| UniProt: | P0ACS5 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11969 | ||
| Length: | 141 (127) | ||
| Sequences: | 4446 | ||
| Seq/Len: | 35.01 |
| ZNTR
Paralog alert: 0.72 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: CUER SOXR ZNTR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 94_E | 104_Q | 4.693 | 1.00 | |
| 90_L | 108_Q | 3.57 | 1.00 | |
| 97_I | 101_Q | 3.38 | 1.00 | |
| 41_T | 44_D | 2.978 | 1.00 | |
| 20_Y | 24_Q | 2.971 | 1.00 | |
| 87_Q | 111_N | 2.909 | 1.00 | |
| 16_D | 23_K | 2.415 | 1.00 | |
| 89_R | 92_E | 2.309 | 1.00 | |
| 4_I | 19_R | 2.157 | 1.00 | |
| 97_I | 100_L | 2.128 | 1.00 | |
| 90_L | 104_Q | 2.036 | 1.00 | |
| 94_E | 108_Q | 1.954 | 1.00 | |
| 93_V | 100_L | 1.939 | 1.00 | |
| 15_P | 19_R | 1.907 | 1.00 | |
| 55_R | 61_L | 1.859 | 1.00 | |
| 101_Q | 104_Q | 1.824 | 1.00 | |
| 86_V | 111_N | 1.796 | 1.00 | |
| 24_Q | 65_R | 1.778 | 1.00 | |
| 33_T | 39_L | 1.765 | 1.00 | |
| 47_R | 73_D | 1.734 | 1.00 | |
| 5_G | 9_K | 1.632 | 1.00 | |
| 63_S | 89_R | 1.604 | 1.00 | |
| 7_L | 48_L | 1.585 | 1.00 | |
| 95_A | 99_E | 1.576 | 1.00 | |
| 90_L | 111_N | 1.501 | 1.00 | |
| 18_I | 40_Y | 1.45 | 1.00 | |
| 87_Q | 115_C | 1.445 | 1.00 | |
| 96_R | 99_E | 1.432 | 1.00 | |
| 2_Y | 39_L | 1.419 | 1.00 | |
| 90_L | 94_E | 1.395 | 0.99 | |
| 7_L | 44_D | 1.368 | 0.99 | |
| 31_V | 41_T | 1.32 | 0.99 | |
| 98_A | 101_Q | 1.31 | 0.99 | |
| 86_V | 107_L | 1.31 | 0.99 | |
| 52_R | 55_R | 1.306 | 0.99 | |
| 104_Q | 108_Q | 1.306 | 0.99 | |
| 6_E | 9_K | 1.298 | 0.99 | |
| 5_G | 15_P | 1.286 | 0.99 | |
| 97_I | 104_Q | 1.271 | 0.99 | |
| 60_S | 63_S | 1.246 | 0.98 | |
| 26_M | 51_I | 1.226 | 0.98 | |
| 7_L | 45_L | 1.223 | 0.98 | |
| 14_T | 17_T | 1.217 | 0.98 | |
| 47_R | 68_L | 1.201 | 0.98 | |
| 11_A | 45_L | 1.195 | 0.98 | |
| 92_E | 96_R | 1.185 | 0.98 | |
| 83_K | 87_Q | 1.162 | 0.97 | |
| 81_E | 84_G | 1.149 | 0.97 | |
| 93_V | 104_Q | 1.146 | 0.97 | |
| 17_T | 20_Y | 1.143 | 0.97 | |
| 92_E | 95_A | 1.138 | 0.97 | |
| 6_E | 10_M | 1.134 | 0.97 | |
| 95_A | 98_A | 1.064 | 0.95 | |
| 91_Q | 94_E | 1.058 | 0.95 | |
| 100_L | 104_Q | 1.053 | 0.95 | |
| 22_E | 27_M | 1.049 | 0.94 | |
| 3_R | 37_F | 1.047 | 0.94 | |
| 63_S | 92_E | 1.046 | 0.94 | |
| 24_Q | 62_E | 1.042 | 0.94 | |
| 109_R | 113_A | 1.04 | 0.94 | |
| 3_R | 39_L | 1.04 | 0.94 | |
| 18_I | 48_L | 1.04 | 0.94 | |
| 22_E | 30_E | 1.014 | 0.93 | |
| 3_R | 6_E | 1.014 | 0.93 | |
| 98_A | 102_S | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1q06A | 2 | 0.9574 | 100 | 0.213 | Contact Map | 0.789 |
| 2dg6A | 1 | 0.9716 | 100 | 0.246 | Contact Map | 0.401 |
| 3hh0A | 4 | 0.9574 | 100 | 0.259 | Contact Map | 0.802 |
| 3gp4A | 2 | 0.9645 | 100 | 0.259 | Contact Map | 0.823 |
| 2zhgA | 1 | 0.9645 | 100 | 0.266 | Contact Map | 0.485 |
| 3gpvA | 2 | 0.9433 | 100 | 0.271 | Contact Map | 0.783 |
| 3qaoA | 1 | 0.9433 | 99.9 | 0.305 | Contact Map | 0.512 |
| 1r8dA | 2 | 0.766 | 99.9 | 0.319 | Contact Map | 0.824 |
| 2vz4A | 1 | 0.766 | 99.9 | 0.327 | Contact Map | 0.469 |
| 1r8eA | 1 | 0.9504 | 99.9 | 0.36 | Contact Map | 0.493 |
Sequence Conservation (Image Generated using WebLogo v3)