| UniProt: | P27859 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11481 | ||
| Length: | 260 (253) | ||
| Sequences: | 3454 | ||
| Seq/Len: | 13.65 |
| TATD
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: TATD YCFH YJJV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 78_I | 119_D | 3.452 | 1.00 | |
| 96_F | 134_R | 3.385 | 1.00 | |
| 111_V | 141_P | 3.232 | 1.00 | |
| 232_R | 235_H | 2.988 | 1.00 | |
| 114_L | 124_V | 2.732 | 1.00 | |
| 23_C | 222_E | 2.466 | 1.00 | |
| 158_R | 192_L | 2.306 | 1.00 | |
| 50_R | 83_Q | 2.294 | 1.00 | |
| 250_A | 254_T | 2.218 | 1.00 | |
| 149_A | 169_I | 2.204 | 1.00 | |
| 107_E | 134_R | 2.123 | 1.00 | |
| 22_A | 26_D | 2.102 | 1.00 | |
| 14_A | 17_R | 2.074 | 1.00 | |
| 133_E | 137_T | 2.015 | 1.00 | |
| 140_E | 163_A | 1.967 | 1.00 | |
| 246_A | 250_A | 1.961 | 1.00 | |
| 81_A | 89_I | 1.939 | 1.00 | |
| 230_L | 241_A | 1.915 | 1.00 | |
| 128_C | 135_F | 1.904 | 1.00 | |
| 195_A | 247_T | 1.879 | 1.00 | |
| 162_Q | 166_A | 1.875 | 1.00 | |
| 58_T | 88_A | 1.864 | 1.00 | |
| 239_E | 244_L | 1.85 | 1.00 | |
| 115_R | 142_W | 1.806 | 1.00 | |
| 92_C | 124_V | 1.805 | 1.00 | |
| 16_D | 220_R | 1.804 | 1.00 | |
| 187_R | 232_R | 1.803 | 1.00 | |
| 18_D | 51_Q | 1.758 | 1.00 | |
| 195_A | 239_E | 1.75 | 1.00 | |
| 190_L | 233_I | 1.748 | 1.00 | |
| 31_G | 253_K | 1.744 | 1.00 | |
| 195_A | 237_R | 1.714 | 1.00 | |
| 4_I | 252_V | 1.705 | 1.00 | |
| 231_Q | 241_A | 1.692 | 1.00 | |
| 173_I | 190_L | 1.691 | 1.00 | |
| 92_C | 113_Q | 1.664 | 1.00 | |
| 6_V | 32_L | 1.663 | 1.00 | |
| 1_M | 226_L | 1.661 | 1.00 | |
| 158_R | 162_Q | 1.63 | 1.00 | |
| 140_E | 167_H | 1.608 | 1.00 | |
| 170_Y | 197_K | 1.601 | 1.00 | |
| 110_F | 135_F | 1.588 | 1.00 | |
| 58_T | 125_F | 1.583 | 1.00 | |
| 184_L | 188_E | 1.574 | 1.00 | |
| 227_P | 231_Q | 1.56 | 1.00 | |
| 163_A | 166_A | 1.554 | 1.00 | |
| 150_V | 255_L | 1.548 | 1.00 | |
| 188_E | 191_P | 1.52 | 1.00 | |
| 249_D | 252_V | 1.516 | 1.00 | |
| 47_K | 51_Q | 1.506 | 1.00 | |
| 177_V | 233_I | 1.504 | 1.00 | |
| 2_F | 31_G | 1.502 | 1.00 | |
| 111_V | 142_W | 1.5 | 1.00 | |
| 6_V | 204_A | 1.494 | 1.00 | |
| 112_A | 115_R | 1.489 | 1.00 | |
| 57_S | 86_V | 1.488 | 1.00 | |
| 162_Q | 192_L | 1.487 | 1.00 | |
| 25_F | 54_S | 1.473 | 1.00 | |
| 157_T | 160_E | 1.455 | 1.00 | |
| 36_G | 42_S | 1.451 | 1.00 | |
| 43_Q | 76_A | 1.448 | 1.00 | |
| 107_E | 137_T | 1.44 | 1.00 | |
| 96_F | 107_E | 1.439 | 1.00 | |
| 187_R | 236_W | 1.428 | 1.00 | |
| 108_R | 112_A | 1.424 | 1.00 | |
| 49_A | 57_S | 1.393 | 0.99 | |
| 161_M | 171_I | 1.391 | 0.99 | |
| 2_F | 249_D | 1.391 | 0.99 | |
| 240_D | 243_W | 1.39 | 0.99 | |
| 9_T | 41_E | 1.37 | 0.99 | |
| 200_I | 230_L | 1.368 | 0.99 | |
| 199_L | 255_L | 1.362 | 0.99 | |
| 153_C | 174_T | 1.361 | 0.99 | |
| 78_I | 120_L | 1.354 | 0.99 | |
| 173_I | 198_L | 1.348 | 0.99 | |
| 35_T | 125_F | 1.346 | 0.99 | |
