| UniProt: | P0ADG4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10983 | ||
| Length: | 267 (259) | ||
| Sequences: | 4778 | ||
| Seq/Len: | 18.45 |
| SUHB
Paralog alert: 0.66 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: CYSQ SUHB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 220_V | 225_G | 4.572 | 1.00 | |
| 117_Y | 124_L | 3.588 | 1.00 | |
| 228_S | 250_V | 3.138 | 1.00 | |
| 79_V | 107_I | 3.008 | 1.00 | |
| 78_D | 108_K | 2.981 | 1.00 | |
| 118_D | 121_R | 2.862 | 1.00 | |
| 217_E | 221_R | 2.795 | 1.00 | |
| 128_T | 131_Q | 2.775 | 1.00 | |
| 132_G | 222_E | 2.672 | 1.00 | |
| 14_K | 54_T | 2.492 | 1.00 | |
| 11_A | 54_T | 2.443 | 1.00 | |
| 229_D | 233_G | 2.341 | 1.00 | |
| 154_A | 200_V | 2.325 | 1.00 | |
| 16_G | 117_Y | 2.195 | 1.00 | |
| 18_L | 50_V | 2.175 | 1.00 | |
| 42_N | 46_A | 2.151 | 1.00 | |
| 59_Y | 62_H | 2.092 | 1.00 | |
| 110_R | 129_R | 2.091 | 1.00 | |
| 82_V | 106_R | 2.057 | 1.00 | |
| 12_A | 103_I | 2.028 | 1.00 | |
| 32_S | 45_K | 2.024 | 1.00 | |
| 49_A | 53_D | 2.015 | 1.00 | |
| 202_G | 253_M | 1.981 | 1.00 | |
| 218_L | 222_E | 1.973 | 1.00 | |
| 116_V | 193_A | 1.964 | 1.00 | |
| 127_A | 222_E | 1.929 | 1.00 | |
| 114_A | 218_L | 1.91 | 1.00 | |
| 80_Q | 106_R | 1.898 | 1.00 | |
| 52_I | 64_I | 1.897 | 1.00 | |
| 125_F | 197_A | 1.867 | 1.00 | |
| 107_I | 112_E | 1.863 | 1.00 | |
| 48_E | 66_T | 1.839 | 1.00 | |
| 54_T | 57_K | 1.828 | 1.00 | |
| 99_F | 120_M | 1.812 | 1.00 | |
| 123_E | 199_R | 1.789 | 1.00 | |
| 19_I | 86_L | 1.78 | 1.00 | |
| 193_A | 219_L | 1.779 | 1.00 | |
| 106_R | 111_T | 1.774 | 1.00 | |
| 104_A | 214_A | 1.766 | 1.00 | |
| 83_I | 103_I | 1.743 | 1.00 | |
| 50_V | 54_T | 1.739 | 1.00 | |
| 110_R | 221_R | 1.685 | 1.00 | |
| 31_A | 34_K | 1.669 | 1.00 | |
| 126_T | 134_Q | 1.658 | 1.00 | |
| 52_I | 56_R | 1.644 | 1.00 | |
| 79_V | 105_V | 1.644 | 1.00 | |
| 62_H | 79_V | 1.624 | 1.00 | |
| 41_T | 93_I | 1.621 | 1.00 | |
| 12_A | 115_V | 1.589 | 1.00 | |
| 134_Q | 139_R | 1.548 | 1.00 | |
| 135_L | 197_A | 1.544 | 1.00 | |
| 147_D | 150_G | 1.538 | 1.00 | |
| 78_D | 107_I | 1.532 | 1.00 | |
| 130_G | 222_E | 1.528 | 1.00 | |
| 118_D | 190_L | 1.527 | 1.00 | |
| 55_I | 62_H | 1.513 | 1.00 | |
| 22_N | 43_V | 1.509 | 1.00 | |
| 20_A | 120_M | 1.505 | 1.00 | |
| 7_I | 11_A | 1.498 | 1.00 | |
| 8_A | 81_W | 1.477 | 1.00 | |
| 23_Y | 99_F | 1.462 | 1.00 | |
| 133_A | 140_L | 1.456 | 1.00 | |
| 51_I | 103_I | 1.453 | 1.00 | |
| 9_V | 126_T | 1.441 | 1.00 | |
| 19_I | 47_A | 1.435 | 1.00 | |
| 102_S | 189_A | 1.432 | 1.00 | |
| 81_W | 105_V | 1.389 | 0.99 | |
| 127_A | 218_L | 1.384 | 0.99 | |
| 129_R | 221_R | 1.364 | 0.99 | |
| 51_I | 83_I | 1.348 | 0.99 | |
| 117_Y | 122_N | 1.342 | 0.99 | |
