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OPENSEQ.org

SODF - Superoxide dismutase [Fe]
UniProt: P0AGD3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10954
Length: 193 (193)
Sequences: 2291
Seq/Len: 11.87

SODF
Paralog alert: 0.40 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: SODF SODM
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
33_Q 37_T 4.503 1.00
170_A 173_G 2.946 1.00
106_D 109_A 2.908 1.00
93_V 188_A 2.653 1.00
186_F 189_K 2.648 1.00
38_N 41_N 2.453 1.00
129_N 135_A 2.426 1.00
94_A 98_A 2.392 1.00
21_A 25_E 2.296 1.00
156_V 175_L 2.274 1.00
186_F 190_N 2.274 1.00
95_E 98_A 2.266 1.00
22_E 168_R 2.214 1.00
115_A 124_T 2.168 1.00
52_S 55_E 2.087 1.00
109_A 113_D 2.07 1.00
19_I 77_Y 2.009 1.00
18_H 180_A 1.996 1.00
96_A 191_L 1.982 1.00
106_D 110_Q 1.977 1.00
173_G 176_E 1.961 1.00
115_A 156_V 1.922 1.00
20_S 166_D 1.889 1.00
41_N 44_K 1.874 1.00
37_T 41_N 1.86 1.00
36_V 71_V 1.844 1.00
12_K 29_G 1.844 1.00
81_L 178_F 1.82 1.00
113_D 117_K 1.793 1.00
100_S 133_K 1.77 1.00
154_L 187_V 1.768 1.00
79_N 186_F 1.765 1.00
118_N 138_S 1.744 1.00
82_A 85_A 1.688 1.00
96_A 99_A 1.682 1.00
127_V 137_V 1.665 1.00
116_I 175_L 1.642 1.00
188_A 192_A 1.604 1.00
112_T 176_E 1.599 1.00
115_A 175_L 1.539 1.00
112_T 116_I 1.516 1.00
13_D 21_A 1.508 1.00
4_E 7_A 1.493 1.00
185_E 188_A 1.493 1.00
88_E 105_A 1.49 1.00
107_F 111_F 1.489 1.00
110_Q 113_D 1.486 1.00
71_V 75_T 1.482 1.00
165_I 168_R 1.473 1.00
80_C 187_V 1.424 1.00
92_K 192_A 1.421 1.00
45_G 49_E 1.421 1.00
32_H 78_W 1.401 0.99
6_P 75_T 1.399 0.99
111_F 156_V 1.391 0.99
39_L 68_A 1.391 0.99
156_V 178_F 1.38 0.99
105_A 108_K 1.373 0.99
11_A 14_A 1.327 0.99
129_N 150_A 1.31 0.99
112_T 175_L 1.301 0.99
5_L 28_Y 1.296 0.99
125_W 139_T 1.278 0.99
24_I 77_Y 1.275 0.99
22_E 25_E 1.264 0.99
25_E 29_G 1.257 0.99
116_I 172_P 1.244 0.98
104_F 107_F 1.238 0.98
118_N 124_T 1.23 0.98
95_E 99_A 1.22 0.98
127_V 135_A 1.204 0.98
96_A 100_S 1.203 0.98
92_K 95_E 1.203 0.98
38_N 67_N 1.183 0.98
179_W 182_V 1.177 0.98
167_Y 177_H 1.167 0.97
51_K 59_S 1.165 0.97
158_V 171_R 1.163 0.97
3_F 39_L 1.163 0.97
43_I 46_T 1.159 0.97
39_L 64_V 1.152 0.97
128_K 191_L 1.143 0.97
90_T 188_A 1.131 0.97
153_L 187_V 1.131 0.97
79_N 190_N 1.125 0.97
72_W 144_T 1.121 0.97
92_K 188_A 1.115 0.96
178_F 182_V 1.112 0.96
9_P 79_N 1.108 0.96
163_Y 171_R 1.105 0.96
12_K 25_E 1.101 0.96
69_A 142_A 1.09 0.96
182_V 187_V 1.085 0.96
135_A 150_A 1.084 0.96
3_F 43_I 1.083 0.96
30_K 170_A 1.081 0.95
114_A 136_I 1.077 0.95
109_A 176_E 1.073 0.95
111_F 178_F 1.072 0.95
124_T 138_S 1.065 0.95
107_F 136_I 1.062 0.95
101_F 110_Q 1.056 0.95
114_A 124_T 1.054 0.95
12_K 28_Y 1.043 0.94
82_A 86_G 1.031 0.94
76_F 186_F 1.03 0.94
65_F 143_G 1.027 0.94
112_T 179_W 1.022 0.93
108_K 180_A 1.021 0.93
44_K 49_E 1.017 0.93
93_V 187_V 1.012 0.93
34_T 38_N 1.008 0.93
51_K 55_E 1.005 0.93
88_E 94_A 1.003 0.93
154_L 182_V 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tqjA21100-0.038Contact Map0.804
1gv3A21100-0.038Contact Map0.787
1mngA21100-0.038Contact Map0.78
4k2wA21100-0.037Contact Map0.769
1uerA40.9896100-0.037Contact Map0.83
2awpA21100-0.036Contact Map0.775
2cw2A20.9948100-0.035Contact Map0.781
2rcvA80.9948100-0.034Contact Map0.804
2nybA40.9948100-0.033Contact Map0.805
1dt0A30.9948100-0.031Contact Map0.816

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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