| UniProt: | P0AFQ7 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12303 | ||
| Length: | 265 (253) | ||
| Sequences: | 3377 | ||
| Seq/Len: | 13.35 |
| YCFH
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: TATD YCFH YJJV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 81_R | 122_E | 3.429 | 1.00 | |
| 99_Y | 137_D | 3.369 | 1.00 | |
| 114_I | 144_E | 3.19 | 1.00 | |
| 230_Y | 233_V | 2.967 | 1.00 | |
| 117_I | 127_V | 2.773 | 1.00 | |
| 28_K | 220_Q | 2.517 | 1.00 | |
| 55_G | 86_E | 2.374 | 1.00 | |
| 161_R | 194_Y | 2.313 | 1.00 | |
| 152_G | 172_F | 2.244 | 1.00 | |
| 248_D | 252_R | 2.214 | 1.00 | |
| 110_Q | 137_D | 2.179 | 1.00 | |
| 19_H | 22_V | 2.129 | 1.00 | |
| 27_A | 31_A | 2.081 | 1.00 | |
| 143_R | 166_K | 2.027 | 1.00 | |
| 136_A | 140_A | 2.011 | 1.00 | |
| 84_A | 92_L | 1.99 | 1.00 | |
| 228_A | 239_V | 1.951 | 1.00 | |
| 197_L | 245_V | 1.931 | 1.00 | |
| 237_V | 242_L | 1.905 | 1.00 | |
| 244_Q | 248_D | 1.904 | 1.00 | |
| 131_T | 138_T | 1.882 | 1.00 | |
| 165_G | 169_D | 1.858 | 1.00 | |
| 63_S | 91_A | 1.851 | 1.00 | |
| 95_T | 127_V | 1.825 | 1.00 | |
| 118_Q | 145_E | 1.799 | 1.00 | |
| 189_R | 230_Y | 1.797 | 1.00 | |
| 192_A | 231_M | 1.765 | 1.00 | |
| 197_L | 237_V | 1.762 | 1.00 | |
| 197_L | 235_K | 1.744 | 1.00 | |
| 23_D | 56_E | 1.735 | 1.00 | |
| 36_F | 251_A | 1.722 | 1.00 | |
| 113_F | 138_T | 1.721 | 1.00 | |
| 229_E | 239_V | 1.719 | 1.00 | |
| 8_C | 37_C | 1.715 | 1.00 | |
| 21_D | 218_E | 1.709 | 1.00 | |
| 3_L | 224_V | 1.698 | 1.00 | |
| 6_S | 250_F | 1.693 | 1.00 | |
| 176_F | 192_A | 1.691 | 1.00 | |
| 95_T | 116_H | 1.681 | 1.00 | |
| 143_R | 170_L | 1.633 | 1.00 | |
| 161_R | 165_G | 1.608 | 1.00 | |
| 63_S | 128_I | 1.606 | 1.00 | |
| 114_I | 145_E | 1.566 | 1.00 | |
| 186_E | 190_D | 1.561 | 1.00 | |
| 173_Y | 199_R | 1.561 | 1.00 | |
| 153_V | 253_L | 1.557 | 1.00 | |
| 225_R | 229_E | 1.556 | 1.00 | |
| 4_V | 36_F | 1.539 | 1.00 | |
| 166_K | 169_D | 1.522 | 1.00 | |
| 190_D | 193_R | 1.519 | 1.00 | |
| 247_T | 250_F | 1.515 | 1.00 | |
| 8_C | 206_S | 1.514 | 1.00 | |
| 99_Y | 110_Q | 1.508 | 1.00 | |
| 30_A | 59_N | 1.507 | 1.00 | |
| 115_H | 118_Q | 1.498 | 1.00 | |
| 180_V | 231_M | 1.489 | 1.00 | |
| 110_Q | 140_A | 1.461 | 1.00 | |
| 48_L | 79_D | 1.453 | 1.00 | |
| 165_G | 194_Y | 1.448 | 1.00 | |
| 3_L | 228_A | 1.431 | 1.00 | |
| 4_V | 247_T | 1.43 | 1.00 | |
| 41_A | 47_Y | 1.43 | 1.00 | |
| 52_D | 56_E | 1.422 | 1.00 | |
| 160_D | 163_T | 1.419 | 1.00 | |
| 164_A | 174_I | 1.402 | 0.99 | |
| 111_E | 115_H | 1.401 | 0.99 | |
| 62_F | 89_V | 1.39 | 0.99 | |
| 189_R | 234_L | 1.389 | 0.99 | |
| 11_D | 46_G | 1.375 | 0.99 | |
| 238_A | 241_E | 1.371 | 0.99 | |
| 156_C | 177_S | 1.365 | 0.99 | |
| 201_L | 253_L | 1.359 | 0.99 | |
| 202_V | 228_A | 1.355 | 0.99 | |
| 140_A | 144_E | 1.353 | 0.99 | |
| 81_R | 123_L | 1.349 | 0.99 | |
