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OPENSEQ.org
NARV - Respiratory nitrate reductase 2 gamma chain
UniProt: P0AF32 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10644
Length: 226 (223)
Sequences: 488
Seq/Len: 2.19
NARV
Paralog alert: 0.45 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: NARI NARV
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_W 108_G 3.609 1.00
20_V 197_L 2.902 1.00
99_G 142_L 2.635 1.00
173_G 176_E 2.229 1.00
83_P 86_A 2.191 1.00
21_F 25_S 2.078 0.99
8_F 16_I 1.956 0.99
114_L 120_R 1.953 0.99
19_T 23_L 1.895 0.99
120_R 128_I 1.874 0.99
63_I 99_G 1.733 0.97
137_Q 192_G 1.699 0.97
160_L 181_V 1.692 0.97
13_Y 194_T 1.622 0.95
25_S 208_W 1.554 0.94
59_G 105_G 1.53 0.93
21_F 208_W 1.513 0.93
20_V 201_F 1.51 0.93
39_S 124_T 1.503 0.92
107_A 135_L 1.5 0.92
114_L 128_I 1.498 0.92
129_I 198_L 1.478 0.92
65_F 68_L 1.466 0.91
12_I 170_F 1.459 0.91
60_I 102_T 1.407 0.89
190_V 194_T 1.407 0.89
86_A 90_M 1.407 0.89
125_T 129_I 1.396 0.88
183_F 187_L 1.396 0.88
44_L 118_R 1.392 0.88
202_T 210_A 1.367 0.87
34_Y 219_Y 1.364 0.87
45_D 116_N 1.362 0.87
20_V 23_L 1.358 0.86
79_A 84_V 1.331 0.85
22_F 215_F 1.32 0.84
114_L 117_Q 1.318 0.84
110_L 128_I 1.316 0.84
106_G 110_L 1.311 0.84
62_G 94_L 1.309 0.83
12_I 16_I 1.3 0.83
9_F 190_V 1.298 0.83
19_T 64_F 1.296 0.83
32_G 219_Y 1.288 0.82
21_F 199_F 1.286 0.82
92_M 149_A 1.283 0.82
23_L 26_W 1.281 0.82
33_Q 36_W 1.276 0.81
137_Q 191_L 1.276 0.81
16_I 124_T 1.273 0.81
87_K 164_A 1.267 0.81
107_A 115_T 1.263 0.80
38_A 46_K 1.257 0.80
87_K 157_M 1.236 0.78
8_F 170_F 1.225 0.77
21_F 207_V 1.214 0.77
5_L 64_F 1.207 0.76
103_L 135_L 1.193 0.75
126_P 202_T 1.192 0.75
18_A 167_I 1.191 0.75
44_L 130_I 1.185 0.74
189_L 193_M 1.185 0.74
65_F 69_F 1.183 0.74
47_R 211_P 1.179 0.74
111_W 115_T 1.177 0.73
218_R 224_S 1.174 0.73
170_F 212_F 1.171 0.73
156_E 161_V 1.171 0.73
101_L 149_A 1.165 0.72
49_M 52_W 1.161 0.72
3_Q 49_M 1.155 0.71
8_F 143_S 1.154 0.71
97_I 221_I 1.152 0.71
167_I 193_M 1.13 0.69
55_L 104_I 1.126 0.69
164_A 168_V 1.126 0.69
75_H 158_M 1.123 0.68
36_W 223_R 1.119 0.68
85_A 89_L 1.117 0.68
143_S 147_F 1.112 0.67
45_D 49_M 1.107 0.67
84_V 161_V 1.107 0.67
39_S 218_R 1.106 0.67
133_I 174_S 1.102 0.66
53_S 119_V 1.097 0.66
195_I 204_L 1.094 0.65
25_S 205_V 1.089 0.65
145_I 164_A 1.086 0.64
140_L 187_L 1.086 0.64
48_G 52_W 1.082 0.64
62_G 98_C 1.082 0.64
50_V 195_I 1.071 0.63
65_F 187_L 1.069 0.63
82_L 86_A 1.067 0.62
13_Y 197_L 1.058 0.61
159_K 162_G 1.057 0.61
89_L 152_P 1.056 0.61
125_T 132_S 1.056 0.61
103_L 139_L 1.056 0.61
45_D 187_L 1.053 0.61
156_E 159_K 1.046 0.60
66_G 70_G 1.037 0.59
126_P 198_L 1.035 0.59
21_F 137_Q 1.032 0.59
120_R 123_S 1.032 0.59
186_R 189_L 1.03 0.58
43_M 52_W 1.029 0.58
12_I 23_L 1.028 0.58
63_I 101_L 1.02 0.57
17_C 68_L 1.017 0.57
20_V 180_G 1.015 0.57
143_S 184_V 1.013 0.56
92_M 207_V 1.012 0.56
88_Q 157_M 1.012 0.56
135_L 217_R 1.011 0.56
114_L 124_T 1.007 0.56
91_A 96_G 1.001 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1q16C10.99561000.334Contact Map0.529
2l2tA20.194724.50.96Contact Map0.015
2ks1B10.19479.60.967Contact Map0.036
1pfiA20.203570.969Contact Map0.732
2kluA10.2925.30.97Contact Map0.01
2l9uA20.17263.40.973Contact Map0.16
2jwaA20.19473.20.973Contact Map0.333
3wajA10.47352.50.975Contact Map0.22
1iijA10.14161.90.976Contact Map0.538
3cx5C20.39821.80.977Contact Map0.58
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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