| UniProt: | P0A8U2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11650 | ||
| Length: | 266 (217) | ||
| Sequences: | 3643 | ||
| Seq/Len: | 16.79 |
| YAFD
Paralog alert: 0.62 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: EX3 YAFD YBHP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 45_R | 258_E | 6.045 | 1.00 | |
| 74_L | 188_A | 4.209 | 1.00 | |
| 240_S | 260_S | 3.482 | 1.00 | |
| 112_T | 140_T | 3.303 | 1.00 | |
| 245_L | 256_L | 2.708 | 1.00 | |
| 75_L | 78_A | 2.569 | 1.00 | |
| 243_S | 256_L | 2.493 | 1.00 | |
| 48_V | 255_L | 2.399 | 1.00 | |
| 232_V | 257_V | 2.397 | 1.00 | |
| 47_L | 256_L | 2.378 | 1.00 | |
| 74_L | 152_V | 2.373 | 1.00 | |
| 184_P | 236_G | 2.301 | 1.00 | |
| 241_E | 258_E | 2.223 | 1.00 | |
| 71_H | 115_A | 2.15 | 1.00 | |
| 112_T | 154_N | 2.11 | 1.00 | |
| 47_L | 70_A | 2.097 | 1.00 | |
| 143_P | 149_L | 2.084 | 1.00 | |
| 214_V | 234_Y | 2.069 | 1.00 | |
| 118_P | 142_Y | 2.028 | 1.00 | |
| 141_V | 151_M | 2.017 | 1.00 | |
| 74_L | 154_N | 2.015 | 1.00 | |
| 72_L | 152_V | 1.897 | 1.00 | |
| 94_A | 117_H | 1.88 | 1.00 | |
| 234_Y | 259_F | 1.827 | 1.00 | |
| 114_S | 117_H | 1.807 | 1.00 | |
| 141_V | 183_G | 1.783 | 1.00 | |
| 213_Q | 228_P | 1.7 | 1.00 | |
| 76_Q | 154_N | 1.661 | 1.00 | |
| 47_L | 68_K | 1.641 | 1.00 | |
| 212_R | 218_D | 1.63 | 1.00 | |
| 48_V | 76_Q | 1.627 | 1.00 | |
| 45_R | 256_L | 1.618 | 1.00 | |
| 240_S | 258_E | 1.566 | 1.00 | |
| 238_N | 260_S | 1.562 | 1.00 | |
| 46_I | 186_I | 1.557 | 1.00 | |
| 43_R | 258_E | 1.519 | 1.00 | |
| 157_A | 170_Q | 1.497 | 1.00 | |
| 137_A | 153_V | 1.492 | 1.00 | |
| 175_G | 179_A | 1.474 | 1.00 | |
| 157_A | 171_L | 1.445 | 1.00 | |
| 234_Y | 239_V | 1.425 | 1.00 | |
| 145_P | 148_R | 1.421 | 1.00 | |
| 70_A | 73_V | 1.417 | 1.00 | |
| 151_M | 183_G | 1.39 | 0.99 | |
| 139_V | 151_M | 1.389 | 0.99 | |
| 141_V | 149_L | 1.385 | 0.99 | |
| 72_L | 140_T | 1.385 | 0.99 | |
| 96_D | 114_S | 1.371 | 0.99 | |
| 73_V | 113_L | 1.362 | 0.99 | |
| 185_V | 211_L | 1.36 | 0.99 | |
| 54_Q | 80_T | 1.352 | 0.99 | |
| 232_V | 259_F | 1.345 | 0.99 | |
| 63_L | 88_A | 1.337 | 0.99 | |
| 237_L | 259_F | 1.33 | 0.99 | |
| 68_K | 245_L | 1.324 | 0.99 | |
| 116_A | 142_Y | 1.311 | 0.99 | |
| 214_V | 239_V | 1.298 | 0.99 | |
| 178_I | 211_L | 1.286 | 0.99 | |
