| UniProt: | P25536 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11298 | ||
| Length: | 197 (186) | ||
| Sequences: | 2581 | ||
| Seq/Len: | 13.88 |
| YHDE
Paralog alert: 0.44 [within 20: 0.00] - ratio of genomes with paralogs Cluster includes: YCEF YHDE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 94_R | 131_D | 3.598 | 1.00 | |
| 86_A | 139_A | 3.259 | 1.00 | |
| 78_E | 95_K | 3.232 | 1.00 | |
| 76_N | 99_Q | 3.177 | 1.00 | |
| 100_T | 125_T | 3.125 | 1.00 | |
| 14_Q | 18_A | 2.898 | 1.00 | |
| 90_A | 135_A | 2.749 | 1.00 | |
| 88_H | 91_Q | 2.637 | 1.00 | |
| 49_A | 108_A | 2.491 | 1.00 | |
| 31_I | 51_E | 2.32 | 1.00 | |
| 123_D | 164_N | 2.271 | 1.00 | |
| 122_T | 170_V | 2.258 | 1.00 | |
| 102_Q | 123_D | 2.06 | 1.00 | |
| 125_T | 161_R | 2.031 | 1.00 | |
| 102_Q | 121_V | 2.023 | 1.00 | |
| 50_R | 54_R | 1.986 | 1.00 | |
| 46_V | 119_L | 1.953 | 1.00 | |
| 138_V | 144_L | 1.947 | 1.00 | |
| 122_T | 169_A | 1.946 | 1.00 | |
| 90_A | 138_V | 1.945 | 1.00 | |
| 97_S | 129_L | 1.901 | 1.00 | |
| 130_T | 133_D | 1.83 | 1.00 | |
| 86_A | 138_V | 1.812 | 1.00 | |
| 39_E | 47_R | 1.811 | 1.00 | |
| 125_T | 162_K | 1.753 | 1.00 | |
| 156_G | 159_F | 1.751 | 1.00 | |
| 173_L | 178_T | 1.743 | 1.00 | |
| 120_V | 169_A | 1.705 | 1.00 | |
| 84_R | 88_H | 1.698 | 1.00 | |
| 100_T | 123_D | 1.695 | 1.00 | |
| 14_Q | 24_F | 1.691 | 1.00 | |
| 3_S | 25_E | 1.68 | 1.00 | |
| 90_A | 134_I | 1.654 | 1.00 | |
| 129_L | 134_I | 1.64 | 1.00 | |
| 97_S | 131_D | 1.553 | 1.00 | |
| 9_G | 28_V | 1.529 | 1.00 | |
| 142_E | 154_G | 1.506 | 1.00 | |
| 86_A | 90_A | 1.488 | 1.00 | |
| 97_S | 128_T | 1.481 | 1.00 | |
| 4_L | 67_L | 1.462 | 1.00 | |
| 101_H | 150_Y | 1.462 | 1.00 | |
| 50_R | 117_D | 1.437 | 1.00 | |
| 120_V | 177_E | 1.435 | 1.00 | |
| 89_A | 143_P | 1.433 | 1.00 | |
| 44_Y | 72_I | 1.414 | 1.00 | |
| 86_A | 144_L | 1.406 | 0.99 | |
| 54_R | 115_I | 1.405 | 0.99 | |
| 15_E | 19_Q | 1.386 | 0.99 | |
| 90_A | 94_R | 1.383 | 0.99 | |
| 67_L | 109_L | 1.377 | 0.99 | |
| 92_M | 149_A | 1.375 | 0.99 | |
| 152_I | 171_V | 1.359 | 0.99 | |
| 53_A | 68_G | 1.359 | 0.99 | |
| 104_M | 121_V | 1.338 | 0.99 | |
| 7_A | 68_G | 1.332 | 0.99 | |
| 75_L | 99_Q | 1.328 | 0.99 | |
