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OPENSEQ.org

PINR - Putative DNA-invertase from lambdoid prophage Rac
UniProt: P0ADI0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13372
Length: 196 (188)
Sequences: 4105
Seq/Len: 21.84

PINR
Paralog alert: 0.63 [within 20: 0.19] - ratio of genomes with paralogs
Cluster includes: PINE PINQ PINR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_G 55_R 3.924 1.00
37_I 59_R 3.657 1.00
56_L 66_L 2.909 1.00
39_E 52_G 2.907 1.00
163_R 176_E 2.849 1.00
8_C 21_R 2.511 1.00
124_E 131_R 2.449 1.00
21_R 25_E 2.255 1.00
88_L 93_I 2.254 1.00
112_M 123_F 2.142 1.00
138_R 142_A 2.061 1.00
97_C 100_L 2.035 1.00
78_A 115_Q 2.033 1.00
159_V 163_R 2.01 1.00
171_S 175_R 2.003 1.00
163_R 168_V 1.97 1.00
6_A 24_I 1.935 1.00
122_E 126_D 1.89 1.00
21_R 36_I 1.884 1.00
111_K 126_D 1.851 1.00
115_Q 119_A 1.843 1.00
111_K 122_E 1.832 1.00
79_M 83_K 1.814 1.00
12_T 15_Q 1.795 1.00
60_L 66_L 1.795 1.00
5_F 56_L 1.771 1.00
168_V 176_E 1.749 1.00
132_T 136_I 1.748 1.00
129_L 133_H 1.738 1.00
78_A 118_S 1.726 1.00
112_M 119_A 1.716 1.00
21_R 38_E 1.705 1.00
139_A 144_K 1.661 1.00
53_F 84_T 1.638 1.00
87_Q 91_T 1.612 1.00
22_R 26_S 1.605 1.00
35_Q 55_R 1.593 1.00
44_S 125_R 1.587 1.00
174_A 184_I 1.56 1.00
78_A 82_R 1.514 1.00
81_I 118_S 1.502 1.00
60_L 93_I 1.5 1.00
125_R 128_L 1.482 1.00
89_T 111_K 1.477 1.00
4_I 29_F 1.432 1.00
153_N 156_Q 1.417 1.00
181_R 185_L 1.407 0.99
82_R 115_Q 1.405 0.99
137_V 141_G 1.398 0.99
5_F 59_R 1.396 0.99
10_I 15_Q 1.38 0.99
79_M 86_E 1.349 0.99
164_I 173_I 1.299 0.99
107_S 110_G 1.294 0.99
25_E 36_I 1.291 0.99
72_D 121_A 1.286 0.99
135_G 139_A 1.282 0.99
86_E 90_E 1.268 0.99
171_S 181_R 1.244 0.98
85_V 114_M 1.228 0.98
169_S 172_A 1.217 0.98
168_V 172_A 1.211 0.98
185_L 189_A 1.209 0.98
24_I 67_I 1.206 0.98
49_E 54_N 1.193 0.98
6_A 36_I 1.188 0.98
162_E 166_S 1.184 0.98
68_V 95_V 1.174 0.98
184_I 187_A 1.166 0.97
133_H 136_I 1.163 0.97
160_V 184_I 1.163 0.97
69_T 134_S 1.153 0.97
41_I 51_P 1.137 0.97
8_C 17_T 1.137 0.97
164_I 188_K 1.136 0.97
136_I 146_F 1.133 0.97
68_V 97_C 1.116 0.96
163_R 166_S 1.113 0.96
75_G 81_I 1.103 0.96
37_I 56_L 1.102 0.96
157_K 160_V 1.094 0.96
127_L 131_R 1.082 0.96
136_I 140_R 1.079 0.95
53_F 56_L 1.064 0.95
65_Q 96_H 1.063 0.95
138_R 141_G 1.04 0.94
112_M 120_V 1.039 0.94
163_R 173_I 1.03 0.94
170_I 185_L 1.026 0.94
160_V 173_I 1.023 0.93
112_M 116_V 1.022 0.93
70_K 99_A 1.018 0.93
4_I 96_H 1.016 0.93
128_L 132_T 1.015 0.93
72_D 131_R 1.009 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1gdtA20.93371000.155Contact Map0.664
3uj3X10.95411000.176Contact Map0.4
2r0qC40.96431000.197Contact Map0.659
4bqqA20.97961000.282Contact Map0.675
3g13A20.78061000.356Contact Map0.567
3guvA10.76531000.364Contact Map0.529
2gm5A40.70921000.382Contact Map0.854
3lhkA40.73471000.461Contact Map0.623
3ilxA20.663399.90.47Contact Map0.604
3bvpA20.632799.90.471Contact Map0.625

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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