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OPENSEQ.org
RSSA - NTE family protein RssA
UniProt: P0AFR0 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12120
Length: 301 (286)
Sequences: 2201
Seq/Len: 7.70
RSSA
Paralog alert: 0.61 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: RSSA YJJU
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
115_N 151_Y 4.363 1.00
26_A 283_Q 3.834 1.00
48_A 133_I 3.364 1.00
29_K 283_Q 3.14 1.00
115_N 122_L 2.836 1.00
23_V 178_V 2.749 1.00
25_N 283_Q 2.657 1.00
162_I 177_A 2.635 1.00
280_A 284_L 2.596 1.00
25_N 59_E 2.565 1.00
121_E 160_N 2.541 1.00
26_A 29_K 2.498 1.00
274_R 277_A 2.466 1.00
47_G 109_F 2.462 1.00
113_A 124_F 2.461 1.00
276_H 280_A 2.431 1.00
148_H 153_L 2.352 1.00
26_A 286_V 2.33 1.00
26_A 287_E 2.328 1.00
267_I 278_A 2.168 1.00
44_S 136_S 2.15 1.00
122_L 153_L 2.13 1.00
7_G 167_T 2.12 1.00
63_T 276_H 2.11 1.00
38_A 167_T 2.085 1.00
289_K 292_E 2.05 1.00
8_L 24_I 2.01 1.00
7_G 36_I 2.005 1.00
147_A 150_G 1.959 1.00
25_N 56_S 1.936 1.00
260_I 285_A 1.909 1.00
284_L 288_R 1.891 1.00
44_S 137_C 1.813 1.00
105_C 129_L 1.802 1.00
114_T 159_V 1.8 1.00
124_F 153_L 1.799 1.00
12_S 161_P 1.738 1.00
160_N 165_S 1.731 1.00
154_V 158_V 1.705 1.00
30_V 287_E 1.701 1.00
12_S 40_C 1.677 1.00
37_V 47_G 1.665 1.00
28_K 50_Y 1.644 1.00
19_S 285_A 1.642 1.00
112_V 121_E 1.594 1.00
101_E 104_N 1.586 1.00
7_G 172_A 1.584 1.00
177_A 256_P 1.556 1.00
86_G 134_R 1.545 1.00
29_K 55_L 1.544 1.00
26_A 290_M 1.527 1.00
9_A 167_T 1.527 1.00
100_T 104_N 1.505 0.99
90_F 131_L 1.49 0.99
121_E 159_V 1.487 0.99
168_R 175_V 1.481 0.99
147_A 152_W 1.464 0.99
179_D 261_Q 1.451 0.99
128_D 131_L 1.442 0.99
110_A 170_L 1.436 0.99
110_A 166_L 1.435 0.99
283_Q 287_E 1.425 0.99
11_G 162_I 1.409 0.99
271_D 274_R 1.364 0.99
124_F 132_A 1.354 0.99
110_A 123_W 1.35 0.99
131_L 146_V 1.346 0.99
26_A 30_V 1.346 0.99
9_A 38_A 1.341 0.99
30_V 290_M 1.335 0.98
29_K 287_E 1.33 0.98
115_N 118_T 1.329 0.98
22_G 282_G 1.312 0.98
89_V 137_C 1.307 0.98
286_V 290_M 1.291 0.98
52_C 97_M 1.285 0.98
5_K 35_D 1.271 0.98
30_V 294_L 1.268 0.98
59_E 63_T 1.266 0.98
35_D 171_G 1.259 0.98
75_D 86_G 1.247 0.97
36_I 167_T 1.242 0.97
140_P 158_V 1.238 0.97
258_I 293_L 1.232 0.97
17_G 20_H 1.228 0.97
290_M 294_L 1.22 0.97
165_S 169_A 1.211 0.97
102_I 111_A 1.209 0.97
123_W 166_L 1.203 0.97
239_I 242_L 1.194 0.96
47_G 111_A 1.191 0.96
280_A 283_Q 1.182 0.96
14_A 139_I 1.177 0.96
35_D 172_A 1.177 0.96
291_D 297_V 1.176 0.96
248_R 254_D 1.173 0.96
266_Q 281_A 1.161 0.96
30_V 291_D 1.159 0.95
23_V 286_V 1.148 0.95
110_A 125_T 1.148 0.95
285_A 288_R 1.145 0.95
38_A 166_L 1.14 0.95
113_A 122_L 1.135 0.95
7_G 35_D 1.127 0.94
27_L 286_V 1.121 0.94
167_T 172_A 1.12 0.94
113_A 153_L 1.115 0.94
122_L 151_Y 1.113 0.94
15_A 272_F 1.111 0.94
167_T 175_V 1.111 0.94
34_I 176_I 1.11 0.94
213_L 216_R 1.102 0.94
37_V 51_A 1.095 0.93
167_T 171_G 1.088 0.93
178_V 262_P 1.08 0.93
166_L 170_L 1.079 0.93
45_L 93_Y 1.076 0.93
133_I 136_S 1.073 0.92
281_A 284_L 1.069 0.92
116_L 154_V 1.064 0.92
10_L 24_I 1.053 0.91
17_G 42_I 1.052 0.91
37_V 107_R 1.051 0.91
113_A 132_A 1.049 0.91
176_I 297_V 1.046 0.91
120_R 151_Y 1.044 0.91
283_Q 286_V 1.044 0.91
5_K 173_D 1.035 0.90
108_R 125_T 1.031 0.90
24_I 50_Y 1.027 0.90
10_L 47_G 1.015 0.89
281_A 285_A 1.011 0.89
51_A 107_R 1.009 0.89
36_I 172_A 1.006 0.89
284_L 287_E 1.004 0.89
28_K 55_L 1.001 0.88
37_V 48_A 1.001 0.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4akfA10.90371000.299Contact Map0.596
3tu3B10.8871000.397Contact Map0.539
1oxwA30.91361000.459Contact Map0.609
1cjyA20.79499.70.764Contact Map0.24
2itmA20.305635.20.955Contact Map0.138
3k89A10.687729.70.956Contact Map0.375
4ehuA20.229222.90.959Contact Map0.261
3iujA10.59819.40.96Contact Map0.191
2dstA20.272415.70.962Contact Map0.081
2xdwA10.59814.50.962Contact Map0.157
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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