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OPENSEQ.org
FDNI - Formate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunit
UniProt: P0AEK7 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11229
Length: 217 (204)
Sequences: 953
Seq/Len: 4.67
FDNI
Paralog alert: 0.58 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: CYBH FDNI FDOI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
21_V 67_A 2.554 1.00
65_F 132_V 2.381 1.00
61_G 64_I 2.343 1.00
27_L 60_F 2.207 1.00
194_K 201_Y 2.142 1.00
8_V 187_K 2.096 1.00
64_I 124_I 2.045 1.00
20_T 67_A 1.997 1.00
190_R 205_E 1.776 1.00
10_T 109_Y 1.759 1.00
108_K 113_Q 1.743 1.00
22_V 170_M 1.677 0.99
8_V 11_K 1.676 0.99
27_L 56_L 1.651 0.99
24_C 128_L 1.607 0.99
24_C 63_A 1.591 0.99
109_Y 113_Q 1.544 0.99
36_F 156_A 1.534 0.99
130_T 154_I 1.53 0.99
126_V 158_A 1.529 0.99
86_I 90_L 1.492 0.98
62_I 66_V 1.489 0.98
62_I 135_W 1.413 0.97
85_D 114_K 1.391 0.97
11_K 14_D 1.351 0.96
193_A 200_W 1.344 0.96
122_S 126_V 1.334 0.96
85_D 88_W 1.33 0.96
58_P 135_W 1.313 0.95
34_S 53_G 1.309 0.95
58_P 61_G 1.307 0.95
16_A 70_F 1.305 0.95
33_I 159_G 1.285 0.94
127_L 158_A 1.282 0.94
106_V 111_A 1.275 0.94
116_M 119_S 1.274 0.94
52_M 56_L 1.269 0.94
202_R 205_E 1.265 0.94
153_L 157_A 1.258 0.94
134_I 152_L 1.257 0.94
84_K 199_R 1.252 0.93
157_A 170_M 1.249 0.93
26_F 30_L 1.239 0.93
198_P 202_R 1.235 0.93
45_Q 48_G 1.225 0.92
99_N 102_K 1.209 0.92
107_G 203_E 1.206 0.92
150_Y 154_I 1.206 0.92
130_T 133_I 1.205 0.92
190_R 201_Y 1.204 0.91
173_A 180_I 1.203 0.91
21_V 71_M 1.196 0.91
195_K 198_P 1.186 0.91
73_V 86_I 1.18 0.90
181_K 185_E 1.168 0.90
201_Y 204_I 1.166 0.90
78_H 108_K 1.163 0.89
9_R 188_V 1.159 0.89
35_F 126_V 1.15 0.89
5_K 190_R 1.149 0.89
193_A 196_H 1.148 0.89
88_W 114_K 1.144 0.88
178_G 188_V 1.132 0.88
12_F 16_A 1.128 0.87
119_S 123_M 1.127 0.87
203_E 206_K 1.122 0.87
23_I 27_L 1.119 0.87
93_V 99_N 1.119 0.87
83_K 129_V 1.115 0.87
54_R 58_P 1.113 0.87
16_A 130_T 1.11 0.86
26_F 72_F 1.108 0.86
192_W 197_H 1.106 0.86
58_P 175_W 1.105 0.86
25_F 162_L 1.088 0.85
105_D 198_P 1.085 0.85
79_N 109_Y 1.077 0.84
123_M 158_A 1.077 0.84
56_L 60_F 1.054 0.82
74_R 134_I 1.051 0.82
68_L 128_L 1.051 0.82
104_A 161_I 1.05 0.82
144_P 147_V 1.049 0.82
9_R 85_D 1.046 0.82
105_D 199_R 1.031 0.80
133_I 184_I 1.03 0.80
11_K 21_V 1.029 0.80
37_F 61_G 1.024 0.80
21_V 24_C 1.022 0.79
137_P 148_V 1.019 0.79
16_A 20_T 1.011 0.78
202_R 206_K 1.007 0.78
27_L 150_Y 1.006 0.78
156_A 160_I 1.004 0.78
10_T 17_C 1 0.77
69_M 125_F 1 0.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1kqfC111000.296Contact Map0.555
4gd3A20.92171000.537Contact Map0.582
2qjyA60.875680.10.926Contact Map0.422
4h44A10.78876.10.929Contact Map0.508
1pp9C20.917174.80.93Contact Map0.462
3cx5C20.935572.80.931Contact Map0.343
3ixzA10.41016.60.961Contact Map0.009
2czsA20.15674.30.964Contact Map0.423
2zxeA10.41013.90.965Contact Map0.064
2qfaC10.19823.60.965Contact Map0.146
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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