| UniProt: | P0AE78 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13654 | ||
| Length: | 292 (253) | ||
| Sequences: | 3583 | ||
| Seq/Len: | 14.16 |
| CORC
Paralog alert: 0.73 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: CORC YFJD YTFL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 249_H | 255_E | 4.078 | 1.00 | |
| 79_M | 178_L | 3.8 | 1.00 | |
| 214_V | 279_V | 3.342 | 1.00 | |
| 258_D | 263_Q | 2.929 | 1.00 | |
| 256_T | 265_K | 2.904 | 1.00 | |
| 213_T | 267_A | 2.896 | 1.00 | |
| 81_T | 106_I | 2.714 | 1.00 | |
| 107_S | 112_H | 2.632 | 1.00 | |
| 256_T | 263_Q | 2.539 | 1.00 | |
| 167_I | 178_L | 2.518 | 1.00 | |
| 87_T | 90_E | 2.516 | 1.00 | |
| 105_V | 139_L | 2.49 | 1.00 | |
| 243_V | 277_V | 2.451 | 1.00 | |
| 145_V | 154_M | 2.406 | 1.00 | |
| 208_S | 211_T | 2.343 | 1.00 | |
| 107_S | 136_D | 2.293 | 1.00 | |
| 149_K | 157_E | 2.241 | 1.00 | |
| 121_D | 140_R | 2.223 | 1.00 | |
| 57_M | 61_V | 2.184 | 1.00 | |
| 223_F | 227_F | 2.144 | 1.00 | |
| 86_Q | 90_E | 2.064 | 1.00 | |
| 263_Q | 280_K | 2.055 | 1.00 | |
| 167_I | 175_V | 1.987 | 1.00 | |
| 79_M | 175_V | 1.944 | 1.00 | |
| 111_D | 174_G | 1.923 | 1.00 | |
| 213_T | 276_Q | 1.912 | 1.00 | |
| 134_S | 137_K | 1.889 | 1.00 | |
| 72_I | 151_V | 1.839 | 1.00 | |
| 81_T | 110_K | 1.821 | 1.00 | |
| 82_L | 91_C | 1.816 | 1.00 | |
| 84_R | 107_S | 1.815 | 1.00 | |
| 207_L | 211_T | 1.794 | 1.00 | |
| 265_K | 280_K | 1.792 | 1.00 | |
| 268_M | 275_I | 1.757 | 1.00 | |
| 67_Q | 71_D | 1.757 | 1.00 | |
| 206_Q | 212_W | 1.74 | 1.00 | |
| 101_S | 118_M | 1.725 | 1.00 | |
| 84_R | 136_D | 1.72 | 1.00 | |
| 41_I | 58_L | 1.712 | 1.00 | |
| 85_N | 107_S | 1.711 | 1.00 | |
| 211_T | 278_H | 1.677 | 1.00 | |
| 218_A | 239_I | 1.675 | 1.00 | |
| 57_M | 188_I | 1.668 | 1.00 | |
| 83_K | 86_Q | 1.657 | 1.00 | |
| 265_K | 278_H | 1.65 | 1.00 | |
| 194_D | 197_D | 1.638 | 1.00 | |
| 185_L | 189_V | 1.633 | 1.00 | |
| 218_A | 223_F | 1.625 | 1.00 | |
| 95_I | 103_F | 1.617 | 1.00 | |
| 69_V | 154_M | 1.617 | 1.00 | |
| 86_Q | 91_C | 1.615 | 1.00 | |
| 242_L | 259_I | 1.609 | 1.00 | |
| 93_D | 97_E | 1.577 | 1.00 | |
| 268_M | 276_Q | 1.576 | 1.00 | |
| 182_E | 186_E | 1.563 | 1.00 | |
| 116_I | 142_A | 1.556 | 1.00 | |
| 84_R | 114_E | 1.549 | 1.00 | |
| 224_N | 229_T | 1.534 | 1.00 | |
| 239_I | 277_V | 1.53 | 1.00 | |
| 223_F | 279_V | 1.515 | 1.00 | |
| 207_L | 213_T | 1.497 | 1.00 | |
| 107_S | 114_E | 1.447 | 1.00 | |
| 156_K | 159_R | 1.443 | 1.00 | |
| 213_T | 278_H | 1.437 | 1.00 | |
| 98_S | 103_F | 1.434 | 1.00 | |
| 102_R | 164_H | 1.427 | 1.00 | |
| 204_F | 218_A | 1.419 | 1.00 | |
| 82_L | 105_V | 1.416 | 1.00 | |
| 44_S | 48_D | 1.408 | 1.00 | |
| 267_A | 278_H | 1.388 | 0.99 | |
