| UniProt: | P0C0S1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11160 | ||
| Length: | 286 (262) | ||
| Sequences: | 4325 | ||
| Seq/Len: | 16.51 |
| MSCS
Paralog alert: 0.61 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: MSCS YBDG YNAI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 199_D | 259_R | 3.615 | 1.00 | |
| 41_G | 81_T | 3.295 | 1.00 | |
| 137_D | 142_A | 3.213 | 1.00 | |
| 258_K | 262_D | 3.149 | 1.00 | |
| 146_L | 156_R | 3.007 | 1.00 | |
| 227_E | 234_N | 2.938 | 1.00 | |
| 202_K | 255_E | 2.777 | 1.00 | |
| 203_Q | 207_N | 2.725 | 1.00 | |
| 260_E | 263_A | 2.678 | 1.00 | |
| 272_Q | 276_N | 2.662 | 1.00 | |
| 260_E | 264_A | 2.626 | 1.00 | |
| 206_T | 210_Q | 2.537 | 1.00 | |
| 200_Q | 264_A | 2.526 | 1.00 | |
| 212_E | 252_D | 2.5 | 1.00 | |
| 197_D | 200_Q | 2.472 | 1.00 | |
| 135_Y | 142_A | 2.417 | 1.00 | |
| 229_G | 234_N | 2.376 | 1.00 | |
| 225_L | 233_I | 2.325 | 1.00 | |
| 191_G | 232_S | 2.248 | 1.00 | |
| 207_N | 211_S | 2.172 | 1.00 | |
| 200_Q | 203_Q | 2.164 | 1.00 | |
| 207_N | 260_E | 2.114 | 1.00 | |
| 226_N | 236_V | 2.054 | 1.00 | |
| 169_K | 173_G | 2.001 | 1.00 | |
| 192_V | 201_V | 1.979 | 1.00 | |
| 135_Y | 144_T | 1.967 | 1.00 | |
| 216_L | 219_R | 1.91 | 1.00 | |
| 209_I | 237_V | 1.893 | 1.00 | |
| 204_I | 260_E | 1.892 | 1.00 | |
| 201_V | 235_F | 1.799 | 1.00 | |
| 208_I | 260_E | 1.784 | 1.00 | |
| 147_S | 154_T | 1.751 | 1.00 | |
| 157_T | 163_I | 1.741 | 1.00 | |
| 205_L | 257_I | 1.734 | 1.00 | |
| 190_I | 257_I | 1.732 | 1.00 | |
| 239_V | 253_V | 1.709 | 1.00 | |
| 136_V | 145_V | 1.706 | 1.00 | |
| 189_I | 236_V | 1.686 | 1.00 | |
| 137_D | 140_G | 1.636 | 1.00 | |
| 211_S | 256_R | 1.626 | 1.00 | |
| 193_A | 267_S | 1.622 | 1.00 | |
| 99_V | 102_A | 1.604 | 1.00 | |
| 112_Q | 116_S | 1.595 | 1.00 | |
| 195_D | 270_Y | 1.574 | 1.00 | |
| 202_K | 206_T | 1.573 | 1.00 | |
| 77_I | 81_T | 1.564 | 1.00 | |
| 256_R | 259_R | 1.559 | 1.00 | |
| 137_D | 178_F | 1.556 | 1.00 | |
| 191_G | 234_N | 1.516 | 1.00 | |
| 135_Y | 158_A | 1.497 | 1.00 | |
| 230_A | 273_M | 1.483 | 1.00 | |
| 163_I | 176_I | 1.469 | 1.00 | |
| 259_R | 263_A | 1.468 | 1.00 | |
| 204_I | 264_A | 1.463 | 1.00 | |
| 252_D | 256_R | 1.449 | 1.00 | |
| 230_A | 234_N | 1.429 | 1.00 | |
| 196_S | 267_S | 1.426 | 1.00 | |
| 110_A | 115_L | 1.425 | 1.00 | |
| 274_D | 278_K | 1.413 | 1.00 | |
| 274_D | 277_F | 1.399 | 0.99 | |
| 146_L | 162_I | 1.396 | 0.99 | |
| 127_F | 151_F | 1.393 | 0.99 | |
| 199_D | 255_E | 1.393 | 0.99 | |
| 153_T | 167_N | 1.375 | 0.99 | |
| 189_I | 234_N | 1.37 | 0.99 | |
| 105_L | 108_G | 1.369 | 0.99 | |
| 34_A | 85_A | 1.338 | 0.99 | |
| 192_V | 198_I | 1.33 | 0.99 | |
| 191_G | 231_S | 1.32 | 0.99 | |
| 250_Y | 254_L | 1.315 | 0.99 | |
| 191_G | 229_G | 1.301 | 0.99 | |
