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OPENSEQ.org

DXR - UPPS
UniProt: P45568 - P60472
Length: 651
Sequences: 778
Seq/Len: 1.25
I_Prob: 0.00

DXR - 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: DXR
UPPS - Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: UPPS
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
34_V 68_Y 1.04 0.00
299_F 44_K 1.01 0.00
232_Y 39_R 0.93 0.00
40_T 236_F 0.92 0.00
274_P 216_F 0.91 0.00
16_S 72_S 0.90 0.00
114_I 192_V 0.88 0.00
268_L 57_A 0.88 0.00
121_L 72_S 0.86 0.00
232_Y 29_G 0.85 0.00
225_M 134_N 0.84 0.00
122_L 147_G 0.84 0.00
185_G 38_I 0.83 0.00
114_I 68_Y 0.80 0.00
198_L 69_A 0.80 0.00
284_M 190_D 0.80 0.00
206_A 198_E 0.80 0.00
9_S 92_A 0.79 0.00
90_A 212_A 0.79 0.00
34_V 23_I 0.79 0.00
19_D 189_V 0.78 0.00
255_V 236_F 0.78 0.00
337_A 85_L 0.77 0.00
244_S 171_Q 0.77 0.00
189_P 89_F 0.77 0.00
68_M 21_V 0.76 0.00
21_V 50_V 0.76 0.00
99_A 72_S 0.76 0.00
2_K 34_K 0.75 0.00
135_F 143_A 0.75 0.00
236_R 29_G 0.75 0.00
375_V 60_N 0.75 0.00
310_P 66_T 0.75 0.00
248_V 82_V 0.74 0.00
94_V 236_F 0.74 0.00
121_L 150_D 0.73 0.00
192_E 45_A 0.73 0.00
232_Y 174_E 0.73 0.00
85_A 68_Y 0.72 0.00
382_D 51_R 0.72 0.00
332_T 140_N 0.72 0.00
294_V 68_Y 0.72 0.00
130_T 245_G 0.71 0.00
120_I 83_S 0.70 0.00
383_A 169_P 0.70 0.00
37_K 215_Y 0.70 0.00
205_Q 188_P 0.70 0.00
111_L 139_L 0.70 0.00
199_A 163_Q 0.70 0.00
121_L 149_W 0.70 0.00
299_F 108_R 0.69 0.00
366_K 236_F 0.69 0.00
216_R 196_G 0.69 0.00
87_D 21_V 0.69 0.00
256_I 124_I 0.69 0.00
269_A 66_T 0.69 0.00
30_V 135_T 0.69 0.00
317_C 100_L 0.69 0.00
208_R 151_I 0.69 0.00
309_A 152_V 0.68 0.00
379_L 56_F 0.68 0.00
108_L 156_R 0.68 0.00
325_F 64_A 0.68 0.00
281_A 72_S 0.68 0.00
364_L 127_S 0.67 0.00
244_S 238_N 0.67 0.00
236_R 80_Q 0.66 0.00
66_K 62_I 0.66 0.00
303_S 97_V 0.66 0.00
251_H 25_M 0.66 0.00
358_A 229_F 0.66 0.00
357_A 89_F 0.66 0.00
203_P 243_F 0.66 0.00
317_C 93_L 0.65 0.00
22_R 132_A 0.65 0.00
28_F 55_S 0.65 0.00
236_R 99_S 0.65 0.00
159_S 84_A 0.65 0.00
267_V 87_E 0.65 0.00
191_R 199_H 0.65 0.00
207_C 182_C 0.65 0.00
50_S 133_G 0.64 0.00
295_K 62_I 0.64 0.00
226_M 78_P 0.64 0.00
364_L 54_V 0.64 0.00
121_L 183_M 0.64 0.00
259_M 189_V 0.63 0.00
185_G 55_S 0.63 0.00
265_G 54_V 0.63 0.00
253_Q 47_A 0.63 0.00
159_S 45_A 0.63 0.00
205_Q 231_G 0.63 0.00
267_V 93_L 0.63 0.00
253_Q 205_L 0.63 0.00
157_F 66_T 0.63 0.00
368_D 106_R 0.63 0.00
226_M 47_A 0.63 0.00
278_T 120_L 0.63 0.00
366_K 59_N 0.63 0.00
388_V 173_D 0.62 0.00
274_P 220_L 0.62 0.00
194_P 21_V 0.62 0.00
335_L 240_E 0.62 0.00
249_L 123_R 0.62 0.00
140_K 163_Q 0.62 0.00
34_V 57_A 0.62 0.00
283_T 97_V 0.62 0.00
65_L 110_I 0.62 0.00
161_P 150_D 0.62 0.00
317_C 209_I 0.62 0.00
96_Q 104_N 0.62 0.00
193_T 76_N 0.62 0.00
322_M 29_G 0.61 0.00
142_S 173_D 0.61 0.00
387_E 132_A 0.61 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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