| 154_M | 179_V | 1.383 | 0.99 | |
| 151_V | 184_I | 1.383 | 0.99 | |
| 270_D | 275_I | 1.381 | 0.99 | |
| 147_E | 176_S | 1.369 | 0.99 | |
| 109_D | 112_H | 1.366 | 0.99 | |
| 244_M | 274_I | 1.355 | 0.99 | |
| 223_F | 239_I | 1.332 | 0.99 | |
| 246_A | 259_I | 1.323 | 0.99 | |
| 264_F | 279_V | 1.298 | 0.99 | |
| 37_L | 44_S | 1.29 | 0.99 | |
| 108_E | 112_H | 1.269 | 0.99 | |
| 113_I | 167_I | 1.262 | 0.99 | |
| 220_I | 236_V | 1.252 | 0.99 | |
| 76_R | 174_G | 1.246 | 0.98 | |
| 64_I | 184_I | 1.232 | 0.98 | |
| 214_V | 223_F | 1.226 | 0.98 | |
| 33_N | 36_E | 1.223 | 0.98 | |
| 264_F | 277_V | 1.19 | 0.98 | |
| 207_L | 210_H | 1.189 | 0.98 | |
| 236_V | 245_Q | 1.183 | 0.98 | |
| 224_N | 231_F | 1.178 | 0.98 | |
| 243_V | 257_I | 1.177 | 0.98 | |
| 61_V | 188_I | 1.164 | 0.97 | |
| 182_E | 192_I | 1.157 | 0.97 | |
| 102_R | 182_E | 1.155 | 0.97 | |
| 220_I | 224_N | 1.148 | 0.97 | |
| 204_F | 214_V | 1.146 | 0.97 | |
| 214_V | 239_I | 1.144 | 0.97 | |
| 206_Q | 209_R | 1.143 | 0.97 | |
| 267_A | 276_Q | 1.14 | 0.97 | |
| 262_Y | 279_V | 1.136 | 0.97 | |
| 204_F | 226_A | 1.131 | 0.97 | |
| 262_Y | 281_I | 1.122 | 0.97 | |
| 116_I | 165_M | 1.106 | 0.96 | |
| 78_Q | 217_L | 1.106 | 0.96 | |
| 72_I | 179_V | 1.105 | 0.96 | |
| 243_V | 266_V | 1.094 | 0.96 | |
| 149_K | 154_M | 1.093 | 0.96 | |
| 205_R | 213_T | 1.089 | 0.96 | |
| 34_R | 66_D | 1.088 | 0.96 | |
| 263_Q | 282_P | 1.087 | 0.96 | |
| 33_N | 37_L | 1.083 | 0.96 | |
| 261_G | 281_I | 1.072 | 0.95 | |
| 165_M | 178_L | 1.071 | 0.95 | |
| 79_M | 110_K | 1.069 | 0.95 | |
| 45_G | 55_R | 1.068 | 0.95 | |
| 165_M | 180_T | 1.058 | 0.95 | |
| 77_S | 174_G | 1.048 | 0.94 | |
| 207_L | 278_H | 1.048 | 0.94 | |
| 86_Q | 94_V | 1.046 | 0.94 | |
| 80_I | 103_F | 1.046 | 0.94 | |
| 182_E | 194_D | 1.044 | 0.94 | |
| 114_E | 139_L | 1.033 | 0.94 | |
| 80_I | 100_H | 1.022 | 0.93 | |
| 78_Q | 273_R | 1.021 | 0.93 | |
| 211_T | 280_K | 1.015 | 0.93 | |
| 244_M | 250_L | 1.011 | 0.93 | |
| 182_E | 197_D | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4hg0A | 1 | 1 | 100 | 0.249 | Contact Map | 0.738 |
| 3lhhA | 1 | 0.5822 | 100 | 0.683 | Contact Map | 0.821 |
| 3ocoA | 2 | 0.5205 | 99.9 | 0.701 | Contact Map | 0.837 |
| 3oi8A | 2 | 0.5342 | 99.9 | 0.703 | Contact Map | 0.845 |
| 3ocmA | 2 | 0.5925 | 99.9 | 0.712 | Contact Map | 0.858 |
| 2v8qE | 1 | 0.8733 | 99.9 | 0.716 | Contact Map | 0.524 |
| 3lv9A | 1 | 0.5068 | 99.9 | 0.721 | Contact Map | 0.81 |
| 3kxrA | 1 | 0.6678 | 99.9 | 0.723 | Contact Map | 0.61 |
| 3dedA | 6 | 0.3699 | 99.9 | 0.736 | Contact Map | 0.79 |
| 2qrdG | 2 | 0.8185 | 99.9 | 0.744 | Contact Map | 0.54 |
Sequence Conservation (Image Generated using WebLogo v3)