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OPENSEQ.org
MARC - UPF0056 inner membrane protein MarC
UniProt: P0AEY1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11637
Length: 221 (213)
Sequences: 1256
Seq/Len: 5.90
MARC
Paralog alert: 0.53 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MARC YCHE YHGN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
78_I 210_I 3.362 1.00
75_G 207_Q 3.351 1.00
210_I 216_I 3.255 1.00
55_M 134_T 2.991 1.00
86_F 89_F 2.802 1.00
36_N 39_E 2.606 1.00
172_W 176_R 2.096 1.00
52_F 56_M 2.02 1.00
45_L 172_W 1.971 1.00
52_F 168_A 1.926 1.00
54_I 126_M 1.908 1.00
82_L 85_A 1.872 1.00
85_A 209_I 1.866 1.00
59_Y 138_I 1.854 1.00
49_V 53_A 1.824 1.00
74_P 215_E 1.794 1.00
169_V 173_G 1.772 1.00
207_Q 211_N 1.766 1.00
78_I 216_I 1.758 1.00
50_Y 121_F 1.692 1.00
91_M 198_G 1.685 1.00
63_Q 67_D 1.658 1.00
28_F 32_A 1.642 1.00
55_M 138_I 1.601 0.99
186_G 189_G 1.586 0.99
12_L 166_L 1.549 0.99
91_M 197_M 1.526 0.99
54_I 130_A 1.519 0.99
85_A 205_G 1.512 0.99
48_S 168_A 1.505 0.99
74_P 77_R 1.495 0.99
28_F 44_S 1.482 0.99
51_V 168_A 1.455 0.99
20_N 23_T 1.426 0.98
17_P 20_N 1.422 0.98
52_F 165_F 1.415 0.98
78_I 206_V 1.404 0.98
88_G 205_G 1.379 0.98
91_M 194_S 1.378 0.98
41_N 176_R 1.349 0.98
75_G 210_I 1.343 0.97
54_I 125_A 1.341 0.97
23_T 26_A 1.33 0.97
12_L 170_I 1.322 0.97
17_P 69_F 1.299 0.97
50_Y 125_A 1.285 0.96
19_A 134_T 1.279 0.96
56_M 165_F 1.279 0.96
19_A 167_V 1.274 0.96
83_I 87_I 1.269 0.96
55_M 130_A 1.245 0.95
24_T 175_L 1.238 0.95
66_M 203_C 1.237 0.95
107_K 110_E 1.219 0.95
138_I 164_F 1.214 0.95
66_M 72_S 1.21 0.94
26_A 29_L 1.172 0.93
120_A 125_A 1.169 0.93
28_F 178_S 1.164 0.93
55_M 164_F 1.162 0.93
48_S 171_L 1.162 0.93
32_A 36_N 1.154 0.92
85_A 202_V 1.152 0.92
15_L 138_I 1.147 0.92
15_L 19_A 1.143 0.92
36_N 42_R 1.124 0.91
180_A 183_R 1.124 0.91
210_I 213_I 1.121 0.91
46_M 118_N 1.112 0.91
24_T 128_S 1.106 0.90
47_A 51_V 1.106 0.90
173_G 177_S 1.101 0.90
28_F 124_L 1.1 0.90
88_G 202_V 1.096 0.90
16_L 174_S 1.092 0.89
82_L 209_I 1.091 0.89
7_A 10_L 1.088 0.89
90_R 95_Q 1.087 0.89
20_N 26_A 1.078 0.89
83_I 128_S 1.077 0.89
24_T 83_I 1.059 0.87
72_S 207_Q 1.055 0.87
66_M 80_G 1.046 0.87
45_L 176_R 1.04 0.86
20_N 197_M 1.033 0.86
76_L 199_F 1.031 0.85
167_V 170_I 1.03 0.85
37_S 40_R 1.028 0.85
42_R 46_M 1.021 0.85
59_Y 142_A 1.013 0.84
130_A 193_I 1.009 0.84
48_S 172_W 1.007 0.84
134_T 164_F 1.006 0.84
17_P 199_F 1.005 0.83
214_L 217_I 1.002 0.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2xutA30.50684.90.961Contact Map0.263
4ldsA20.52494.70.962Contact Map0.292
4j05A20.54753.60.964Contact Map0.246
2cfqA10.49323.50.964Contact Map0.325
2lx0A10.14482.90.965Contact Map0.751
3arcX20.17192.80.966Contact Map0.559
1hjiB10.11762.60.966Contact Map0.427
1pw4A10.49322.40.967Contact Map0.242
3bz1X10.17651.80.969Contact Map0.353
3wdoA10.66521.50.97Contact Map0.387
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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