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OPENSEQ.org

THIE - THIM
UniProt: P30137 - P76423
Length: 473
Sequences: 471
Seq/Len: 1.05
I_Prob: 0.00

THIE - Thiamine-phosphate synthase
Paralog alert: 0.31 [within 20: 0.06] - ratio of genomes with paralogs
Cluster includes: THIE
THIM - Hydroxyethylthiazole kinase
Paralog alert: 0.08 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: THIM
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
24_W 171_T 1.20 0.00
188_A 201_C 1.07 0.00
184_A 124_I 1.07 0.00
130_H 53_E 1.03 0.00
85_L 19_H 1.00 0.00
136_T 248_H 0.99 0.00
158_D 59_Q 0.94 0.00
31_A 223_S 0.94 0.00
203_L 206_V 0.93 0.00
51_D 40_T 0.91 0.00
131_V 142_R 0.90 0.00
56_I 129_S 0.90 0.00
100_A 129_S 0.89 0.00
129_G 203_L 0.88 0.00
179_G 66_A 0.88 0.00
31_A 82_M 0.88 0.00
108_S 100_P 0.87 0.00
195_W 165_G 0.87 0.00
61_R 177_V 0.87 0.00
63_N 211_C 0.87 0.00
145_G 242_P 0.87 0.00
193_A 20_Q 0.85 0.00
175_V 25_V 0.84 0.00
136_T 51_V 0.83 0.00
134_T 48_P 0.82 0.00
122_R 102_A 0.82 0.00
99_R 129_S 0.81 0.00
175_V 60_F 0.80 0.00
109_T 232_G 0.79 0.00
167_I 198_G 0.79 0.00
179_G 209_A 0.79 0.00
34_R 171_T 0.78 0.00
59_G 202_A 0.78 0.00
19_V 52_I 0.78 0.00
184_A 100_P 0.78 0.00
63_N 136_G 0.77 0.00
31_A 81_A 0.77 0.00
146_L 230_Q 0.76 0.00
66_L 18_F 0.76 0.00
130_H 128_A 0.76 0.00
197_L 122_A 0.75 0.00
190_T 246_V 0.75 0.00
132_F 19_H 0.75 0.00
88_E 171_T 0.74 0.00
190_T 206_V 0.74 0.00
188_A 24_L 0.74 0.00
87_Q 131_I 0.74 0.00
123_P 171_T 0.74 0.00
17_P 242_P 0.74 0.00
63_N 226_H 0.74 0.00
197_L 258_Q 0.74 0.00
144_Q 171_T 0.74 0.00
18_V 129_S 0.74 0.00
69_N 201_C 0.74 0.00
151_R 162_R 0.74 0.00
105_L 142_R 0.73 0.00
190_T 203_L 0.73 0.00
189_I 67_L 0.73 0.00
118_A 113_C 0.73 0.00
171_R 171_T 0.73 0.00
27_R 40_T 0.73 0.00
130_H 203_L 0.73 0.00
67_F 102_A 0.73 0.00
186_V 53_E 0.73 0.00
67_F 46_A 0.73 0.00
175_V 242_P 0.72 0.00
85_L 210_C 0.72 0.00
74_L 249_F 0.72 0.00
69_N 144_V 0.72 0.00
30_D 151_A 0.72 0.00
115_I 102_A 0.72 0.00
136_T 241_G 0.72 0.00
197_L 244_S 0.72 0.00
15_L 85_A 0.72 0.00
184_A 117_L 0.71 0.00
188_A 189_G 0.71 0.00
186_V 129_S 0.71 0.00
189_I 250_L 0.71 0.00
181_G 56_E 0.71 0.00
50_A 25_V 0.71 0.00
156_L 125_R 0.70 0.00
13_S 203_L 0.70 0.00
162_V 43_A 0.70 0.00
105_L 53_E 0.70 0.00
23_Q 240_E 0.70 0.00
163_A 79_A 0.70 0.00
147_E 146_T 0.69 0.00
63_N 218_L 0.69 0.00
74_L 34_Q 0.69 0.00
146_L 205_A 0.69 0.00
130_H 52_I 0.69 0.00
69_N 32_V 0.69 0.00
139_M 253_L 0.69 0.00
18_V 232_G 0.69 0.00
202_L 82_M 0.69 0.00
33_V 179_D 0.69 0.00
188_A 29_T 0.68 0.00
203_L 204_S 0.68 0.00
61_R 244_S 0.68 0.00
169_L 253_L 0.68 0.00
57_A 107_D 0.68 0.00
110_H 103_V 0.68 0.00
111_D 46_A 0.68 0.00
141_S 123_A 0.68 0.00
198_A 116_L 0.68 0.00
128_L 256_L 0.68 0.00
188_A 35_T 0.68 0.00
128_L 180_G 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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