192 | 0.98 | |
| 36_V | 39_L | 1.185 | 0.98 | |
| 47_Q | 57_C | 1.185 | 0.98 | |
| 26_F | 144_R | 1.184 | 0.98 | |
| 166_D | 195_A | 1.182 | 0.98 | |
| 49_A | 139_I | 1.181 | 0.98 | |
| 166_D | 170_W | 1.177 | 0.98 | |
| 152_S | 156_Q | 1.156 | 0.97 | |
| 66_E | 70_L | 1.139 | 0.97 | |
| 38_L | 41_A | 1.128 | 0.97 | |
| 182_R | 187_V | 1.111 | 0.96 | |
| 234_I | 244_V | 1.104 | 0.96 | |
| 210_A | 218_E | 1.102 | 0.96 | |
| 255_A | 258_Y | 1.101 | 0.96 | |
| 183_K | 228_Q | 1.092 | 0.96 | |
| 123_L | 234_I | 1.091 | 0.96 | |
| 236_N | 239_M | 1.08 | 0.95 | |
| 202_R | 206_I | 1.074 | 0.95 | |
| 180_F | 202_R | 1.071 | 0.95 | |
| 43_I | 64_E | 1.066 | 0.95 | |
| 188_Y | 221_A | 1.058 | 0.95 | |
| 151_R | 155_E | 1.051 | 0.94 | |
| 150_I | 162_A | 1.042 | 0.94 | |
| 44_Q | 47_Q | 1.041 | 0.94 | |
| 20_Q | 80_K | 1.04 | 0.94 | |
| 191_R | 220_Q | 1.039 | 0.94 | |
| 83_I | 102_R | 1.037 | 0.94 | |
| 163_L | 226_S | 1.036 | 0.94 | |
| 192_L | 202_R | 1.033 | 0.94 | |
| 264_L | 267_R | 1.031 | 0.94 | |
| 190_P | 221_A | 1.021 | 0.93 | |
| 150_I | 164_V | 1.014 | 0.93 | |
| 191_R | 219_V | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1i2kA | 1 | 1 | 100 | 0.08 | Contact Map | 0.742 |
| 2xpfA | 1 | 0.9963 | 100 | 0.098 | Contact Map | 0.756 |
| 1iyeA | 3 | 1 | 100 | 0.122 | Contact Map | 0.835 |
| 2eiyA | 3 | 0.9963 | 100 | 0.128 | Contact Map | 0.794 |
| 4m0jA | 2 | 0.9851 | 100 | 0.132 | Contact Map | 0.764 |
| 3u0gA | 6 | 0.9926 | 100 | 0.136 | Contact Map | 0.847 |
| 3lulA | 2 | 0.9665 | 100 | 0.142 | Contact Map | 0.743 |
| 3daaA | 2 | 0.9814 | 100 | 0.143 | Contact Map | 0.792 |
| 3snoA | 1 | 0.9703 | 100 | 0.148 | Contact Map | 0.66 |
| 4jxuA | 2 | 0.9851 | 100 | 0.154 | Contact Map | 0.81 |
Sequence Conservation (Image Generated using WebLogo v3)