| 154_L | 167_L | 1.348 | 0.99 | |
| 84_A | 123_L | 1.34 | 0.99 | |
| 176_F | 200_L | 1.338 | 0.99 | |
| 40_V | 128_I | 1.33 | 0.99 | |
| 229_E | 233_V | 1.324 | 0.99 | |
| 114_I | 141_I | 1.321 | 0.99 | |
| 4_V | 38_L | 1.31 | 0.99 | |
| 29_A | 37_C | 1.302 | 0.99 | |
| 36_F | 61_V | 1.297 | 0.99 | |
| 168_L | 199_R | 1.297 | 0.99 | |
| 124_N | 151_G | 1.296 | 0.99 | |
| 246_T | 250_F | 1.292 | 0.99 | |
| 241_E | 244_Q | 1.285 | 0.99 | |
| 131_T | 135_R | 1.281 | 0.99 | |
| 43_T | 46_G | 1.262 | 0.99 | |
| 139_L | 166_K | 1.255 | 0.99 | |
| 182_F | 210_A | 1.254 | 0.99 | |
| 110_Q | 141_I | 1.251 | 0.99 | |
| 121_R | 145_E | 1.247 | 0.99 | |
| 18_L | 218_E | 1.235 | 0.98 | |
| 113_F | 129_V | 1.233 | 0.98 | |
| 69_L | 101_Y | 1.222 | 0.98 | |
| 196_P | 199_R | 1.22 | 0.98 | |
| 54_V | 62_F | 1.217 | 0.98 | |
| 186_E | 189_R | 1.216 | 0.98 | |
| 110_Q | 114_I | 1.202 | 0.98 | |
| 247_T | 251_A | 1.186 | 0.98 | |
| 173_Y | 252_R | 1.182 | 0.98 | |
| 136_A | 166_K | 1.18 | 0.98 | |
| 231_M | 242_L | 1.175 | 0.98 | |
| 118_Q | 122_E | 1.174 | 0.98 | |
| 26_L | 37_C | 1.164 | 0.97 | |
| 105_T | 108_R | 1.156 | 0.97 | |
| 52_D | 55_G | 1.156 | 0.97 | |
| 153_V | 254_F | 1.15 | 0.97 | |
| 21_D | 24_D | 1.146 | 0.97 | |
| 106_K | 110_Q | 1.144 | 0.97 | |
| 214_H | 226_D | 1.144 | 0.97 | |
| 38_L | 90_V | 1.141 | 0.97 | |
| 39_A | 50_M | 1.098 | 0.96 | |
| 79_D | 82_R | 1.093 | 0.96 | |
| 202_V | 231_M | 1.089 | 0.96 | |
| 224_V | 227_V | 1.089 | 0.96 | |
| 24_D | 28_K | 1.089 | 0.96 | |
| 162_E | 165_G | 1.081 | 0.95 | |
| 174_I | 195_V | 1.08 | 0.95 | |
| 226_D | 229_E | 1.078 | 0.95 | |
| 129_V | 154_L | 1.067 | 0.95 | |
| 55_G | 88_G | 1.065 | 0.95 | |
| 136_A | 163_T | 1.062 | 0.95 | |
| 107_V | 111_E | 1.06 | 0.95 | |
| 192_A | 235_K | 1.057 | 0.95 | |
| 26_L | 57_R | 1.055 | 0.95 | |
| 195_V | 200_L | 1.055 | 0.95 | |
| 135_R | 163_T | 1.054 | 0.95 | |
| 71_Q | 112_S | 1.046 | 0.94 | |
| 202_V | 224_V | 1.044 | 0.94 | |
| 237_V | 241_E | 1.034 | 0.94 | |
| 12_G | 17_S | 1.034 | 0.94 | |
| 23_D | 57_R | 1.03 | 0.94 | |
| 102_T | 106_K | 1.017 | 0.93 | |
| 135_R | 159_E | 1.016 | 0.93 | |
| 4_V | 250_F | 1.008 | 0.93 | |
| 99_Y | 106_K | 1.008 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3e2vA | 2 | 0.9623 | 100 | 0.182 | Contact Map | 0.787 |
| 3ipwA | 1 | 0.9585 | 100 | 0.251 | Contact Map | 0.78 |
| 2xioA | 1 | 0.9887 | 100 | 0.327 | Contact Map | 0.774 |
| 1j6oA | 1 | 0.966 | 100 | 0.332 | Contact Map | 0.783 |
| 3gg7A | 1 | 0.9434 | 100 | 0.354 | Contact Map | 0.593 |
| 3rcmA | 1 | 0.9887 | 100 | 0.374 | Contact Map | 0.76 |
| 1xwyA | 1 | 0.9623 | 100 | 0.385 | Contact Map | 0.765 |
| 1yixA | 2 | 1 | 100 | 0.388 | Contact Map | 0.769 |
| 2gzxA | 2 | 0.9849 | 100 | 0.394 | Contact Map | 0.848 |
| 1zzmA | 1 | 0.9547 | 100 | 0.4 | Contact Map | 0.729 |
Sequence Conservation (Image Generated using WebLogo v3)