| UniProt: | P05523 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10329 | ||
| Length: | 269 (269) | ||
| Sequences: | 2217 | ||
| Seq/Len: | 8.24 |
| FPG
Paralog alert: 0.31 [within 20: 0.00] - ratio of genomes with paralogs Cluster includes: END8 FPG |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 185_R | 194_E | 3.97 | 1.00 | |
| 53_Q | 62_E | 3.605 | 1.00 | |
| 251_I | 262_F | 3.41 | 1.00 | |
| 154_I | 181_I | 3.34 | 1.00 | |
| 167_V | 172_A | 2.947 | 1.00 | |
| 191_S | 194_E | 2.778 | 1.00 | |
| 21_A | 99_N | 2.676 | 1.00 | |
| 140_G | 199_A | 2.64 | 1.00 | |
| 178_A | 208_R | 2.574 | 1.00 | |
| 60_L | 67_W | 2.5 | 1.00 | |
| 15_E | 19_V | 2.398 | 1.00 | |
| 215_T | 234_L | 2.335 | 1.00 | |
| 147_C | 157_W | 2.306 | 1.00 | |
| 151_K | 188_S | 2.229 | 1.00 | |
| 157_W | 187_A | 2.159 | 1.00 | |
| 249_T | 265_R | 2.134 | 1.00 | |
| 190_L | 194_E | 2.064 | 1.00 | |
| 235_Q | 245_R | 2.04 | 1.00 | |
| 27_V | 96_V | 2.037 | 1.00 | |
| 198_L | 202_I | 2.007 | 1.00 | |
| 11_R | 59_L | 1.992 | 1.00 | |
| 239_R | 245_R | 1.983 | 1.00 | |
| 157_W | 163_L | 1.946 | 1.00 | |
| 25_H | 96_V | 1.884 | 1.00 | |
| 70_I | 114_W | 1.851 | 1.00 | |
| 47_Q | 65_E | 1.812 | 1.00 | |
| 185_R | 189_S | 1.806 | 1.00 | |
| 167_V | 202_I | 1.76 | 1.00 | |
| 179_A | 201_V | 1.751 | 1.00 | |
| 128_H | 162_K | 1.748 | 1.00 | |
| 93_V | 114_W | 1.739 | 1.00 | |
| 25_H | 45_S | 1.726 | 1.00 | |
| 21_A | 98_S | 1.719 | 1.00 | |
| 194_E | 197_L | 1.717 | 1.00 | |
| 178_A | 201_V | 1.704 | 1.00 | |
| 30_N | 110_R | 1.702 | 1.00 | |
| 152_T | 160_D | 1.701 | 1.00 | |
| 23_I | 63_L | 1.689 | 1.00 | |
| 254_T | 263_Y | 1.688 | 1.00 | |
| 70_I | 78_L | 1.683 | 1.00 | |
| 140_G | 143_L | 1.668 | 1.00 | |
| 253_A | 260_A | 1.662 | 1.00 | |
| 22_T | 98_S | 1.647 | 1.00 | |
| 11_R | 15_E | 1.644 | 1.00 | |
| 239_R | 242_E | 1.634 | 1.00 | |
| 152_T | 157_W | 1.613 | 1.00 | |
| 184_D | 254_T | 1.601 | 1.00 | |
| 47_Q | 64_P | 1.592 | 1.00 | |
| 144_H | 192_L | 1.568 | 1.00 | |
| 177_F | 246_V | 1.567 | 1.00 | |
| 181_I | 198_L | 1.552 | 1.00 | |
| 264_C | 267_C | 1.539 | 1.00 | |
| 140_G | 196_E | 1.529 | 1.00 | |
| 24_L | 98_S | 1.523 | 1.00 | |
| 167_V | 175_S | 1.522 | 1.00 | |
| 147_C | 154_I | 1.514 | 1.00 | |
| 141_E | 192_L | 1.513 | 1.00 | |
| 178_A | 205_V | 1.509 | 1.00 | |
| 143_L | 199_A | 1.494 | 1.00 | |
| 142_Y | 146_K | 1.491 | 1.00 | |
| 252_V | 265_R | 1.487 | 1.00 | |
| 173_S | 262_F | 1.462 | 0.99 | |
| 192_L | 196_E | 1.455 | 0.99 | |
| 35_W | 113_A | 1.45 | 0.99 | |
| 144_H | 195_C | 1.443 | 0.99 | |
| 201_V | 204_A | 1.438 | 0.99 | |
| 15_E | 51_S | 1.438 | 0.99 | |
| 240_K | 262_F | 1.424 | 0.99 | |
| 50_L | 64_P | 1.42 | 0.99 | |
| 8_E | 11_R | 1.416 | 0.99 | |
| 244_C | 264_C | 1.407 | 0.99 | |
| 139_N | 142_Y | 1.404 | 0.99 | |
| 55_R | 132_E | 1.404 | 0.99 | |