| 204_I | 207_N | 1.299 | 0.99 | |
| 196_S | 201_V | 1.296 | 0.99 | |
| 113_G | 116_S | 1.294 | 0.99 | |
| 192_V | 196_S | 1.282 | 0.99 | |
| 261_F | 266_I | 1.27 | 0.99 | |
| 193_A | 269_P | 1.266 | 0.99 | |
| 208_I | 256_R | 1.259 | 0.99 | |
| 212_E | 256_R | 1.251 | 0.99 | |
| 86_L | 91_V | 1.251 | 0.99 | |
| 141_V | 174_N | 1.249 | 0.99 | |
| 207_N | 210_Q | 1.242 | 0.98 | |
| 194_Y | 268_F | 1.234 | 0.98 | |
| 228_L | 233_I | 1.226 | 0.98 | |
| 200_Q | 204_I | 1.218 | 0.98 | |
| 85_A | 89_V | 1.217 | 0.98 | |
| 34_A | 89_V | 1.21 | 0.98 | |
| 241_S | 249_V | 1.198 | 0.98 | |
| 212_E | 253_V | 1.17 | 0.97 | |
| 194_Y | 228_L | 1.168 | 0.97 | |
| 139_G | 174_N | 1.163 | 0.97 | |
| 43_I | 47_M | 1.163 | 0.97 | |
| 187_E | 238_R | 1.158 | 0.97 | |
| 149_Q | 154_T | 1.158 | 0.97 | |
| 199_D | 203_Q | 1.157 | 0.97 | |
| 53_N | 70_S | 1.157 | 0.97 | |
| 49_S | 74_R | 1.156 | 0.97 | |
| 137_D | 176_I | 1.151 | 0.97 | |
| 248_N | 252_D | 1.147 | 0.97 | |
| 154_T | 162_I | 1.145 | 0.97 | |
| 205_L | 261_F | 1.139 | 0.97 | |
| 204_I | 261_F | 1.138 | 0.97 | |
| 116_S | 168_G | 1.135 | 0.97 | |
| 198_I | 258_K | 1.127 | 0.97 | |
| 134_E | 180_R | 1.12 | 0.96 | |
| 136_V | 170_I | 1.117 | 0.96 | |
| 191_G | 270_Y | 1.117 | 0.96 | |
| 203_Q | 206_T | 1.114 | 0.96 | |
| 130_F | 153_T | 1.108 | 0.96 | |
| 103_A | 107_V | 1.095 | 0.96 | |
| 211_S | 260_E | 1.082 | 0.96 | |
| 191_G | 194_Y | 1.081 | 0.95 | |
| 194_Y | 231_S | 1.072 | 0.95 | |
| 215_I | 249_V | 1.066 | 0.95 | |
| 138_L | 170_I | 1.057 | 0.95 | |
| 223_V | 237_V | 1.055 | 0.95 | |
| 194_Y | 270_Y | 1.052 | 0.95 | |
| 228_L | 254_L | 1.047 | 0.94 | |
| 187_E | 236_V | 1.046 | 0.94 | |
| 99_V | 104_G | 1.04 | 0.94 | |
| 253_V | 257_I | 1.037 | 0.94 | |
| 214_R | 252_D | 1.024 | 0.93 | |
| 201_V | 205_L | 1.019 | 0.93 | |
| 255_E | 259_R | 1.017 | 0.93 | |
| 45_A | 81_T | 1.01 | 0.93 | |
| 256_R | 260_E | 1.007 | 0.93 | |
| 74_R | 78_I | 1.006 | 0.93 | |
| 102_A | 111_L | 1.005 | 0.93 | |
| 161_K | 176_I | 1.004 | 0.93 | |
| 205_L | 237_V | 1.003 | 0.93 | |
| 192_V | 235_F | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2vv5A | 7 | 1 | 100 | 0.117 | Contact Map | 0.772 |
| 4hw9A | 7 | 0.993 | 100 | 0.149 | Contact Map | 0.703 |
| 3udcA | 7 | 0.951 | 100 | 0.218 | Contact Map | 0.757 |
| 1nz9A | 1 | 0.1678 | 50.1 | 0.947 | Contact Map | 0.512 |
| 2e6zA | 1 | 0.1783 | 38 | 0.951 | Contact Map | 0.724 |
| 2lt1A | 1 | 0.2203 | 23 | 0.956 | Contact Map | 0.446 |
| 3mlqE | 4 | 0.2168 | 17.9 | 0.958 | Contact Map | 0.681 |
| 4l5gA | 2 | 0.4685 | 16.2 | 0.959 | Contact Map | 0.423 |
| 2lt4A | 1 | 0.2098 | 7.9 | 0.964 | Contact Map | 0.28 |
| 3tzuA | 4 | 0.4406 | 6.1 | 0.966 | Contact Map | 0.062 |
Sequence Conservation (Image Generated using WebLogo v3)