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OPENSEQ.org
YGHB - Inner membrane protein YghB
UniProt: P0AA60 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11824
Length: 219 (215)
Sequences: 1653
Seq/Len: 7.69
YGHB
Paralog alert: 0.49 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DEDA YABI YGHB YOHD YQJA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
121_H 124_L 3.072 1.00
67_D 70_P 3.058 1.00
75_L 165_V 2.293 1.00
84_W 150_N 2.282 1.00
115_T 119_D 2.278 1.00
107_P 110_Y 2.232 1.00
76_T 162_L 2.224 1.00
95_N 115_T 2.097 1.00
33_F 77_A 2.028 1.00
127_L 159_L 2.008 1.00
72_I 166_S 1.999 1.00
37_F 85_L 1.977 1.00
61_I 173_Y 1.862 1.00
54_L 169_T 1.778 1.00
57_A 71_T 1.765 1.00
37_F 81_L 1.705 1.00
190_T 194_I 1.644 1.00
112_Q 116_C 1.602 1.00
62_A 177_M 1.574 1.00
80_S 158_W 1.542 1.00
109_K 113_R 1.535 1.00
36_L 78_A 1.532 1.00
54_L 58_G 1.515 1.00
208_L 212_I 1.515 1.00
154_Q 158_W 1.508 0.99
129_G 139_L 1.505 0.99
68_F 169_T 1.505 0.99
149_P 152_R 1.486 0.99
86_S 137_T 1.46 0.99
1_M 4_I 1.439 0.99
83_C 150_N 1.434 0.99
80_S 157_N 1.412 0.99
157_N 161_G 1.398 0.99
192_L 196_P 1.377 0.99
68_F 72_I 1.374 0.99
114_A 125_A 1.373 0.99
72_I 170_S 1.371 0.99
76_T 80_S 1.364 0.99
74_I 78_A 1.362 0.99
39_E 50_G 1.361 0.99
69_L 170_S 1.355 0.99
123_L 152_R 1.351 0.99
91_R 147_G 1.351 0.99
72_I 169_T 1.348 0.99
140_P 157_N 1.344 0.99
46_S 86_S 1.329 0.98
182_K 186_D 1.314 0.98
206_G 210_V 1.311 0.98
84_W 154_Q 1.31 0.98
71_T 169_T 1.306 0.98
2_A 5_Q 1.283 0.98
81_L 85_L 1.279 0.98
73_A 77_A 1.278 0.98
79_A 161_G 1.274 0.98
24_I 31_V 1.272 0.98
212_I 216_Y 1.26 0.98
32_M 75_L 1.258 0.98
179_P 183_R 1.252 0.97
108_A 112_Q 1.252 0.97
132_L 135_V 1.234 0.97
39_E 130_R 1.231 0.97
114_A 146_S 1.229 0.97
210_V 213_K 1.202 0.97
166_S 170_S 1.19 0.96
209_F 213_K 1.188 0.96
211_V 214_K 1.179 0.96
68_F 170_S 1.178 0.96
36_L 165_V 1.175 0.96
150_N 154_Q 1.161 0.96
38_L 45_A 1.151 0.95
195_L 198_A 1.138 0.95
9_A 13_Q 1.137 0.95
208_L 211_V 1.135 0.95
118_F 139_L 1.132 0.95
83_C 168_V 1.123 0.94
125_A 148_L 1.112 0.94
61_I 68_F 1.111 0.94
56_L 185_E 1.111 0.94
62_A 173_Y 1.105 0.94
36_L 54_L 1.103 0.94
118_F 143_A 1.099 0.93
206_G 209_F 1.094 0.93
88_I 92_W 1.094 0.93
184_H 187_Q 1.088 0.93
153_F 157_N 1.079 0.93
209_F 212_I 1.075 0.92
116_C 155_F 1.074 0.92
207_T 213_K 1.07 0.92
57_A 61_I 1.067 0.92
51_D 136_R 1.067 0.92
41_G 46_S 1.067 0.92
205_L 208_L 1.063 0.92
92_W 96_T 1.052 0.91
103_L 106_L 1.049 0.91
57_A 66_M 1.049 0.91
70_P 73_A 1.045 0.91
99_V 112_Q 1.043 0.91
45_A 86_S 1.04 0.91
40_N 83_C 1.04 0.91
208_L 216_Y 1.038 0.91
66_M 71_T 1.03 0.90
84_W 157_N 1.029 0.90
36_L 75_L 1.029 0.90
210_V 214_K 1.029 0.90
2_A 213_K 1.029 0.90
35_T 48_L 1.023 0.90
54_L 75_L 1.018 0.89
86_S 141_T 1.012 0.89
213_K 216_Y 1.011 0.89
38_L 42_L 1.005 0.89
211_V 216_Y 1.002 0.88
56_L 59_A 1.001 0.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2l2tA20.196321.10.945Contact Map0.31
2kluA10.187215.40.948Contact Map0.215
2m20A20.164414.10.949Contact Map0.501
1fftB20.333313.40.949Contact Map0.209
2ks1B10.196311.10.951Contact Map0.197
2jwaA20.200910.90.951Contact Map0.361
4b19A10.1376.60.956Contact Map0.416
2l9uA20.17354.80.959Contact Map0.442
2lbgA10.12334.70.959Contact Map0.02
2kv5A10.14614.30.96Contact Map0.52
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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