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OPENSEQ.org
YCHE - UPF0056 membrane protein YhcE
UniProt: P25743 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11342
Length: 215 (208)
Sequences: 1243
Seq/Len: 5.98
YCHE
Paralog alert: 0.53 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MARC YCHE YHGN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
81_I 203_V 3.217 1.00
78_S 200_E 3.175 1.00
203_V 209_I 3.106 1.00
58_L 133_A 3.027 1.00
89_T 92_M 2.6 1.00
39_T 42_A 2.282 1.00
165_W 169_R 2.27 1.00
55_A 161_A 2.204 1.00
57_I 125_L 2.013 1.00
52_L 56_I 1.975 1.00
55_A 59_W 1.937 1.00
48_L 165_W 1.772 1.00
85_I 88_V 1.752 1.00
53_S 120_V 1.738 1.00
55_A 158_A 1.729 1.00
15_F 159_L 1.725 1.00
162_L 166_G 1.713 1.00
77_D 208_G 1.696 1.00
66_D 70_Q 1.676 1.00
62_L 137_T 1.671 1.00
200_E 204_T 1.652 1.00
31_F 35_T 1.645 1.00
58_L 137_T 1.64 1.00
51_N 161_A 1.63 1.00
81_I 209_I 1.62 1.00
94_M 191_G 1.58 0.99
88_V 202_I 1.554 0.99
59_W 158_A 1.529 0.99
94_M 190_M 1.522 0.99
88_V 198_G 1.518 0.99
57_I 129_A 1.505 0.99
23_N 26_G 1.463 0.99
15_F 163_C 1.46 0.99
179_R 182_G 1.458 0.99
31_F 47_N 1.458 0.99
22_V 160_F 1.428 0.98
11_Y 155_V 1.4 0.98
137_T 157_I 1.397 0.98
91_A 198_G 1.392 0.98
77_D 80_R 1.35 0.98
54_V 161_A 1.348 0.98
14_F 140_W 1.332 0.97
78_S 203_V 1.329 0.97
94_M 187_T 1.313 0.97
81_I 199_I 1.312 0.97
57_I 124_A 1.297 0.97
20_A 72_F 1.279 0.96
20_A 23_N 1.272 0.96
63_F 154_F 1.262 0.96
69_L 75_S 1.261 0.96
14_F 156_A 1.258 0.96
58_L 129_A 1.244 0.96
22_V 133_A 1.243 0.96
141_G 153_F 1.242 0.96
173_W 176_R 1.24 0.95
207_K 210_F 1.223 0.95
105_N 108_E 1.219 0.95
51_N 164_C 1.218 0.95
26_G 29_P 1.214 0.95
44_N 169_R 1.204 0.94
75_S 200_E 1.202 0.94
86_L 90_I 1.2 0.94
69_L 196_A 1.199 0.94
59_W 154_F 1.178 0.94
158_A 162_L 1.175 0.93
53_S 124_A 1.164 0.93
11_Y 156_A 1.125 0.91
119_G 124_A 1.113 0.91
31_F 171_A 1.106 0.90
51_N 165_W 1.1 0.90
27_I 168_F 1.094 0.90
23_N 29_P 1.092 0.90
31_F 123_L 1.085 0.89
166_G 170_M 1.083 0.89
29_P 32_I 1.077 0.89
86_L 127_L 1.068 0.88
160_F 163_C 1.068 0.88
203_V 206_I 1.067 0.88
58_L 157_I 1.067 0.88
88_V 195_M 1.065 0.88
86_L 195_M 1.061 0.88
19_F 167_L 1.057 0.88
97_G 188_R 1.056 0.88
27_I 127_L 1.054 0.87
23_N 190_M 1.054 0.87
79_F 192_L 1.054 0.87
45_K 49_T 1.05 0.87
91_A 195_M 1.049 0.87
49_T 117_S 1.049 0.87
50_A 54_V 1.043 0.87
39_T 45_K 1.022 0.85
11_Y 15_F 1.018 0.85
35_T 39_T 1.01 0.84
69_L 83_G 1.005 0.84
84_G 205_G 1.002 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2cfqA10.52098.80.957Contact Map0.372
4ainA30.53497.40.958Contact Map0.401
1pw4A10.520940.963Contact Map0.198
2xutA30.54423.80.964Contact Map0.26
4c7rA30.55352.60.966Contact Map0.4
2lx0A10.14882.60.966Contact Map0.788
1hjiB10.120920.968Contact Map0.471
1jb0M10.14421.90.969Contact Map0.569
4ldsA20.53491.30.972Contact Map0.333
3bz1X10.19071.20.972Contact Map0.248
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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