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OPENSEQ.org
RIMO - Ribosomal protein S12 methylthiotransferase RimO
UniProt: P0AEI4 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13478
Length: 441 (430)
Sequences: 3780
Seq/Len: 8.79
RIMO
Paralog alert: 0.80 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: MIAB RIMO
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
268_S 315_D 4.457 1.00
269_P 282_D 4.211 1.00
268_S 318_M 4.061 1.00
144_L 178_A 3.908 1.00
327_R 373_E 3.815 1.00
427_K 439_S 3.566 1.00
324_K 369_Q 3.481 1.00
384_L 425_R 3.479 1.00
245_D 290_Q 3.454 1.00
382_E 425_R 3.366 1.00
321_D 325_E 3.255 1.00
387_I 412_L 3.14 1.00
270_R 315_D 3.109 1.00
358_E 362_R 3.002 1.00
249_P 294_I 2.98 1.00
285_L 325_E 2.965 1.00
270_R 274_L 2.932 1.00
429_E 439_S 2.735 1.00
176_S 179_K 2.733 1.00
260_L 298_L 2.629 1.00
225_Q 228_K 2.624 1.00
178_A 189_I 2.603 1.00
182_V 231_I 2.519 1.00
382_E 427_K 2.475 1.00
320_L 366_L 2.44 1.00
179_K 183_D 2.432 1.00
286_A 289_K 2.422 1.00
178_A 226_L 2.416 1.00
321_D 324_K 2.412 1.00
316_F 362_R 2.387 1.00
285_L 326_A 2.337 1.00
291_W 298_L 2.331 1.00
224_E 253_E 2.327 1.00
14_S 24_S 2.253 1.00
317_Q 321_D 2.25 1.00
324_K 366_L 2.249 1.00
355_V 358_E 2.249 1.00
313_E 317_Q 2.206 1.00
384_L 423_I 2.188 1.00
313_E 355_V 2.135 1.00
153_R 165_D 2.081 1.00
281_V 318_M 2.081 1.00
108_Q 111_E 2.075 1.00
315_D 318_M 2.056 1.00
338_P 350_Q 1.988 1.00
379_V 431_A 1.981 1.00
289_K 325_E 1.955 1.00
218_S 246_D 1.953 1.00
266_H 319_L 1.95 1.00
372_A 376_Q 1.94 1.00
227_S 255_K 1.929 1.00
335_K 360_W 1.903 1.00
327_R 370_I 1.901 1.00
260_L 291_W 1.877 1.00
9_K 37_D 1.876 1.00
317_Q 362_R 1.863 1.00
249_P 253_E 1.853 1.00
352_P 355_V 1.848 1.00
283_R 286_A 1.843 1.00
271_I 274_L 1.83 1.00
218_S 221_S 1.828 1.00
12_F 24_S 1.823 1.00
289_K 293_E 1.821 1.00
353_E 356_K 1.8 1.00
384_L 400_M 1.795 1.00
385_V 397_G 1.791 1.00
252_A 294_I 1.789 1.00
41_S 44_D 1.747 1.00
269_P 281_V 1.721 1.00
171_I 225_Q 1.714 1.00
281_V 285_L 1.702 1.00
378_K 383_I 1.694 1.00
245_D 249_P 1.686 1.00
264_L 322_F 1.68 1.00
314_E 318_M 1.654 1.00
280_S 283_R 1.644 1.00
169_R 177_E 1.642 1.00
387_I 424_L 1.641 1.00
374_R 377_E 1.637 1.00
378_K 381_R 1.622 1.00
313_E 362_R 1.617 1.00
282_D 286_A 1.611 1.00
224_E 246_D 1.607 1.00
318_M 321_D 1.601 1.00
329_D 374_R 1.59 1.00
320_L 362_R 1.583 1.00
182_V 232_W 1.579 1.00
313_E 358_E 1.559 1.00
232_W 237_Y 1.554 1.00
182_V 229_L 1.554 1.00
54_G 162_M 1.554 1.00
281_V 322_F 1.537 1.00
84_G 100_I 1.524 1.00
155_T 308_F 1.522 1.00
248_I 291_W 1.522 1.00
281_V 321_D 1.517 1.00
258_P 400_M 1.511 1.00
258_P 297_E 1.494 1.00
426_V 438_G 1.489 1.00
232_W 236_H 1.488 1.00
357_E 361_N 1.48 1.00
286_A 290_Q 1.48 1.00
88_D 92_E 1.471 1.00
314_E 317_Q 1.466 1.00
155_T 276_K 1.459 1.00
419_K 422_D 1.456 0.99
274_L 308_F 1.431 0.99
