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YEBC - Probable transcriptional regulatory protein YebC
UniProt: P0A8A0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11137
Length: 246 (246)
Sequences: 1624
Seq/Len: 6.60

YEBC
Paralog alert: 0.23 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YEBC YEEN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
135_S 203_S 3.877 1.00
112_E 226_C 3.695 1.00
67_N 71_A 3.592 1.00
13_R 17_Q 3.407 1.00
99_I 117_F 3.299 1.00
209_D 212_T 2.996 1.00
43_P 53_V 2.873 1.00
41_G 74_V 2.661 1.00
125_G 129_S 2.456 1.00
184_D 188_A 2.39 1.00
16_A 20_K 2.289 1.00
207_D 237_E 2.248 1.00
178_E 181_K 2.138 1.00
2_A 9_N 2.043 1.00
89_G 117_F 2.042 1.00
8_A 11_R 2.04 1.00
138_G 174_T 2.003 1.00
5_S 8_A 1.99 1.00
65_T 68_R 1.959 1.00
11_R 15_A 1.939 1.00
149_T 152_E 1.896 1.00
154_A 159_A 1.894 1.00
5_S 9_N 1.891 1.00
210_A 245_T 1.87 1.00
120_C 222_M 1.85 1.00
101_C 109_T 1.775 1.00
97_I 219_L 1.763 1.00
31_E 48_R 1.745 1.00
116_A 226_C 1.745 1.00
179_M 196_A 1.742 1.00
174_T 182_V 1.722 1.00
175_A 178_E 1.678 1.00
160_E 178_E 1.673 1.00
71_A 76_G 1.651 1.00
83_E 106_R 1.638 1.00
208_M 216_L 1.636 1.00
152_E 156_E 1.635 1.00
205_K 237_E 1.606 1.00
97_I 117_F 1.588 1.00
63_R 67_N 1.581 1.00
163_V 173_Y 1.576 1.00
28_I 59_N 1.558 0.99
90_Y 96_A 1.532 0.99
69_A 73_G 1.524 0.99
220_I 234_H 1.508 0.99
153_A 191_L 1.503 0.99
7_W 11_R 1.489 0.99
147_E 164_T 1.461 0.99
53_V 57_L 1.459 0.99
86_I 98_M 1.455 0.99
9_N 13_R 1.394 0.99
212_T 215_K 1.393 0.99
2_A 5_S 1.393 0.99
115_H 118_S 1.388 0.98
51_A 55_K 1.387 0.98
142_F 172_V 1.381 0.98
143_E 194_D 1.376 0.98
91_G 216_L 1.374 0.98
140_I 174_T 1.371 0.98
14_K 18_D 1.368 0.98
220_I 224_E 1.367 0.98
176_W 198_V 1.351 0.98
100_E 231_E 1.334 0.98
8_A 12_H 1.333 0.98
24_I 59_N 1.328 0.98
202_P 205_K 1.325 0.98
154_A 162_V 1.315 0.98
183_R 187_E 1.314 0.98
150_I 170_I 1.294 0.97
53_V 70_I 1.294 0.97
9_N 17_Q 1.292 0.97
140_I 179_M 1.288 0.97
36_A 74_V 1.277 0.97
25_F 61_M 1.255 0.97
57_L 62_T 1.248 0.96
180_G 184_D 1.247 0.96
62_T 65_T 1.244 0.96
2_A 8_A 1.241 0.96
139_V 199_S 1.236 0.96
61_M 65_T 1.216 0.96
86_I 100_E 1.201 0.95
93_G 212_T 1.2 0.95
57_L 63_R 1.186 0.95
85_I 101_C 1.186 0.95
185_A 188_A 1.182 0.95
77_D 80_A 1.175 0.95
160_E 175_A 1.171 0.94
139_V 171_D 1.169 0.94
124_L 127_D 1.169 0.94
147_E 151_M 1.164 0.94
208_M 212_T 1.152 0.94
120_C 218_R 1.147 0.94
30_R 38_L 1.144 0.93
238_I 243_A 1.14 0.93
153_A 189_A 1.14 0.93
34_T 102_L 1.139 0.93
4_H 7_W 1.122 0.93
207_D 239_S 1.122 0.93
42_D 45_A 1.121 0.93
115_H 119_K 1.109 0.92
157_A 185_A 1.102 0.92
139_V 201_I 1.101 0.92
144_K 168_G 1.092 0.91
11_R 17_Q 1.088 0.91
115_H 120_C 1.084 0.91
111_A 115_H 1.082 0.91
10_T 14_K 1.079 0.91
133_L 203_S 1.079 0.91
211_E 214_P 1.076 0.90
64_D 68_R 1.07 0.90
210_A 242_V 1.063 0.90
6_K 11_R 1.063 0.90
116_A 222_M 1.061 0.90
151_M 155_L 1.055 0.89
184_D 187_E 1.054 0.89
162_V 172_V 1.054 0.89
86_I 200_M 1.051 0.89
53_V 66_L 1.047 0.89
157_A 182_V 1.029 0.88
133_L 204_T 1.022 0.87
137_K 202_P 1.018 0.87
216_L 236_G 1.015 0.87
97_I 216_L 1.011 0.86
219_L 223_L 1.009 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1konA11100-0.027Contact Map0.681
1lfpA10.9959100-0.024Contact Map0.7
4f3qA10.9878100-0.017Contact Map0.684
1mw7A10.94311000.051Contact Map0.731
2lqjA10.333345.90.959Contact Map0.454
2lvwA20.349626.80.964Contact Map0.495
2jsxA10.333324.90.964Contact Map0.485
3l7pA60.317118.40.966Contact Map0.653
1zl0A20.37417.30.967Contact Map0.487
4eysA10.329316.90.967Contact Map0.483

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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