| UniProt: | P0A8J8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10844 | ||
| Length: | 421 (376) | ||
| Sequences: | 16607 | ||
| Seq/Len: | 44.17 |
| RHLB
Paralog alert: 0.90 [within 20: 0.15] - ratio of genomes with paralogs Cluster includes: DBPA DEAD RHLB RHLE SRMB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 301_E | 306_D | 4.145 | 1.00 | |
| 64_L | 104_A | 4.084 | 1.00 | |
| 67_T | 87_A | 3.962 | 1.00 | |
| 43_T | 195_M | 3.528 | 1.00 | |
| 17_H | 69_H | 3.385 | 1.00 | |
| 284_G | 307_L | 3.201 | 1.00 | |
| 140_G | 145_L | 3.195 | 1.00 | |
| 300_D | 304_R | 3.01 | 1.00 | |
| 47_R | 217_E | 2.983 | 1.00 | |
| 263_A | 269_C | 2.974 | 1.00 | |
| 266_K | 289_D | 2.889 | 1.00 | |
| 91_A | 100_I | 2.839 | 1.00 | |
| 35_I | 51_G | 2.823 | 1.00 | |
| 297_R | 301_E | 2.659 | 1.00 | |
| 101_H | 105_E | 2.574 | 1.00 | |
| 282_R | 308_D | 2.513 | 1.00 | |
| 116_G | 135_V | 2.411 | 1.00 | |
| 281_H | 309_I | 2.409 | 1.00 | |
| 233_E | 344_I | 2.297 | 1.00 | |
| 26_K | 110_A | 2.292 | 1.00 | |
| 344_I | 356_S | 2.256 | 1.00 | |
| 148_Y | 153_H | 2.229 | 1.00 | |
| 18_P | 22_E | 2.203 | 1.00 | |
| 259_A | 327_H | 2.185 | 1.00 | |
| 284_G | 301_E | 2.183 | 1.00 | |
| 284_G | 298_I | 2.115 | 1.00 | |
| 273_W | 283_V | 2.049 | 1.00 | |
| 273_W | 285_L | 2.029 | 1.00 | |
| 114_K | 136_D | 2.022 | 1.00 | |
| 327_H | 357_I | 1.998 | 1.00 | |
| 103_D | 106_P | 1.943 | 1.00 | |
| 324_A | 352_A | 1.943 | 1.00 | |
| 269_C | 285_L | 1.931 | 1.00 | |
| 67_T | 163_V | 1.926 | 1.00 | |
| 276_L | 311_V | 1.925 | 1.00 | |
| 232_K | 355_H | 1.924 | 1.00 | |
| 333_L | 358_S | 1.917 | 1.00 | |
| 263_A | 311_V | 1.898 | 1.00 | |
| 162_V | 183_F | 1.895 | 1.00 | |
| 12_S | 25_E | 1.86 | 1.00 | |
| 270_E | 285_L | 1.857 | 1.00 | |
| 101_H | 115_L | 1.851 | 1.00 | |
| 125_D | 129_K | 1.848 | 1.00 | |
| 316_A | 320_L | 1.844 | 1.00 | |
| 150_K | 181_W | 1.836 | 1.00 | |
| 29_F | 61_M | 1.832 | 1.00 | |
| 248_Q | 279_D | 1.824 | 1.00 | |
| 244_M | 275_H | 1.823 | 1.00 | |
| 26_K | 109_E | 1.817 | 1.00 | |
| 116_G | 130_V | 1.806 | 1.00 | |
| 233_E | 340_Y | 1.781 | 1.00 | |
| 70_Y | 161_V | 1.764 | 1.00 | |
| 123_G | 126_K | 1.733 | 1.00 | |
| 51_G | 197_F | 1.726 | 1.00 | |
| 101_H | 117_L | 1.726 | 1.00 | |
| 263_A | 272_I | 1.698 | 1.00 | |
| 88_L | 159_I | 1.684 | 1.00 | |
| 86_R | 160_Q | 1.681 | 1.00 | |
| 135_V | 138_L | 1.68 | 1.00 | |
| 20_V | 69_H | 1.67 | 1.00 | |
| 86_R | 136_D | 1.664 | 1.00 | |
| 206_R | 218_Y | 1.663 | 1.00 | |
