| UniProt: | P0ACS2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10957 | ||
| Length: | 154 (126) | ||
| Sequences: | 2215 | ||
| Seq/Len: | 17.58 |
| SOXR
Paralog alert: 0.79 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: CUER SOXR ZNTR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 103_D | 113_R | 5.599 | 1.00 | |
| 30_F | 34_K | 3.447 | 1.00 | |
| 50_K | 53_V | 2.564 | 1.00 | |
| 26_S | 33_S | 2.386 | 1.00 | |
| 106_I | 110_V | 2.246 | 1.00 | |
| 110_V | 113_R | 2.245 | 1.00 | |
| 56_Y | 81_P | 2.205 | 1.00 | |
| 99_R | 117_D | 2.204 | 1.00 | |
| 34_K | 74_G | 2.194 | 1.00 | |
| 102_L | 109_L | 2.02 | 1.00 | |
| 103_D | 117_D | 1.935 | 1.00 | |
| 14_P | 29_H | 1.909 | 1.00 | |
| 17_V | 53_V | 1.87 | 1.00 | |
| 113_R | 117_D | 1.857 | 1.00 | |
| 99_R | 120_I | 1.765 | 1.00 | |
| 24_A | 27_A | 1.725 | 1.00 | |
| 96_S | 120_I | 1.647 | 1.00 | |
| 104_R | 108_T | 1.583 | 1.00 | |
| 62_I | 108_T | 1.544 | 1.00 | |
| 95_S | 120_I | 1.542 | 1.00 | |
| 101_E | 104_R | 1.483 | 1.00 | |
| 16_E | 19_K | 1.479 | 1.00 | |
| 27_A | 30_F | 1.461 | 1.00 | |
| 64_Q | 70_L | 1.456 | 1.00 | |
| 25_V | 29_H | 1.448 | 1.00 | |
| 106_I | 109_L | 1.438 | 1.00 | |
| 107_H | 110_V | 1.435 | 1.00 | |
| 92_K | 96_S | 1.401 | 0.99 | |
| 91_W | 95_S | 1.401 | 0.99 | |
| 87_S | 90_E | 1.394 | 0.99 | |
| 99_R | 102_L | 1.377 | 0.99 | |
| 42_N | 48_R | 1.372 | 0.99 | |
| 90_E | 93_Q | 1.371 | 0.99 | |
| 56_Y | 77_F | 1.37 | 0.99 | |
| 71_A | 74_G | 1.363 | 0.99 | |
| 101_E | 105_R | 1.324 | 0.99 | |
| 65_R | 108_T | 1.322 | 0.99 | |
| 21_S | 28_L | 1.303 | 0.99 | |
| 60_I | 73_I | 1.301 | 0.99 | |
| 61_K | 64_Q | 1.291 | 0.99 | |
| 20_R | 54_L | 1.264 | 0.99 | |
| 99_R | 113_R | 1.261 | 0.99 | |
| 72_T | 98_W | 1.257 | 0.99 | |
| 104_R | 107_H | 1.219 | 0.98 | |
| 12_L | 48_R | 1.208 | 0.98 | |
| 63_A | 68_I | 1.194 | 0.98 | |
| 64_Q | 98_W | 1.192 | 0.98 | |
| 16_E | 20_R | 1.185 | 0.98 | |
| 28_L | 57_V | 1.178 | 0.98 | |
| 74_G | 78_G | 1.157 | 0.97 | |
| 17_V | 37_I | 1.15 | 0.97 | |
| 13_T | 48_R | 1.144 | 0.97 | |
| 119_C | 132_L | 1.143 | 0.97 | |
| 36_L | 60_I | 1.13 | 0.97 | |
| 69_P | 72_T | 1.109 | 0.96 | |
| 15_G | 25_V | 1.107 | 0.96 | |
| 44_G | 48_R | 1.096 | 0.96 | |
| 110_V | 114_D | 1.067 | 0.95 | |
| 102_L | 106_I | 1.035 | 0.94 | |
| 51_R | 55_R | 1.021 | 0.93 | |
| 13_T | 46_Q | 1.01 | 0.93 | |
| 93_Q | 97_Q | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2zhgA | 1 | 1 | 100 | 0.272 | Contact Map | 0.52 |
| 1q06A | 2 | 0.8636 | 100 | 0.399 | Contact Map | 0.699 |
| 2dg6A | 1 | 0.9221 | 100 | 0.42 | Contact Map | 0.514 |
| 3gpvA | 2 | 0.9091 | 100 | 0.425 | Contact Map | 0.74 |
| 3hh0A | 4 | 0.9156 | 100 | 0.436 | Contact Map | 0.743 |
| 3gp4A | 2 | 0.8896 | 100 | 0.437 | Contact Map | 0.787 |
| 3qaoA | 1 | 0.9026 | 99.9 | 0.484 | Contact Map | 0.544 |
| 1r8dA | 2 | 0.7013 | 99.9 | 0.485 | Contact Map | 0.782 |
| 2vz4A | 1 | 0.6948 | 99.9 | 0.486 | Contact Map | 0.482 |
| 1r8eA | 1 | 0.9091 | 99.9 | 0.503 | Contact Map | 0.496 |
Sequence Conservation (Image Generated using WebLogo v3)