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OPENSEQ.org

PTSO - Phosphocarrier protein NPr
UniProt: P0A9N0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12147
Length: 90 (88)
Sequences: 1821
Seq/Len: 20.69

PTSO
Paralog alert: 0.51 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PTHP PTSO
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
6_T 62_Q 3.312 1.00
67_A 76_L 2.686 1.00
32_A 71_Q 2.536 1.00
31_D 70_P 2.337 1.00
7_V 80_I 2.098 1.00
5_Q 80_I 2.083 1.00
23_L 79_V 2.073 1.00
73_E 77_A 2.057 1.00
30_F 78_A 2.037 1.00
31_D 71_Q 1.952 1.00
26_L 29_G 1.945 1.00
8_E 62_Q 1.848 1.00
85_S 88_D 1.806 1.00
4_K 64_E 1.78 1.00
26_L 78_A 1.752 1.00
38_N 61_R 1.733 1.00
6_T 64_E 1.649 1.00
30_F 75_A 1.604 1.00
4_K 66_E 1.589 1.00
35_L 43_E 1.535 1.00
81_A 85_S 1.526 1.00
77_A 81_A 1.525 1.00
80_I 84_N 1.518 1.00
23_L 46_A 1.466 1.00
37_R 66_E 1.453 1.00
37_R 43_E 1.415 1.00
37_R 64_E 1.413 1.00
3_V 73_E 1.384 0.99
44_A 55_L 1.32 0.99
5_Q 77_A 1.268 0.99
43_E 66_E 1.258 0.99
71_Q 74_E 1.25 0.99
74_E 78_A 1.244 0.98
12_K 59_K 1.215 0.98
3_V 76_L 1.171 0.98
57_S 63_I 1.153 0.97
37_R 41_G 1.141 0.97
27_M 79_V 1.139 0.97
34_V 75_A 1.123 0.97
23_L 36_L 1.121 0.97
10_T 86_G 1.116 0.96
33_E 68_T 1.102 0.96
44_A 50_I 1.094 0.96
58_A 61_R 1.076 0.95
74_E 77_A 1.044 0.94
11_N 87_F 1.039 0.94
32_A 67_A 1.035 0.94
82_L 87_F 1.011 0.93
45_E 48_S 1.008 0.93
9_I 57_S 1.005 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3le1A20.977899.90.057Contact Map0.841
1pchA10.966799.90.067Contact Map0.761
1sphA20.966799.90.068Contact Map0.836
1y51A30.966799.90.068Contact Map0.737
1kklH30.977899.90.079Contact Map0.831
1ptfA10.966799.90.086Contact Map0.753
1ka5A10.977899.90.102Contact Map0.809
3ihsA20.922299.90.107Contact Map0.848
3ccdA20.944499.90.113Contact Map0.827
2jpiA10.933.70.878Contact Map0.126

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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