| 108_A | 117_D | 1.318 | 0.99 | |
| 74_I | 104_M | 1.261 | 0.99 | |
| 109_L | 181_L | 1.254 | 0.99 | |
| 44_Y | 48_L | 1.252 | 0.99 | |
| 118_C | 181_L | 1.251 | 0.99 | |
| 167_Y | 171_V | 1.251 | 0.99 | |
| 85_D | 88_H | 1.248 | 0.99 | |
| 27_I | 59_Q | 1.245 | 0.98 | |
| 116_L | 184_N | 1.241 | 0.98 | |
| 18_A | 24_F | 1.232 | 0.98 | |
| 29_T | 56_G | 1.225 | 0.98 | |
| 104_M | 119_L | 1.213 | 0.98 | |
| 131_D | 135_A | 1.202 | 0.98 | |
| 80_L | 92_M | 1.195 | 0.98 | |
| 116_L | 181_L | 1.195 | 0.98 | |
| 50_R | 108_A | 1.194 | 0.98 | |
| 118_C | 177_E | 1.192 | 0.98 | |
| 89_A | 149_A | 1.16 | 0.97 | |
| 132_E | 136_G | 1.152 | 0.97 | |
| 127_R | 133_D | 1.15 | 0.97 | |
| 5_Y | 56_G | 1.149 | 0.97 | |
| 146_K | 151_G | 1.134 | 0.97 | |
| 107_V | 118_C | 1.13 | 0.97 | |
| 67_L | 178_T | 1.103 | 0.96 | |
| 12_R | 145_D | 1.099 | 0.96 | |
| 14_Q | 26_R | 1.096 | 0.96 | |
| 94_R | 134_I | 1.093 | 0.96 | |
| 138_V | 143_P | 1.091 | 0.96 | |
| 31_I | 48_L | 1.09 | 0.96 | |
| 107_V | 178_T | 1.085 | 0.96 | |
| 65_P | 109_L | 1.074 | 0.95 | |
| 40_S | 43_Q | 1.054 | 0.95 | |
| 16_L | 173_L | 1.052 | 0.95 | |
| 122_T | 163_I | 1.052 | 0.95 | |
| 75_L | 95_K | 1.048 | 0.94 | |
| 47_R | 51_E | 1.042 | 0.94 | |
| 91_Q | 95_K | 1.041 | 0.94 | |
| 96_L | 150_Y | 1.041 | 0.94 | |
| 45_V | 106_A | 1.026 | 0.94 | |
| 127_R | 176_V | 1.024 | 0.93 | |
| 30_G | 55_A | 1.02 | 0.93 | |
| 50_R | 115_I | 1.017 | 0.93 | |
| 46_V | 117_D | 1.015 | 0.93 | |
| 135_A | 139_A | 1.006 | 0.93 | |
| 158_C | 179_Y | 1.005 | 0.93 | |
| 86_A | 135_A | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ex2A | 2 | 0.9543 | 100 | 0.068 | Contact Map | 0.89 |
| 4jhcA | 2 | 0.9695 | 100 | 0.08 | Contact Map | 0.888 |
| 2p5xA | 2 | 1 | 100 | 0.082 | Contact Map | 0.898 |
| 2amhA | 1 | 0.9391 | 100 | 0.09 | Contact Map | 0.671 |
| 4bnqA | 2 | 0.868 | 99.7 | 0.722 | Contact Map | 0.36 |
| 3tquA | 4 | 0.8579 | 99.5 | 0.762 | Contact Map | 0.408 |
| 1k7kA | 1 | 0.8426 | 97.2 | 0.885 | Contact Map | 0.518 |
| 1v7rA | 1 | 0.7462 | 97.1 | 0.887 | Contact Map | 0.269 |
| 1b78A | 2 | 0.8274 | 96.9 | 0.89 | Contact Map | 0.476 |
| 2carA | 2 | 0.8274 | 91.6 | 0.918 | Contact Map | 0.439 |
Sequence Conservation (Image Generated using WebLogo v3)