| 147_C | 195_C | 1.403 | 0.99 | |
| 244_C | 247_C | 1.377 | 0.99 | |
| 149_K | 188_S | 1.372 | 0.99 | |
| 8_E | 54_R | 1.367 | 0.99 | |
| 153_A | 156_P | 1.358 | 0.99 | |
| 142_Y | 145_Q | 1.355 | 0.99 | |
| 236_V | 251_I | 1.35 | 0.99 | |
| 178_A | 235_Q | 1.344 | 0.99 | |
| 62_E | 67_W | 1.334 | 0.99 | |
| 186_L | 189_S | 1.332 | 0.99 | |
| 63_L | 68_I | 1.319 | 0.99 | |
| 91_D | 106_T | 1.309 | 0.98 | |
| 141_E | 145_Q | 1.304 | 0.98 | |
| 138_F | 164_V | 1.282 | 0.98 | |
| 182_H | 263_Y | 1.271 | 0.98 | |
| 131_P | 135_S | 1.271 | 0.98 | |
| 133_P | 138_F | 1.266 | 0.98 | |
| 243_P | 249_T | 1.261 | 0.98 | |
| 28_V | 93_V | 1.247 | 0.98 | |
| 8_E | 12_R | 1.234 | 0.98 | |
| 247_C | 264_C | 1.226 | 0.97 | |
| 244_C | 267_C | 1.221 | 0.97 | |
| 18_L | 49_V | 1.216 | 0.97 | |
| 175_S | 202_I | 1.21 | 0.97 | |
| 21_A | 101_K | 1.205 | 0.97 | |
| 178_A | 204_A | 1.196 | 0.97 | |
| 215_T | 231_A | 1.185 | 0.97 | |
| 52_V | 61_L | 1.171 | 0.96 | |
| 22_T | 48_P | 1.157 | 0.96 | |
| 156_P | 257_A | 1.155 | 0.96 | |
| 41_I | 114_W | 1.142 | 0.96 | |
| 18_L | 97_M | 1.142 | 0.96 | |
| 164_V | 167_V | 1.136 | 0.95 | |
| 208_R | 233_E | 1.132 | 0.95 | |
| 150_K | 157_W | 1.131 | 0.95 | |
| 49_V | 63_L | 1.127 | 0.95 | |
| 29_R | 94_D | 1.126 | 0.95 | |
| 180_G | 246_V | 1.109 | 0.95 | |
| 256_H | 261_T | 1.107 | 0.95 | |
| 77_S | 108_P | 1.104 | 0.94 | |
| 247_C | 267_C | 1.103 | 0.94 | |
| 177_F | 235_Q | 1.097 | 0.94 | |
| 49_V | 61_L | 1.093 | 0.94 | |
| 182_H | 269_K | 1.091 | 0.94 | |
| 48_P | 64_P | 1.091 | 0.94 | |
| 131_P | 164_V | 1.082 | 0.94 | |
| 94_D | 102_V | 1.081 | 0.94 | |
| 135_S | 203_K | 1.078 | 0.93 | |
| 252_V | 263_Y | 1.078 | 0.93 | |
| 155_K | 172_A | 1.067 | 0.93 | |
| 78_L | 105_Y | 1.065 | 0.93 | |
| 214_G | 228_G | 1.063 | 0.93 | |
| 135_S | 138_F | 1.059 | 0.93 | |
| 243_P | 250_P | 1.05 | 0.92 | |
| 158_L | 202_I | 1.047 | 0.92 | |
| 4_L | 8_E | 1.044 | 0.92 | |
| 200_R | 204_A | 1.044 | 0.92 | |
| 51_S | 62_E | 1.043 | 0.92 | |
| 175_S | 198_L | 1.033 | 0.91 | |
| 41_I | 70_I | 1.027 | 0.91 | |
| 92_H | 110_R | 1.025 | 0.91 | |
| 240_K | 253_A | 1.016 | 0.90 | |
| 222_Q | 226_K | 1.008 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1k82A | 4 | 0.9963 | 100 | 0.038 | Contact Map | 0.871 |
| 3u6pA | 1 | 0.9963 | 100 | 0.042 | Contact Map | 0.869 |
| 2xzfA | 1 | 0.9888 | 100 | 0.045 | Contact Map | 0.832 |
| 3twlA | 1 | 0.9591 | 100 | 0.085 | Contact Map | 0.702 |
| 1ee8A | 2 | 0.9591 | 100 | 0.12 | Contact Map | 0.903 |
| 3vk8A | 2 | 0.9442 | 100 | 0.126 | Contact Map | 0.743 |
| 1k3xA | 1 | 0.9405 | 100 | 0.141 | Contact Map | 0.745 |
| 4mb7A | 1 | 0.8959 | 100 | 0.188 | Contact Map | 0.727 |
| 1tdhA | 1 | 0.9368 | 100 | 0.242 | Contact Map | 0.52 |
| 3w0fA | 1 | 0.9294 | 100 | 0.253 | Contact Map | 0.701 |
Sequence Conservation (Image Generated using WebLogo v3)