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YGGC - Uncharacterized protein YggC
UniProt: P11664 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11161
Length: 237 (215)
Sequences: 1827
Seq/Len: 8.50

YGGC
Paralog alert: 0.64 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: URK YGGC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
129_D 136_V 4.633 1.00
84_F 114_N 2.895 1.00
195_T 198_V 2.892 1.00
87_Y 90_W 2.522 1.00
47_F 168_C 2.424 1.00
90_W 93_A 2.291 1.00
182_R 204_A 2.29 1.00
110_K 114_N 2.271 1.00
107_D 135_P 2.259 1.00
113_E 117_Q 2.259 1.00
124_T 141_H 2.112 1.00
111_L 149_V 2.019 1.00
49_C 155_L 1.895 1.00
157_D 163_E 1.874 1.00
129_D 132_K 1.854 1.00
116_R 163_E 1.83 1.00
116_R 167_F 1.815 1.00
196_R 200_E 1.809 1.00
119_V 169_D 1.73 1.00
178_A 212_E 1.711 1.00
165_A 220_Q 1.708 1.00
46_V 146_L 1.69 1.00
149_V 168_C 1.635 1.00
90_W 94_H 1.613 1.00
92_D 97_R 1.554 1.00
19_E 23_N 1.522 1.00
175_H 218_S 1.501 1.00
159_E 162_L 1.5 1.00
183_E 187_S 1.499 1.00
88_N 100_K 1.469 0.99
81_M 154_L 1.454 0.99
164_L 168_C 1.452 0.99
67_A 78_T 1.452 0.99
122_D 143_T 1.444 0.99
65_Y 68_Q 1.439 0.99
118_V 147_V 1.417 0.99
96_L 104_E 1.408 0.99
124_T 140_L 1.394 0.99
36_Q 159_E 1.386 0.99
122_D 141_H 1.376 0.99
114_N 117_Q 1.371 0.99
128_Y 133_H 1.367 0.99
22_E 26_K 1.354 0.99
89_S 134_D 1.354 0.99
19_E 22_E 1.344 0.99
155_L 171_S 1.344 0.99
36_Q 160_K 1.313 0.99
178_A 208_G 1.312 0.99
50_A 54_T 1.3 0.98
78_T 148_I 1.264 0.98
87_Y 134_D 1.255 0.98
99_F 128_Y 1.249 0.98
26_K 30_H 1.228 0.98
208_G 212_E 1.225 0.98
75_A 145_P 1.223 0.98
83_G 152_N 1.21 0.97
197_Q 201_A 1.191 0.97
127_Q 139_A 1.187 0.97
166_S 220_Q 1.187 0.97
29_L 32_L 1.183 0.97
67_A 148_I 1.178 0.97
182_R 186_I 1.171 0.97
194_L 202_F 1.17 0.97
207_D 210_N 1.167 0.96
130_R 192_G 1.164 0.96
109_A 113_E 1.159 0.96
81_M 108_V 1.158 0.96
124_T 139_A 1.157 0.96
45_V 119_V 1.152 0.96
132_K 136_V 1.15 0.96
48_L 59_L 1.138 0.96
39_N 179_Q 1.137 0.96
117_Q 120_E 1.122 0.95
127_Q 138_D 1.111 0.95
175_H 226_E 1.11 0.95
152_N 155_L 1.098 0.95
84_F 111_L 1.094 0.94
218_S 221_A 1.084 0.94
88_N 133_H 1.08 0.94
85_H 185_L 1.076 0.94
43_R 128_Y 1.072 0.94
50_A 56_K 1.071 0.94
80_P 83_G 1.065 0.93
29_L 70_D 1.064 0.93
187_S 191_A 1.058 0.93
96_L 100_K 1.056 0.93
59_L 174_I 1.054 0.93
130_R 185_L 1.049 0.93
88_N 97_R 1.045 0.92
207_D 211_V 1.044 0.92
18_N 22_E 1.043 0.92
92_D 205_R 1.042 0.92
155_L 221_A 1.041 0.92
17_Q 20_E 1.025 0.91
23_N 26_K 1.022 0.91
178_A 181_L 1.021 0.91
112_T 164_L 1.017 0.91
36_Q 162_L 1.015 0.91
81_M 106_F 1.013 0.91
50_A 55_G 1.011 0.91
124_T 138_D 1.01 0.91
130_R 133_H 1.009 0.91
180_I 183_E 1.004 0.90
36_Q 192_G 1.004 0.90
190_I 199_A 1.003 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2ga8A10.9031000.441Contact Map0.577
3tqcA20.98731000.474Contact Map0.725
4bfzA20.98311000.534Contact Map0.692
2jeoA10.890399.90.574Contact Map0.689
1a7jA10.814399.90.576Contact Map0.489
1odfA10.932599.90.58Contact Map0.497
1rz3A10.814399.90.582Contact Map0.63
4gi7A80.987399.90.586Contact Map0.728
3c8uA10.860899.90.616Contact Map0.633
1uj2A20.877699.90.634Contact Map0.744

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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