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OPENSEQ.org

IBPA - Small heat shock protein IbpA
UniProt: P0C054 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11534
Length: 137 (136)
Sequences: 2245
Seq/Len: 16.51

IBPA
Paralog alert: 0.54 [within 20: 0.19] - ratio of genomes with paralogs
Cluster includes: IBPA IBPB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
51_I 72_V 3.217 1.00
62_E 133_R 2.857 1.00
109_G 137_N 2.679 1.00
46_H 120_D 2.638 1.00
62_E 73_K 2.625 1.00
43_D 46_H 2.417 1.00
37_Y 99_F 2.396 1.00
52_A 90_I 2.276 1.00
127_E 130_K 2.226 1.00
74_G 95_F 2.078 1.00
52_A 116_L 2.077 1.00
53_V 61_L 2.023 1.00
57_A 114_N 1.988 1.00
48_R 118_Y 1.898 1.00
73_K 96_E 1.866 1.00
53_V 112_L 1.84 1.00
57_A 60_E 1.814 1.00
89_G 97_R 1.78 1.00
42_V 123_R 1.774 1.00
50_A 118_Y 1.768 1.00
61_L 112_L 1.748 1.00
65_A 101_L 1.745 1.00
75_A 94_N 1.73 1.00
37_Y 51_I 1.683 1.00
35_P 95_F 1.641 1.00
105_I 121_L 1.639 1.00
43_D 48_R 1.632 1.00
106_H 124_V 1.587 1.00
38_N 90_I 1.58 1.00
71_V 98_K 1.56 1.00
38_N 88_Q 1.44 1.00
111_N 137_N 1.428 1.00
58_E 114_N 1.396 0.99
38_N 52_A 1.343 0.99
69_L 100_Q 1.319 0.99
70_L 119_I 1.306 0.99
74_G 93_R 1.287 0.99
39_V 49_I 1.272 0.99
47_Y 86_L 1.252 0.99
73_K 94_N 1.22 0.98
41_L 48_R 1.166 0.97
20_F 23_L 1.154 0.97
47_Y 103_E 1.153 0.97
53_V 74_G 1.151 0.97
18_R 24_E 1.147 0.97
33_G 74_G 1.142 0.97
60_E 77_A 1.128 0.97
85_Y 88_Q 1.114 0.96
34_Y 38_N 1.107 0.96
56_F 74_G 1.101 0.96
37_Y 72_V 1.097 0.96
64_T 133_R 1.092 0.96
19_L 24_E 1.073 0.95
38_N 53_V 1.063 0.95
69_L 98_K 1.053 0.95
58_E 98_K 1.05 0.94
102_A 105_I 1.031 0.94
49_I 99_F 1.03 0.94
20_F 26_N 1.019 0.93
24_E 28_S 1.013 0.93
61_L 90_I 1.012 0.93
18_R 22_H 1.011 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4eldA20.94161000.2Contact Map0.707
3w1zA40.94161000.228Contact Map0.749
1gmeA40.96351000.241Contact Map0.726
3aabA20.868699.90.298Contact Map0.73
4feiA10.722699.90.331Contact Map0.606
3glaA20.700799.90.333Contact Map0.759
2bolA20.92799.90.354Contact Map0.479
2klrA20.948999.90.364Contact Map0.477
3l1eA10.722699.90.383Contact Map0.637
2wj5A10.686199.90.405Contact Map0.518

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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