| UniProt: | P60472 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13329 | ||
| Length: | 253 (231) | ||
| Sequences: | 2376 | ||
| Seq/Len: | 10.29 |
| UPPS
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 19_R | 63_E | 3.69 | 1.00 | |
| 50_V | 67_L | 3.56 | 1.00 | |
| 161_K | 166_N | 3.188 | 1.00 | |
| 161_K | 180_H | 3.116 | 1.00 | |
| 104_N | 136_G | 2.997 | 1.00 | |
| 129_A | 132_A | 2.876 | 1.00 | |
| 219_V | 228_D | 2.566 | 1.00 | |
| 192_V | 209_I | 2.501 | 1.00 | |
| 189_V | 212_A | 2.45 | 1.00 | |
| 90_V | 119_R | 2.407 | 1.00 | |
| 104_N | 135_T | 2.354 | 1.00 | |
| 228_D | 231_G | 2.338 | 1.00 | |
| 101_H | 130_L | 2.203 | 1.00 | |
| 112_D | 153_Q | 2.193 | 1.00 | |
| 152_V | 177_L | 2.191 | 1.00 | |
| 37_K | 41_F | 2.181 | 1.00 | |
| 94_D | 123_R | 2.155 | 1.00 | |
| 29_G | 39_R | 2.131 | 1.00 | |
| 59_N | 226_E | 2.066 | 1.00 | |
| 153_Q | 182_C | 2.049 | 1.00 | |
| 201_I | 209_I | 2.032 | 1.00 | |
| 56_F | 230_E | 2.025 | 1.00 | |
| 51_R | 96_E | 2.023 | 1.00 | |
| 149_W | 153_Q | 1.947 | 1.00 | |
| 121_Q | 125_R | 1.918 | 1.00 | |
| 58_A | 136_G | 1.913 | 1.00 | |
| 215_Y | 232_A | 1.909 | 1.00 | |
| 113_T | 128_E | 1.908 | 1.00 | |
| 113_T | 125_R | 1.905 | 1.00 | |
| 49_S | 52_R | 1.905 | 1.00 | |
| 40_A | 84_A | 1.868 | 1.00 | |
| 109_I | 124_I | 1.853 | 1.00 | |
| 34_K | 220_L | 1.827 | 1.00 | |
| 64_A | 140_N | 1.777 | 1.00 | |
| 118_S | 122_E | 1.752 | 1.00 | |
| 57_A | 229_F | 1.751 | 1.00 | |
| 79_A | 83_S | 1.736 | 1.00 | |
| 21_V | 229_F | 1.736 | 1.00 | |
| 41_F | 44_K | 1.724 | 1.00 | |
| 101_H | 134_N | 1.708 | 1.00 | |
| 149_W | 182_C | 1.693 | 1.00 | |
| 64_A | 186_L | 1.682 | 1.00 | |
| 155_V | 177_L | 1.671 | 1.00 | |
| 76_N | 245_G | 1.668 | 1.00 | |
| 215_Y | 235_A | 1.667 | 1.00 | |
| 157_Q | 180_H | 1.644 | 1.00 | |
| 168_Q | 171_Q | 1.623 | 1.00 | |
| 55_S | 103_H | 1.617 | 1.00 | |
| 64_A | 187_A | 1.611 | 1.00 | |
| 148_R | 188_P | 1.606 | 1.00 | |
| 150_D | 182_C | 1.584 | 1.00 | |
| 115_R | 144_N | 1.574 | 1.00 | |
| 159_A | 162_V | 1.542 | 1.00 | |
| 52_R | 226_E | 1.503 | 1.00 | |
| 225_D | 228_D | 1.502 | 1.00 | |
| 192_V | 212_A | 1.5 | 1.00 | |
| 64_A | 138_T | 1.496 | 1.00 | |
| 140_N | 186_L | 1.475 | 1.00 | |
| 23_I | 53_A | 1.426 | 1.00 | |
| 60_N | 230_E | 1.426 | 1.00 | |
| 125_R | 129_A | 1.416 | 1.00 | |
| 233_L | 237_A | 1.416 | 1.00 | |
| 70_F | 82_V | 1.403 | 0.99 | |
| 106_R | 138_T | 1.389 | 0.99 | |
| 122_E | 126_K | 1.386 | 0.99 | |
| 108_R | 138_T | 1.385 | 0.99 | |
| 113_T | 121_Q | 1.378 | 0.99 | |
