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NARI - Respiratory nitrate reductase 1 gamma chain
UniProt: P11350 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10640
Length: 225 (224)
Sequences: 489
Seq/Len: 2.18
NARI
Paralog alert: 0.45 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: NARI NARV
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
51_A 107_L 3.614 1.00
19_V 196_L 2.876 1.00
98_G 141_L 2.589 1.00
172_G 175_Q 2.406 1.00
82_P 85_V 2.27 1.00
18_A 22_I 2.118 1.00
20_F 24_S 2.113 0.99
113_L 119_R 2.003 0.99
7_F 15_I 1.977 0.99
119_R 127_I 1.963 0.99
12_Y 193_T 1.756 0.97
136_Q 191_G 1.73 0.97
62_I 98_G 1.67 0.96
159_L 180_V 1.64 0.96
19_V 200_F 1.637 0.96
24_S 207_W 1.535 0.93
58_G 104_G 1.52 0.93
128_L 197_L 1.518 0.93
20_F 207_W 1.501 0.92
124_G 128_L 1.469 0.91
113_L 127_I 1.452 0.91
106_V 134_V 1.45 0.90
43_L 117_R 1.428 0.90
85_V 89_M 1.42 0.89
38_A 123_T 1.419 0.89
91_M 148_A 1.408 0.89
64_V 67_F 1.407 0.89
59_I 101_C 1.406 0.89
113_L 116_P 1.394 0.88
11_I 169_F 1.39 0.88
33_Y 218_Y 1.384 0.88
189_V 193_T 1.376 0.87
61_G 93_A 1.372 0.87
201_S 209_V 1.366 0.87
182_F 186_L 1.363 0.86
44_D 115_S 1.361 0.86
109_L 127_I 1.348 0.86
78_E 83_I 1.334 0.85
136_Q 190_L 1.329 0.85
32_Q 35_W 1.325 0.84
31_G 218_Y 1.309 0.83
20_F 206_I 1.304 0.83
19_V 22_I 1.289 0.82
8_F 189_V 1.284 0.82
20_F 198_F 1.281 0.81
86_K 163_A 1.274 0.81
106_V 114_F 1.272 0.81
18_A 63_F 1.266 0.80
105_G 109_L 1.26 0.80
169_F 211_V 1.253 0.79
37_A 45_R 1.25 0.79
22_I 25_W 1.242 0.79
86_K 156_M 1.237 0.78
7_F 169_F 1.236 0.78
11_I 15_I 1.236 0.78
110_K 114_F 1.234 0.78
7_F 142_L 1.206 0.76
4_L 63_F 1.198 0.75
64_V 186_L 1.198 0.75
15_I 123_T 1.196 0.75
188_L 192_M 1.184 0.74
217_K 223_A 1.183 0.74
46_K 210_P 1.18 0.73
21_L 214_L 1.177 0.73
125_A 201_S 1.177 0.73
155_E 160_V 1.169 0.72
43_L 129_I 1.151 0.71
44_D 48_M 1.149 0.71
124_G 131_S 1.149 0.71
166_V 192_M 1.144 0.70
99_V 103_I 1.143 0.70
64_V 68_F 1.141 0.70
81_L 85_V 1.14 0.70
102_L 134_V 1.138 0.70
17_G 166_V 1.132 0.69
74_H 157_M 1.132 0.69
84_E 88_K 1.125 0.68
35_W 222_R 1.119 0.68
132_L 173_A 1.119 0.68
48_M 51_A 1.11 0.67
38_A 217_K 1.107 0.66
54_L 103_I 1.104 0.66
194_L 203_L 1.104 0.66
83_I 160_V 1.101 0.66
52_S 118_V 1.098 0.66
163_A 167_V 1.09 0.65
2_Q 48_M 1.081 0.64
47_G 51_A 1.08 0.64
24_S 204_I 1.073 0.63
16_A 67_F 1.073 0.63
49_N 194_L 1.073 0.63
12_Y 196_L 1.066 0.62
11_I 22_I 1.063 0.62
46_K 60_L 1.062 0.62
96_A 220_L 1.06 0.62
125_A 197_L 1.058 0.61
20_F 136_Q 1.053 0.61
158_K 161_G 1.051 0.61
61_G 97_S 1.049 0.60
65_G 69_G 1.048 0.60
155_E 158_K 1.035 0.59
16_A 192_M 1.033 0.59
113_L 123_T 1.029 0.58
134_V 216_R 1.027 0.58
91_M 206_I 1.025 0.58
185_R 188_L 1.023 0.57
139_L 186_L 1.022 0.57
119_R 122_T 1.014 0.56
87_Q 156_M 1.011 0.56
50_L 103_I 1.004 0.55
34_T 220_L 1.003 0.55
220_L 224_R 1.003 0.55
132_L 136_Q 1.002 0.55
67_F 71_L 1.002 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1q16C111000.328Contact Map0.539
2l2tA20.195621.50.961Contact Map0.013
2ks1B10.19569.40.966Contact Map0.056
1pfiA20.20445.60.97Contact Map0.614
2kluA10.29334.10.972Contact Map0.414
2l9uA20.17333.10.973Contact Map0.348
3wajA10.47562.60.974Contact Map0.142
2jwaA20.19562.40.975Contact Map0.486
1iijA10.155620.976Contact Map0.938
2jo1A10.23111.90.976Contact Map0.325
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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