| 7_I | 59_Y | 1.328 | 0.99 | |
| 47_A | 86_L | 1.305 | 0.99 | |
| 39_F | 90_T | 1.303 | 0.99 | |
| 129_R | 222_E | 1.298 | 0.99 | |
| 192_L | 244_A | 1.286 | 0.99 | |
| 151_T | 249_V | 1.283 | 0.99 | |
| 123_E | 197_A | 1.28 | 0.99 | |
| 245_G | 250_V | 1.278 | 0.99 | |
| 13_R | 124_L | 1.272 | 0.99 | |
| 62_H | 81_W | 1.258 | 0.99 | |
| 7_I | 58_S | 1.256 | 0.99 | |
| 100_A | 189_A | 1.235 | 0.98 | |
| 82_V | 214_A | 1.229 | 0.98 | |
| 39_F | 93_I | 1.225 | 0.98 | |
| 47_A | 51_I | 1.223 | 0.98 | |
| 226_I | 251_K | 1.177 | 0.98 | |
| 166_T | 173_G | 1.173 | 0.98 | |
| 44_D | 68_E | 1.168 | 0.97 | |
| 192_L | 216_G | 1.166 | 0.97 | |
| 252_A | 255_A | 1.159 | 0.97 | |
| 251_K | 255_A | 1.153 | 0.97 | |
| 10_R | 58_S | 1.151 | 0.97 | |
| 105_V | 113_V | 1.143 | 0.97 | |
| 45_K | 49_A | 1.139 | 0.97 | |
| 143_S | 201_D | 1.136 | 0.97 | |
| 53_D | 57_K | 1.132 | 0.97 | |
| 194_Y | 199_R | 1.115 | 0.96 | |
| 19_I | 92_F | 1.11 | 0.96 | |
| 116_V | 219_L | 1.11 | 0.96 | |
| 151_T | 201_D | 1.103 | 0.96 | |
| 68_E | 89_T | 1.099 | 0.96 | |
| 52_I | 66_T | 1.098 | 0.96 | |
| 52_I | 69_S | 1.094 | 0.96 | |
| 20_A | 99_F | 1.094 | 0.96 | |
| 192_L | 220_V | 1.086 | 0.96 | |
| 104_A | 218_L | 1.086 | 0.96 | |
| 96_L | 185_T | 1.084 | 0.96 | |
| 140_L | 197_A | 1.083 | 0.96 | |
| 104_A | 111_T | 1.076 | 0.95 | |
| 153_L | 202_G | 1.075 | 0.95 | |
| 142_G | 223_A | 1.073 | 0.95 | |
| 113_V | 128_T | 1.07 | 0.95 | |
| 19_I | 99_F | 1.062 | 0.95 | |
| 55_I | 59_Y | 1.061 | 0.95 | |
| 175_L | 253_M | 1.052 | 0.95 | |
| 46_A | 49_A | 1.051 | 0.94 | |
| 41_T | 89_T | 1.049 | 0.94 | |
| 123_E | 135_L | 1.043 | 0.94 | |
| 8_A | 12_A | 1.028 | 0.94 | |
| 10_R | 14_K | 1.027 | 0.94 | |
| 48_E | 52_I | 1.026 | 0.94 | |
| 170_N | 173_G | 1.025 | 0.93 | |
| 220_V | 244_A | 1.021 | 0.93 | |
| 229_D | 232_G | 1.019 | 0.93 | |
| 48_E | 69_S | 1.017 | 0.93 | |
| 111_T | 217_E | 1.016 | 0.93 | |
| 54_T | 58_S | 1.007 | 0.93 | |
| 9_V | 13_R | 1.004 | 0.93 | |
| 5_L | 126_T | 1.003 | 0.93 | |
| 111_T | 218_L | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2qflA | 1 | 1 | 100 | 0.078 | Contact Map | 0.798 |
| 3lv0A | 2 | 0.9775 | 100 | 0.093 | Contact Map | 0.856 |
| 2pcrA | 4 | 0.9775 | 100 | 0.103 | Contact Map | 0.815 |
| 2q74A | 3 | 0.9925 | 100 | 0.122 | Contact Map | 0.734 |
| 2p3nA | 4 | 0.9513 | 100 | 0.127 | Contact Map | 0.884 |
| 2fvzA | 4 | 0.9813 | 100 | 0.13 | Contact Map | 0.854 |
| 3t0jA | 4 | 0.9738 | 100 | 0.135 | Contact Map | 0.805 |
| 4g62A | 2 | 0.9625 | 100 | 0.135 | Contact Map | 0.789 |
| 4i3yA | 2 | 0.9625 | 100 | 0.136 | Contact Map | 0.789 |
| 2bjiA | 2 | 0.9813 | 100 | 0.141 | Contact Map | 0.755 |
Sequence Conservation (Image Generated using WebLogo v3)