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OPENSEQ.org

YCEF - Maf-like protein YceF
UniProt: P0A729 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11438
Length: 194 (189)
Sequences: 2594
Seq/Len: 13.72

YCEF
Paralog alert: 0.45 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YCEF YHDE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
93_R 132_E 3.64 1.00
85_E 140_R 3.284 1.00
75_D 98_N 3.272 1.00
77_E 94_K 3.215 1.00
99_I 126_H 3.166 1.00
14_R 18_E 2.947 1.00
89_R 136_D 2.721 1.00
87_N 90_L 2.55 1.00
49_A 107_A 2.506 1.00
124_D 165_E 2.317 1.00
31_V 51_E 2.258 1.00
123_F 172_L 2.258 1.00
101_T 124_D 2.079 1.00
101_T 122_P 2.07 1.00
126_H 162_E 2.052 1.00
139_V 145_L 1.994 1.00
123_F 171_T 1.976 1.00
46_L 120_V 1.946 1.00
50_Q 54_Q 1.937 1.00
89_R 139_V 1.924 1.00
96_S 130_L 1.907 1.00
131_S 134_E 1.875 1.00
85_E 139_V 1.83 1.00
39_E 47_R 1.829 1.00
157_G 160_L 1.794 1.00
126_H 163_R 1.764 1.00
175_L 180_L 1.75 1.00
121_E 171_T 1.728 1.00
14_R 24_F 1.723 1.00
83_L 87_N 1.702 1.00
99_I 124_D 1.696 1.00
3_K 25_E 1.674 1.00
89_R 135_I 1.635 1.00
130_L 135_I 1.598 1.00
96_S 132_E 1.562 1.00
4_L 66_I 1.555 1.00
143_H 155_G 1.502 1.00
85_E 89_R 1.501 1.00
100_V 151_F 1.483 1.00
9_T 28_A 1.473 1.00
96_S 129_H 1.469 1.00
121_E 179_A 1.465 1.00
88_A 144_P 1.463 1.00
44_L 71_V 1.454 1.00
85_E 145_L 1.444 1.00
54_Q 116_L 1.437 1.00
91_Q 150_S 1.423 1.00
15_A 19_K 1.418 1.00
66_I 108_L 1.415 1.00
89_R 93_R 1.409 1.00
74_L 98_N 1.405 0.99
50_Q 118_T 1.4 0.99
7_A 67_G 1.378 0.99
107_A 118_T 1.373 0.99
103_Y 122_P 1.362 0.99
53_A 67_G 1.352 0.99
153_S 173_V 1.344 0.99
117_Q 186_R 1.294 0.99
108_L 183_M 1.279 0.99
169_P 173_V 1.275 0.99
103_Y 120_V 1.27 0.99
73_V 103_Y 1.263 0.99
27_A 59_R 1.255 0.99
44_L 48_L 1.246 0.98
84_T 87_N 1.245 0.98
119_E 183_M 1.241 0.98
18_E 24_F 1.231 0.98
29_P 56_L 1.216 0.98
132_E 136_D 1.21 0.98
79_T 91_Q 1.21 0.98
128_R 134_E 1.186 0.98
119_E 179_A 1.178 0.98
106_L 119_E 1.176 0.98
147_C 152_K 1.172 0.98
5_I 56_L 1.167 0.97
50_Q 107_A 1.148 0.97
88_A 150_S 1.142 0.97
117_Q 183_M 1.141 0.97
64_L 108_L 1.125 0.97
12_W 146_H 1.119 0.96
14_R 26_C 1.105 0.96
139_V 144_P 1.103 0.96
133_A 137_N 1.097 0.96
106_L 180_L 1.089 0.96
74_L 94_K 1.061 0.95
90_L 94_K 1.059 0.95
16_L 175_L 1.055 0.95
123_F 164_L 1.055 0.95
66_I 180_L 1.055 0.95
31_V 48_L 1.05 0.94
128_R 178_I 1.044 0.94
95_A 151_F 1.044 0.94
45_V 105_G 1.032 0.94
40_S 43_Q 1.03 0.94
47_R 51_E 1.017 0.93
93_R 135_I 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4jhcA20.99481000.008Contact Map0.897
1ex2A20.96911000.023Contact Map0.902
2p5xA20.99481000.038Contact Map0.894
2amhA10.95881000.039Contact Map0.682
4bnqA20.886699.70.709Contact Map0.396
3tquA40.881499.50.753Contact Map0.397
1k7kA10.876396.80.886Contact Map0.538
1v7rA10.76896.60.888Contact Map0.287
1b78A20.840296.40.891Contact Map0.465
1vp2A20.840288.70.919Contact Map0.548

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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