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OPENSEQ.org

YFIB - Putative lipoprotein YfiB
UniProt: P07021 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11152
Length: 160 (145)
Sequences: 1476
Seq/Len: 10.18

YFIB
Paralog alert: 0.57 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PAL YFIB YIAD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
57_A 64_L 5.391 1.00
59_N 100_Y 4.062 1.00
102_E 106_L 3.302 1.00
91_H 136_Y 3.262 1.00
139_A 146_G 3.143 1.00
141_N 146_G 2.82 1.00
72_Q 115_A 2.705 1.00
140_S 146_G 2.684 1.00
72_Q 119_G 2.671 1.00
71_I 115_A 2.615 1.00
61_Y 107_K 2.394 1.00
89_D 132_L 2.347 1.00
132_L 136_Y 2.342 1.00
103_G 107_K 2.319 1.00
95_Y 147_R 2.272 1.00
98_D 134_K 2.251 1.00
63_L 67_S 2.21 1.00
105_S 131_G 2.02 1.00
58_K 95_Y 1.993 1.00
57_A 60_D 1.967 1.00
100_Y 103_G 1.92 1.00
143_T 146_G 1.895 1.00
98_D 135_K 1.788 1.00
141_N 147_R 1.72 1.00
100_Y 134_K 1.638 1.00
93_D 101_N 1.619 1.00
86_A 127_L 1.588 1.00
88_M 113_A 1.585 1.00
63_L 115_A 1.549 1.00
106_L 110_N 1.439 1.00
115_A 119_G 1.414 1.00
76_A 79_A 1.372 0.99
89_D 136_Y 1.367 0.99
31_V 35_Q 1.323 0.99
117_A 127_L 1.282 0.99
89_D 130_Q 1.253 0.99
122_I 126_N 1.244 0.98
113_A 127_L 1.218 0.98
139_A 149_E 1.176 0.98
142_K 146_G 1.16 0.97
97_E 100_Y 1.16 0.97
79_A 123_P 1.159 0.97
122_I 127_L 1.143 0.97
58_K 100_Y 1.138 0.97
117_A 124_R 1.138 0.97
113_A 129_T 1.111 0.96
87_R 158_T 1.096 0.96
89_D 156_V 1.091 0.96
102_E 135_K 1.078 0.95
94_N 147_R 1.06 0.95
59_N 107_K 1.058 0.95
47_S 156_V 1.058 0.95
77_K 81_T 1.053 0.95
140_S 143_T 1.034 0.94
28_P 31_V 1.027 0.94
137_P 141_N 1.015 0.93
113_A 117_A 1.007 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ldtA10.9751000.27Contact Map0.374
2k1sA10.84381000.312Contact Map0.566
2l26A10.99381000.321Contact Map0.283
2hqsH40.70631000.329Contact Map0.755
1r1mA10.76251000.33Contact Map0.539
2zf8A10.88121000.332Contact Map0.441
3s06A20.85621000.333Contact Map0.577
3s0yA20.95631000.333Contact Map0.592
4b62A10.88121000.34Contact Map0.638
3khnA20.93751000.349Contact Map0.703

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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