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OPENSEQ.org

DBHB - DNA-binding protein HU-beta
UniProt: P0ACF4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10467
Length: 90 (90)
Sequences: 2951
Seq/Len: 32.79

DBHB
Paralog alert: 0.56 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: DBHA DBHB IHFA IHFB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_K 78_S 3.595 1.00
59_T 68_E 3.057 1.00
57_A 70_T 2.841 1.00
22_G 26_D 2.818 1.00
54_E 75_K 2.715 1.00
35_S 40_D 2.55 1.00
61_R 66_G 2.511 1.00
60_G 71_I 2.505 1.00
8_D 18_K 2.397 1.00
83_K 87_D 2.392 1.00
20_A 23_R 2.237 1.00
10_I 25_L 2.206 1.00
59_T 70_T 2.192 1.00
52_V 75_K 2.085 1.00
55_R 76_V 1.932 1.00
28_I 32_V 1.752 1.00
61_R 68_E 1.741 1.00
36_L 85_L 1.595 1.00
51_A 80_R 1.558 1.00
41_D 51_A 1.497 1.00
9_K 13_G 1.484 1.00
17_S 20_A 1.482 1.00
19_A 23_R 1.482 1.00
36_L 52_V 1.464 1.00
41_D 49_T 1.459 1.00
21_A 24_A 1.413 1.00
45_V 82_G 1.401 0.99
54_E 73_A 1.368 0.99
33_T 85_L 1.283 0.99
57_A 73_A 1.263 0.99
32_V 42_V 1.252 0.99
13_G 34_E 1.251 0.99
64_Q 67_K 1.234 0.98
48_G 79_F 1.2 0.98
9_K 31_S 1.154 0.97
10_I 28_I 1.121 0.97
37_K 88_A 1.104 0.96
9_K 12_A 1.083 0.96
16_I 21_A 1.075 0.95
8_D 12_A 1.042 0.94
30_A 33_T 1.032 0.94
47_F 50_F 1.023 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2o97B1199.90.052Contact Map0.637
1mulA1199.90.056Contact Map0.802
2iieA1199.90.056Contact Map0.785
1b8zA2199.90.057Contact Map0.834
1exeA2199.90.061Contact Map0.656
1p71A2199.90.061Contact Map0.842
3c4iA2199.90.063Contact Map0.877
3rhiA4199.90.063Contact Map0.941
1owfB1199.90.065Contact Map0.687
1owfA1199.90.068Contact Map0.7

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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