| 104_A | 115_L | 1.648 | 1.00 | |
| 22_E | 26_K | 1.646 | 1.00 | |
| 169_R | 172_D | 1.641 | 1.00 | |
| 268_R | 332_D | 1.639 | 1.00 | |
| 42_L | 49_V | 1.626 | 1.00 | |
| 23_A | 110_A | 1.613 | 1.00 | |
| 180_R | 211_E | 1.605 | 1.00 | |
| 330_N | 358_S | 1.6 | 1.00 | |
| 273_W | 277_A | 1.599 | 1.00 | |
| 37_A | 41_P | 1.599 | 1.00 | |
| 25_E | 30_H | 1.596 | 1.00 | |
| 269_C | 287_T | 1.595 | 1.00 | |
| 67_T | 161_V | 1.58 | 1.00 | |
| 90_M | 145_L | 1.574 | 1.00 | |
| 104_A | 139_I | 1.569 | 1.00 | |
| 89_I | 104_A | 1.563 | 1.00 | |
| 22_E | 110_A | 1.553 | 1.00 | |
| 42_L | 45_A | 1.545 | 1.00 | |
| 234_E | 355_H | 1.544 | 1.00 | |
| 298_I | 307_L | 1.539 | 1.00 | |
| 42_L | 217_E | 1.537 | 1.00 | |
| 250_L | 357_I | 1.532 | 1.00 | |
| 302_F | 310_L | 1.522 | 1.00 | |
| 27_K | 106_P | 1.515 | 1.00 | |
| 46_G | 193_L | 1.505 | 1.00 | |
| 176_I | 180_R | 1.476 | 1.00 | |
| 146_I | 181_W | 1.474 | 1.00 | |
| 87_A | 161_V | 1.471 | 1.00 | |
| 70_Y | 160_Q | 1.471 | 1.00 | |
| 104_A | 137_I | 1.46 | 1.00 | |
| 273_W | 311_V | 1.458 | 1.00 | |
| 272_I | 331_Y | 1.455 | 1.00 | |
| 265_T | 268_R | 1.454 | 1.00 | |
| 259_A | 309_I | 1.447 | 1.00 | |
| 124_Y | 128_L | 1.445 | 1.00 | |
| 301_E | 307_L | 1.445 | 1.00 | |
| 296_L | 300_D | 1.431 | 1.00 | |
| 90_M | 140_G | 1.422 | 1.00 | |
| 97_A | 117_L | 1.42 | 1.00 | |
| 291_A | 294_K | 1.414 | 1.00 | |
| 63_F | 197_F | 1.413 | 1.00 | |
| 147_D | 151_Q | 1.408 | 1.00 | |
| 116_G | 138_L | 1.395 | 0.99 | |
| 312_A | 316_A | 1.389 | 0.99 | |
| 91_A | 97_A | 1.376 | 0.99 | |
| 298_I | 310_L | 1.373 | 0.99 | |
| 275_H | 279_D | 1.368 | 0.99 | |
| 10_K | 13_D | 1.359 | 0.99 | |
| 272_I | 311_V | 1.353 | 0.99 | |
| 43_T | 49_V | 1.335 | 0.99 | |
| 258_R | 324_A | 1.335 | 0.99 | |
| 69_H | 73_S | 1.333 | 0.99 | |
| 187_P | 190_N | 1.33 | 0.99 | |
| 228_G | 231_I | 1.329 | 0.99 | |
| 63_F | 100_I | 1.324 | 0.99 | |
| 232_K | 353_S | 1.314 | 0.99 | |
| 16_L | 65_T | 1.312 | 0.99 | |
| 261_I | 309_I | 1.307 | 0.99 | |
| 290_V | 298_I | 1.307 | 0.99 | |
| 230_R | 353_S | 1.305 | 0.99 | |
| 268_R | 271_E | 1.3 | 0.99 | |
| 372_E | 378_S | 1.299 | 0.99 | |
| 247_L | 329_F | 1.281 | 0.99 | |
| 41_P | 45_A | 1.28 | 0.99 | |
| 156_L | 159_I | 1.279 | 0.99 | |
| 162_V | 194_N | 1.277 | 0.99 | |
| 48_D | 214_N | 1.277 | 0.99 | |
| 44_L | 69_H | 1.261 | 0.99 | |
| 277_A | 283_V | 1.26 | 0.99 | |
| 334_P | 340_Y | 1.258 | 0.99 | |
| 40_L | 44_L | 1.245 | 0.98 | |