| 169_K | 173_P | 1.273 | 0.99 | |
| 72_L | 142_Y | 1.248 | 0.99 | |
| 77_E | 192_N | 1.238 | 0.98 | |
| 62_V | 65_N | 1.235 | 0.98 | |
| 188_A | 232_V | 1.231 | 0.98 | |
| 64_K | 91_N | 1.231 | 0.98 | |
| 195_S | 203_Y | 1.193 | 0.98 | |
| 152_V | 188_A | 1.189 | 0.98 | |
| 155_I | 174_I | 1.178 | 0.98 | |
| 77_E | 190_D | 1.176 | 0.98 | |
| 169_K | 172_L | 1.176 | 0.98 | |
| 78_A | 111_M | 1.175 | 0.98 | |
| 47_L | 73_V | 1.17 | 0.97 | |
| 153_V | 178_I | 1.165 | 0.97 | |
| 202_L | 233_F | 1.164 | 0.97 | |
| 212_R | 235_R | 1.151 | 0.97 | |
| 103_L | 127_R | 1.15 | 0.97 | |
| 155_I | 191_F | 1.147 | 0.97 | |
| 51_I | 78_A | 1.144 | 0.97 | |
| 72_L | 116_A | 1.138 | 0.97 | |
| 86_Q | 90_A | 1.127 | 0.97 | |
| 94_A | 116_A | 1.125 | 0.97 | |
| 74_L | 112_T | 1.125 | 0.97 | |
| 151_M | 185_V | 1.122 | 0.97 | |
| 49_W | 254_P | 1.108 | 0.96 | |
| 179_A | 209_M | 1.106 | 0.96 | |
| 165_D | 169_K | 1.104 | 0.96 | |
| 241_E | 256_L | 1.095 | 0.96 | |
| 172_L | 201_A | 1.083 | 0.96 | |
| 187_M | 191_F | 1.082 | 0.96 | |
| 139_V | 177_Q | 1.082 | 0.96 | |
| 204_R | 208_E | 1.079 | 0.95 | |
| 139_V | 153_V | 1.074 | 0.95 | |
| 190_D | 251_D | 1.065 | 0.95 | |
| 172_L | 176_D | 1.063 | 0.95 | |
| 114_S | 118_P | 1.055 | 0.95 | |
| 46_I | 72_L | 1.052 | 0.95 | |
| 49_W | 249_A | 1.049 | 0.94 | |
| 242_A | 257_V | 1.048 | 0.94 | |
| 218_D | 238_N | 1.039 | 0.94 | |
| 195_S | 231_F | 1.032 | 0.94 | |
| 77_E | 251_D | 1.021 | 0.93 | |
| 51_I | 54_Q | 1.021 | 0.93 | |
| 206_A | 233_F | 1.019 | 0.93 | |
| 125_R | 163_G | 1.014 | 0.93 | |
| 122_C | 137_A | 1.006 | 0.93 | |
| 64_K | 67_G | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3tebA | 2 | 0.7895 | 100 | 0.508 | Contact Map | 0.764 |
| 3mprA | 4 | 0.812 | 100 | 0.509 | Contact Map | 0.792 |
| 3g6sA | 1 | 0.8008 | 100 | 0.512 | Contact Map | 0.763 |
| 2j63A | 2 | 0.9474 | 100 | 0.52 | Contact Map | 0.783 |
| 3ngqA | 1 | 0.9398 | 100 | 0.522 | Contact Map | 0.721 |
| 4k6lF | 1 | 0.7895 | 100 | 0.522 | Contact Map | 0.58 |
| 4b8cD | 4 | 0.9887 | 100 | 0.523 | Contact Map | 0.756 |
| 1sr4B | 1 | 0.7744 | 100 | 0.523 | Contact Map | 0.588 |
| 4gz1A | 2 | 0.797 | 100 | 0.53 | Contact Map | 0.746 |
| 2f1nA | 1 | 0.8008 | 100 | 0.531 | Contact Map | 0.58 |
Sequence Conservation (Image Generated using WebLogo v3)