| 1_M | 230_L | 1.34 | 0.99 | |
| 137_T | 141_P | 1.337 | 0.99 | |
| 81_A | 120_L | 1.337 | 0.99 | |
| 231_Q | 235_H | 1.335 | 0.99 | |
| 31_G | 56_W | 1.334 | 0.99 | |
| 151_L | 164_C | 1.33 | 0.99 | |
| 248_T | 252_V | 1.329 | 0.99 | |
| 111_V | 138_L | 1.328 | 0.99 | |
| 121_N | 148_G | 1.324 | 0.99 | |
| 243_W | 246_A | 1.314 | 0.99 | |
| 165_V | 197_K | 1.307 | 0.99 | |
| 184_L | 187_R | 1.304 | 0.99 | |
| 24_A | 32_L | 1.298 | 0.99 | |
| 2_F | 33_L | 1.298 | 0.99 | |
| 128_C | 132_H | 1.283 | 0.99 | |
| 38_N | 41_E | 1.273 | 0.99 | |
| 136_M | 163_A | 1.256 | 0.99 | |
| 110_F | 126_M | 1.252 | 0.99 | |
| 118_A | 142_W | 1.252 | 0.99 | |
| 249_D | 253_K | 1.25 | 0.99 | |
| 194_P | 197_K | 1.245 | 0.98 | |
| 107_E | 138_L | 1.238 | 0.98 | |
| 47_K | 50_R | 1.232 | 0.98 | |
| 107_E | 111_V | 1.225 | 0.98 | |
| 13_F | 220_R | 1.202 | 0.98 | |
| 64_H | 98_R | 1.197 | 0.98 | |
| 179_D | 208_L | 1.196 | 0.98 | |
| 103_P | 107_E | 1.175 | 0.98 | |
| 150_V | 256_F | 1.168 | 0.97 | |
| 21_V | 32_L | 1.157 | 0.97 | |
| 212_L | 228_H | 1.157 | 0.97 | |
| 233_I | 244_L | 1.156 | 0.97 | |
| 102_T | 105_E | 1.155 | 0.97 | |
| 133_E | 163_A | 1.154 | 0.97 | |
| 170_Y | 254_T | 1.152 | 0.97 | |
| 76_A | 79_E | 1.15 | 0.97 | |
| 115_R | 119_D | 1.137 | 0.97 | |
| 200_I | 233_I | 1.114 | 0.96 | |
| 34_I | 45_A | 1.114 | 0.96 | |
| 16_D | 19_D | 1.105 | 0.96 | |
| 226_L | 229_I | 1.093 | 0.96 | |
| 126_M | 151_L | 1.093 | 0.96 | |
| 200_I | 226_L | 1.086 | 0.96 | |
| 50_R | 85_E | 1.084 | 0.96 | |
| 45_A | 57_S | 1.083 | 0.96 | |
| 171_I | 193_I | 1.076 | 0.95 | |
| 190_L | 237_R | 1.067 | 0.95 | |
| 193_I | 198_L | 1.066 | 0.95 | |
| 21_V | 52_Y | 1.066 | 0.95 | |
| 228_H | 231_Q | 1.057 | 0.95 | |
| 159_E | 162_Q | 1.054 | 0.95 | |
| 104_E | 108_R | 1.053 | 0.95 | |
| 133_E | 160_E | 1.05 | 0.94 | |
| 18_D | 52_Y | 1.046 | 0.94 | |
| 230_L | 248_T | 1.043 | 0.94 | |
| 66_S | 109_A | 1.041 | 0.94 | |
| 239_E | 243_W | 1.037 | 0.94 | |
| 33_L | 87_V | 1.035 | 0.94 | |
| 132_H | 160_E | 1.034 | 0.94 | |
| 96_F | 103_P | 1.034 | 0.94 | |
| 74_E | 112_A | 1.034 | 0.94 | |
| 132_H | 156_G | 1.021 | 0.93 | |
| 19_D | 23_C | 1.019 | 0.93 | |
| 39_L | 42_S | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3e2vA | 2 | 0.9885 | 100 | 0.137 | Contact Map | 0.789 |
| 3ipwA | 1 | 0.9731 | 100 | 0.216 | Contact Map | 0.777 |
| 2xioA | 1 | 0.9731 | 100 | 0.29 | Contact Map | 0.777 |
| 1j6oA | 1 | 0.9808 | 100 | 0.292 | Contact Map | 0.782 |
| 3gg7A | 1 | 0.9308 | 100 | 0.335 | Contact Map | 0.588 |
| 1xwyA | 1 | 0.9808 | 100 | 0.351 | Contact Map | 0.767 |
| 3rcmA | 1 | 0.9846 | 100 | 0.352 | Contact Map | 0.753 |
| 2gzxA | 2 | 0.9808 | 100 | 0.36 | Contact Map | 0.84 |
| 1zzmA | 1 | 0.9731 | 100 | 0.375 | Contact Map | 0.737 |
| 2y1hA | 2 | 0.9577 | 100 | 0.383 | Contact Map | 0.774 |
Sequence Conservation (Image Generated using WebLogo v3)