| 206_R | 210_F | 1.24 | 0.98 | |
| 24_L | 61_M | 1.227 | 0.98 | |
| 146_I | 178_D | 1.219 | 0.98 | |
| 98_V | 102_A | 1.212 | 0.98 | |
| 84_Q | 158_A | 1.211 | 0.98 | |
| 98_V | 296_L | 1.209 | 0.98 | |
| 246_L | 249_T | 1.204 | 0.98 | |
| 62_A | 66_S | 1.203 | 0.98 | |
| 203_Y | 207_E | 1.202 | 0.98 | |
| 270_E | 287_T | 1.198 | 0.98 | |
| 330_N | 344_I | 1.189 | 0.98 | |
| 39_A | 51_G | 1.188 | 0.98 | |
| 260_I | 312_A | 1.18 | 0.98 | |
| 249_T | 253_E | 1.173 | 0.98 | |
| 231_I | 348_G | 1.167 | 0.97 | |
| 239_S | 242_E | 1.158 | 0.97 | |
| 243_K | 332_D | 1.156 | 0.97 | |
| 336_D | 339_D | 1.148 | 0.97 | |
| 22_E | 25_E | 1.139 | 0.97 | |
| 15_A | 21_V | 1.137 | 0.97 | |
| 146_I | 150_K | 1.131 | 0.97 | |
| 48_D | 213_M | 1.129 | 0.97 | |
| 274_G | 278_A | 1.12 | 0.96 | |
| 305_G | 308_D | 1.117 | 0.96 | |
| 244_M | 279_D | 1.114 | 0.96 | |
| 19_K | 22_E | 1.111 | 0.96 | |
| 261_I | 331_Y | 1.108 | 0.96 | |
| 100_I | 103_D | 1.099 | 0.96 | |
| 149_A | 185_R | 1.098 | 0.96 | |
| 63_F | 91_A | 1.097 | 0.96 | |
| 11_F | 32_C | 1.096 | 0.96 | |
| 140_G | 154_I | 1.095 | 0.96 | |
| 24_L | 29_F | 1.094 | 0.96 | |
| 94_R | 121_G | 1.094 | 0.96 | |
| 118_A | 138_L | 1.09 | 0.96 | |
| 167_A | 196_L | 1.088 | 0.96 | |
| 257_D | 326_T | 1.082 | 0.96 | |
| 248_Q | 252_E | 1.08 | 0.95 | |
| 294_K | 298_I | 1.066 | 0.95 | |
| 259_A | 329_F | 1.056 | 0.95 | |
| 128_L | 153_H | 1.056 | 0.95 | |
| 42_L | 219_I | 1.054 | 0.95 | |
| 42_L | 47_R | 1.054 | 0.95 | |
| 290_V | 294_K | 1.034 | 0.94 | |
| 71_L | 87_A | 1.028 | 0.94 | |
| 164_L | 170_M | 1.026 | 0.94 | |
| 247_L | 331_Y | 1.025 | 0.93 | |
| 286_L | 315_V | 1.025 | 0.93 | |
| 128_L | 132_E | 1.022 | 0.93 | |
| 286_L | 316_A | 1.016 | 0.93 | |
| 47_R | 215_N | 1.013 | 0.93 | |
| 181_W | 185_R | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2db3A | 4 | 0.9169 | 100 | 0.318 | Contact Map | 0.85 |
| 4c9bA | 1 | 0.905 | 100 | 0.326 | Contact Map | 0.785 |
| 3eiqA | 2 | 0.905 | 100 | 0.327 | Contact Map | 0.729 |
| 2j0sA | 1 | 0.905 | 100 | 0.328 | Contact Map | 0.796 |
| 2i4iA | 1 | 0.943 | 100 | 0.337 | Contact Map | 0.777 |
| 3fmpB | 2 | 0.9074 | 100 | 0.341 | Contact Map | 0.772 |
| 3sqwA | 1 | 0.9905 | 100 | 0.341 | Contact Map | 0.754 |
| 3i5xA | 1 | 0.9929 | 100 | 0.346 | Contact Map | 0.758 |
| 1fuuA | 2 | 0.905 | 100 | 0.35 | Contact Map | 0.739 |
| 1s2mA | 1 | 0.9216 | 100 | 0.353 | Contact Map | 0.805 |
Sequence Conservation (Image Generated using WebLogo v3)