May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

YJCO - Uncharacterized protein YjcO
UniProt: P0AF56 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11951
Length: 229 (207)
Sequences: 3255
Seq/Len: 15.72

YJCO
Paralog alert: 0.78 [within 20: 0.63] - ratio of genomes with paralogs
Cluster includes: YBEQ YBET YJCO
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
190_L 208_L 2.777 1.00
88_Q 91_V 2.598 1.00
153_A 169_F 2.531 1.00
203_K 206_H 2.435 1.00
124_K 127_S 2.429 1.00
46_F 58_A 2.409 1.00
38_Q 64_S 2.397 1.00
53_K 56_Y 2.369 1.00
164_K 167_W 2.308 1.00
105_E 135_D 2.276 1.00
145_Q 168_Y 2.227 1.00
212_C 220_C 2.162 1.00
113_V 129_L 2.105 1.00
105_E 128_L 2.093 1.00
70_C 99_A 2.039 1.00
38_Q 57_W 1.943 1.00
78_I 93_A 1.921 1.00
70_C 92_L 1.862 1.00
130_E 134_E 1.776 1.00
59_Q 63_D 1.772 1.00
145_Q 175_I 1.67 1.00
108_L 112_L 1.656 1.00
71_A 104_G 1.563 1.00
89_A 93_A 1.551 1.00
94_E 98_Q 1.549 1.00
62_A 70_C 1.544 1.00
152_Y 158_I 1.527 1.00
128_L 131_N 1.517 1.00
85_D 88_Q 1.502 1.00
90_K 94_E 1.487 1.00
185_A 189_F 1.48 1.00
149_G 169_F 1.477 1.00
54_A 58_A 1.476 1.00
39_Y 66_D 1.458 1.00
182_E 214_E 1.454 1.00
166_T 170_K 1.451 1.00
148_L 152_Y 1.435 1.00
39_Y 69_A 1.43 1.00
27_L 31_E 1.419 1.00
126_I 130_E 1.416 1.00
126_I 158_I 1.38 0.99
207_W 210_L 1.376 0.99
125_A 129_L 1.372 0.99
205_L 209_N 1.371 0.99
73_L 77_K 1.368 0.99
209_N 213_M 1.363 0.99
55_E 59_Q 1.356 0.99
106_V 137_E 1.343 0.99
170_K 174_A 1.335 0.99
168_Y 171_R 1.332 0.99
88_Q 92_L 1.327 0.99
25_Q 29_A 1.312 0.99
182_E 207_W 1.311 0.99
30_A 38_Q 1.307 0.99
166_T 196_F 1.302 0.99
41_L 45_W 1.293 0.99
26_Y 40_F 1.292 0.99
39_Y 72_L 1.265 0.99
50_D 53_K 1.264 0.99
206_H 210_L 1.258 0.99
55_E 82_V 1.255 0.99
90_K 108_L 1.255 0.99
86_Y 116_Q 1.254 0.99
183_Y 216_F 1.238 0.98
186_G 208_L 1.236 0.98
221_E 224_E 1.233 0.98
122_Y 156_V 1.226 0.98
192_G 195_G 1.224 0.98
42_A 58_A 1.222 0.98
106_V 147_L 1.216 0.98
203_K 207_W 1.213 0.98
109_A 129_L 1.211 0.98
27_L 53_K 1.211 0.98
71_A 107_T 1.211 0.98
92_L 95_K 1.209 0.98
90_K 118_G 1.199 0.98
97_A 105_E 1.194 0.98
55_E 73_L 1.193 0.98
30_A 57_W 1.191 0.98
59_Q 88_Q 1.182 0.98
166_T 185_A 1.18 0.98
183_Y 222_E 1.176 0.98
74_A 93_A 1.173 0.98
146_M 184_W 1.168 0.97
121_D 124_K 1.154 0.97
115_T 118_G 1.15 0.97
200_N 203_K 1.138 0.97
29_A 34_D 1.136 0.97
119_K 159_K 1.132 0.97
130_E 164_K 1.132 0.97
126_I 148_L 1.131 0.97
94_E 124_K 1.124 0.97
133_S 168_Y 1.122 0.97
56_Y 60_K 1.114 0.96
161_D 164_K 1.095 0.96
205_L 223_F 1.086 0.96
106_V 144_A 1.082 0.96
146_M 177_R 1.06 0.95
93_A 107_T 1.057 0.95
110_H 129_L 1.052 0.95
25_Q 28_K 1.051 0.94
132_A 137_E 1.051 0.94
36_R 66_D 1.05 0.94
124_K 128_L 1.037 0.94
61_A 66_D 1.025 0.93
102_K 137_E 1.022 0.93
155_G 158_I 1.021 0.93
204_A 208_L 1.016 0.93
26_Y 29_A 1.01 0.93
53_K 57_W 1.008 0.93
170_K 185_A 1.005 0.93
56_Y 91_V 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2xm6A10.96941000.249Contact Map0.848
1ouvA10.96941000.33Contact Map0.817
3e4bA40.960799.90.519Contact Map0.718
3rjvA10.895299.90.539Contact Map0.663
1klxA10.602699.90.565Contact Map0.687
2q7fA20.908399.20.758Contact Map0.776
3dssA10.95299.20.758Contact Map0.421
1w3bA20.908399.20.759Contact Map0.761
3draA10.921499.20.761Contact Map0.41
2xpiA20.925899.20.761Contact Map0.741

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.082 seconds.