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OPENSEQ.org

PTPC1 - PTPD
UniProt: P42910 - P42911
Length: 530
Sequences: 635
Seq/Len: 1.25
I_Prob: 1.00

PTPC1 - N-acetylgalactosamine permease IIC component 1
Paralog alert: 0.85 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: PTNC PTPC1
PTPD - N-acetylgalactosamine permease IID component
Paralog alert: 0.75 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: PTND PTPD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
130_K 58_K 3.71 1.00
210_L 189_I 2.94 1.00
34_I 122_C 2.30 0.98
126_D 28_R 2.29 0.98
232_G 180_L 1.98 0.93
123_T 27_E 1.74 0.86
125_A 32_G 1.72 0.85
180_H 258_S 1.72 0.85
134_T 53_L 1.51 0.72
125_A 61_L 1.44 0.66
104_S 71_V 1.42 0.64
12_L 223_I 1.38 0.60
217_V 191_S 1.28 0.50
218_C 222_N 1.27 0.49
141_N 23_S 1.27 0.48
79_G 26_Y 1.25 0.46
228_V 187_G 1.25 0.46
138_S 39_L 1.20 0.40
56_L 127_S 1.18 0.39
184_V 258_S 1.18 0.39
129_A 61_L 1.17 0.37
135_A 179_I 1.17 0.37
129_A 57_M 1.15 0.35
217_V 195_I 1.15 0.35
129_A 54_S 1.12 0.32
167_M 90_T 1.12 0.32
179_T 81_M 1.10 0.31
10_L 179_I 1.10 0.30
199_R 236_L 1.10 0.30
184_V 263_L 1.10 0.30
132_A 53_L 1.09 0.30
161_Y 74_L 1.08 0.29
104_S 17_S 1.07 0.27
132_A 54_S 1.06 0.26
137_F 35_T 1.05 0.26
81_M 246_L 1.03 0.24
135_A 239_K 1.02 0.23
192_V 250_T 1.01 0.22
10_L 248_G 1.01 0.22
14_A 143_L 1.00 0.21
191_A 193_V 1.00 0.21
186_G 66_T 1.00 0.21
132_A 50_K 0.99 0.20
96_A 44_K 0.99 0.20
154_V 217_D 0.99 0.20
177_W 259_A 0.98 0.20
18_V 186_G 0.98 0.19
205_Q 175_R 0.96 0.18
234_G 52_G 0.96 0.18
198_L 229_T 0.96 0.18
156_A 24_F 0.96 0.18
32_R 115_L 0.95 0.17
69_G 151_W 0.95 0.17
42_A 48_D 0.95 0.17
51_L 42_L 0.94 0.17
179_T 198_V 0.94 0.17
51_L 131_L 0.94 0.17
187_G 180_L 0.94 0.16
29_F 115_L 0.93 0.16
167_M 167_R 0.92 0.15
188_I 254_S 0.92 0.15
71_Q 64_I 0.92 0.15
99_L 109_I 0.92 0.15
198_L 230_L 0.91 0.15
134_T 42_L 0.91 0.15
79_G 254_S 0.91 0.15
138_S 16_R 0.91 0.14
211_I 227_A 0.91 0.14
231_L 128_Q 0.91 0.14
209_Y 169_N 0.89 0.14
80_L 223_I 0.89 0.14
131_E 196_N 0.89 0.14
188_I 193_V 0.89 0.13
158_L 38_M 0.88 0.13
197_L 188_L 0.88 0.13
237_V 253_L 0.88 0.13
152_Y 24_F 0.88 0.13
14_A 81_M 0.87 0.12
227_P 248_G 0.87 0.12
168_Q 94_L 0.87 0.12
135_A 7_K 0.87 0.12
158_L 217_D 0.87 0.12
135_A 43_K 0.87 0.12
7_L 194_H 0.86 0.12
72_P 192_Y 0.86 0.12
38_T 131_L 0.86 0.12
55_G 126_A 0.86 0.12
199_R 22_A 0.85 0.11
87_W 64_I 0.85 0.11
209_Y 10_I 0.85 0.11
217_V 96_V 0.85 0.11
154_V 252_V 0.84 0.10
30_L 67_H 0.84 0.10
188_I 195_I 0.84 0.10
142_W 214_D 0.83 0.10
231_L 252_V 0.83 0.10
55_G 123_S 0.83 0.10
5_T 217_D 0.83 0.10
186_G 103_A 0.83 0.10
67_A 110_F 0.83 0.10
73_P 184_V 0.83 0.10
34_I 133_G 0.83 0.10
159_C 52_G 0.82 0.10
34_I 89_D 0.82 0.10
135_A 187_G 0.82 0.10
59_L 127_S 0.82 0.10
188_I 151_W 0.82 0.10
136_A 137_F 0.82 0.10
137_F 57_M 0.82 0.10
215_L 256_V 0.81 0.09
165_G 85_G 0.81 0.09
172_K 256_V 0.81 0.09
94_K 135_I 0.81 0.09
173_A 225_P 0.81 0.09
90_G 205_N 0.80 0.09
26_E 103_A 0.80 0.09
10_L 51_P 0.80 0.09
232_G 61_L 0.80 0.09
201_M 178_T 0.80 0.09
144_T 80_S 0.80 0.09
210_L 233_Y 0.80 0.09
217_V 187_G 0.80 0.09
163_A 124_S 0.79 0.09
97_I 140_V 0.79 0.08
10_L 56_A 0.79 0.08
170_L 161_K 0.79 0.08
14_A 260_F 0.79 0.08
232_G 178_T 0.79 0.08
80_L 220_F 0.79 0.08
19_L 243_P 0.79 0.08
192_V 232_M 0.79 0.08
162_L 105_I 0.79 0.08
243_A 172_M 0.78 0.08
227_P 187_G 0.78 0.08
97_I 58_K 0.78 0.08
169_A 256_V 0.78 0.08
211_I 226_M 0.78 0.08
234_G 227_A 0.78 0.08
18_V 119_A 0.78 0.08
150_S 256_V 0.78 0.08
218_C 105_I 0.78 0.08
68_G 98_L 0.78 0.08
209_Y 200_S 0.78 0.08
226_L 220_F 0.77 0.08
90_G 51_P 0.77 0.07
70_V 33_G 0.77 0.07
9_G 173_I 0.77 0.07
51_L 37_A 0.77 0.07
60_A 63_F 0.76 0.07
194_F 63_F 0.76 0.07
4_I 214_D 0.76 0.07
68_G 103_A 0.76 0.07
202_F 233_Y 0.76 0.07
80_L 38_M 0.76 0.07
42_A 12_R 0.76 0.07
52_I 139_A 0.76 0.07
98_G 164_D 0.76 0.07
109_Y 81_M 0.76 0.07
97_I 64_I 0.75 0.07
216_F 7_K 0.75 0.07
231_L 12_R 0.75 0.07
39_L 31_A 0.75 0.07
233_A 48_D 0.75 0.07
59_L 27_E 0.75 0.07
94_K 48_D 0.75 0.07
158_L 130_N 0.75 0.07
72_P 72_G 0.75 0.07
222_V 180_L 0.75 0.07
172_K 259_A 0.74 0.07
221_Q 200_S 0.74 0.07
46_D 203_I 0.74 0.07
134_T 43_K 0.74 0.07
229_A 77_L 0.74 0.07
182_F 190_A 0.74 0.07
149_A 247_I 0.74 0.07
35_I 74_L 0.74 0.06
184_V 250_T 0.74 0.06
18_V 226_M 0.74 0.06
162_L 173_I 0.74 0.06
168_Q 206_T 0.73 0.06
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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