223_C 256_I 1.416 0.99
227_S 254_G 1.409 0.99
290_Q 293_E 1.404 0.99
297_E 381_R 1.403 0.99
227_S 250_L 1.403 0.99
236_H 239_Y 1.391 0.99
297_E 377_E 1.368 0.99
239_Y 242_P 1.368 0.99
274_L 315_D 1.361 0.99
333_C 360_W 1.358 0.99
379_V 430_H 1.358 0.99
327_R 374_R 1.356 0.99
34_E 114_H 1.35 0.99
170_P 173_E 1.345 0.99
57_D 61_Q 1.339 0.99
312_T 315_D 1.33 0.99
175_L 179_K 1.327 0.99
304_F 323_L 1.31 0.99
288_I 300_L 1.307 0.99
176_S 180_R 1.298 0.99
366_L 370_I 1.287 0.98
236_H 242_P 1.275 0.98
10_I 38_V 1.274 0.98
335_K 357_E 1.263 0.98
27_I 80_T 1.258 0.98
251_M 256_I 1.254 0.98
49_I 78_I 1.249 0.98
224_E 250_L 1.247 0.98
376_Q 431_A 1.245 0.98
235_L 238_V 1.241 0.98
269_P 318_M 1.238 0.98
353_E 357_E 1.232 0.98
153_R 161_S 1.231 0.98
237_Y 242_P 1.23 0.98
376_Q 379_V 1.23 0.98
158_I 162_M 1.225 0.98
85_A 102_G 1.222 0.98
410_V 428_V 1.221 0.98
338_P 345_N 1.218 0.98
430_H 437_W 1.21 0.97
9_K 44_D 1.205 0.97
366_L 369_Q 1.203 0.97
385_V 426_V 1.203 0.97
428_V 436_L 1.202 0.97
367_Q 370_I 1.195 0.97
327_R 377_E 1.194 0.97
180_R 184_A 1.193 0.97
78_I 99_E 1.19 0.97
295_C 298_L 1.187 0.97
221_S 225_Q 1.173 0.97
175_L 225_Q 1.164 0.97
169_R 173_E 1.16 0.97
306_V 316_F 1.158 0.96
232_W 239_Y 1.154 0.96
323_L 363_F 1.154 0.96
335_K 353_E 1.151 0.96
302_S 331_V 1.151 0.96
365_Q 369_Q 1.143 0.96
276_K 343_D 1.142 0.96
269_P 280_S 1.139 0.96
369_Q 373_E 1.138 0.96
274_L 310_G 1.13 0.96
251_M 260_L 1.124 0.96
52_T 79_V 1.114 0.95
235_L 239_Y 1.107 0.95
80_T 101_T 1.105 0.95
361_N 365_Q 1.104 0.95
333_C 364_M 1.1 0.95
13_V 66_A 1.096 0.95
274_L 347_L 1.095 0.95
317_Q 320_L 1.09 0.95
221_S 246_D 1.09 0.95
180_R 183_D 1.087 0.94
316_F 363_F 1.078 0.94
248_I 294_I 1.077 0.94
142_A 181_L 1.074 0.94
219_M 247_V 1.066 0.94
252_A 295_C 1.065 0.94
220_V 250_L 1.064 0.94
412_L 426_V 1.063 0.94
260_L 300_L 1.057 0.93
71_L 77_V 1.052 0.93
144_L 189_I 1.051 0.93
386_I 423_I 1.05 0.93
368_Q 434_Y 1.049 0.93
345_N 350_Q 1.048 0.93
383_I 428_V 1.04 0.93
250_L 256_I 1.036 0.92
172_G 176_S 1.034 0.92
171_I 199_Y 1.034 0.92
350_Q 356_K 1.033 0.92
367_Q 371_S 1.027 0.92
233_T 237_Y 1.025 0.92
308_F 347_L 1.023 0.92
61_Q 65_E 1.023 0.92
18_P 406_I 1.021 0.92
19_K 194_Q 1.016 0.91
251_M 295_C 1.013 0.91
304_F 331_V 1.008 0.91
232_W 242_P 1.002 0.91
238_V 241_Y 1 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4jc0A20.95691000.325Contact Map0.687
2qgqA80.66441000.534Contact Map0.792
1oltA10.75061000.778Contact Map0.448
2yx0A10.689399.80.845Contact Map0.469
3iixA10.74699.80.847Contact Map0.572
3t7vA10.74699.80.852Contact Map0.476
2z2uA10.623699.80.852Contact Map0.515
1r30A20.759699.80.852Contact Map0.507
3c8fA10.523899.80.853Contact Map0.456
4fhdA10.768799.80.858Contact Map0.365
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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