| 104_N | 134_N | 1.367 | 0.99 | |
| 160_E | 164_Q | 1.366 | 0.99 | |
| 148_R | 174_E | 1.366 | 0.99 | |
| 240_E | 247_E | 1.359 | 0.99 | |
| 55_S | 99_S | 1.338 | 0.99 | |
| 45_A | 48_K | 1.329 | 0.99 | |
| 151_I | 155_V | 1.319 | 0.99 | |
| 44_K | 91_W | 1.301 | 0.99 | |
| 17_G | 62_I | 1.296 | 0.99 | |
| 60_N | 233_L | 1.291 | 0.99 | |
| 126_K | 130_L | 1.287 | 0.99 | |
| 38_I | 41_F | 1.275 | 0.99 | |
| 70_F | 75_W | 1.264 | 0.99 | |
| 162_V | 165_G | 1.26 | 0.99 | |
| 147_G | 206_L | 1.25 | 0.99 | |
| 66_T | 142_A | 1.249 | 0.99 | |
| 151_I | 177_L | 1.238 | 0.98 | |
| 158_L | 172_I | 1.231 | 0.98 | |
| 158_L | 176_M | 1.226 | 0.98 | |
| 235_A | 238_N | 1.222 | 0.98 | |
| 98_K | 102_R | 1.21 | 0.98 | |
| 116_F | 143_A | 1.202 | 0.98 | |
| 56_F | 59_N | 1.185 | 0.98 | |
| 66_T | 205_L | 1.18 | 0.98 | |
| 112_D | 149_W | 1.165 | 0.97 | |
| 21_V | 62_I | 1.161 | 0.97 | |
| 177_L | 180_H | 1.159 | 0.97 | |
| 191_L | 232_A | 1.159 | 0.97 | |
| 110_I | 142_A | 1.153 | 0.97 | |
| 49_S | 53_A | 1.153 | 0.97 | |
| 67_L | 139_L | 1.13 | 0.97 | |
| 158_L | 180_H | 1.126 | 0.97 | |
| 150_D | 153_Q | 1.123 | 0.97 | |
| 108_R | 185_E | 1.104 | 0.96 | |
| 163_Q | 169_P | 1.104 | 0.96 | |
| 234_N | 237_A | 1.1 | 0.96 | |
| 118_S | 121_Q | 1.086 | 0.96 | |
| 108_R | 128_E | 1.083 | 0.96 | |
| 22_A | 192_V | 1.039 | 0.94 | |
| 150_D | 208_Q | 1.035 | 0.94 | |
| 82_V | 86_M | 1.035 | 0.94 | |
| 97_V | 130_L | 1.034 | 0.94 | |
| 90_V | 120_L | 1.033 | 0.94 | |
| 109_I | 113_T | 1.027 | 0.94 | |
| 89_F | 143_A | 1.026 | 0.94 | |
| 94_D | 126_K | 1.021 | 0.93 | |
| 163_Q | 168_Q | 1.021 | 0.93 | |
| 105_V | 137_L | 1.014 | 0.93 | |
| 159_A | 172_I | 1.014 | 0.93 | |
| 173_D | 176_M | 1.009 | 0.93 | |
| 78_P | 246_T | 1.005 | 0.93 | |
| 167_L | 176_M | 1.005 | 0.93 | |
| 172_I | 176_M | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3sgvB | 2 | 1 | 100 | 0.067 | Contact Map | 0.8 |
| 2d2rA | 2 | 0.9605 | 100 | 0.107 | Contact Map | 0.828 |
| 1f75A | 2 | 0.9723 | 100 | 0.112 | Contact Map | 0.833 |
| 2vg3A | 4 | 0.9723 | 100 | 0.114 | Contact Map | 0.87 |
| 4h8eA | 1 | 0.9842 | 100 | 0.115 | Contact Map | 0.755 |
| 3ugsB | 2 | 0.8893 | 100 | 0.147 | Contact Map | 0.769 |
| 2vg0A | 2 | 0.8775 | 100 | 0.153 | Contact Map | 0.686 |
| 3qxbA | 4 | 0.9051 | 24 | 0.968 | Contact Map | 0.296 |
| 4kzkA | 1 | 0.6759 | 21.7 | 0.969 | Contact Map | 0.364 |
| 3c8fA | 1 | 0.5138 | 19.4 | 0.97 | Contact Map | 0.309 |
Sequence Conservation (Image Generated using WebLogo v3)