| UniProt: | P30137 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11586 | ||
| Length: | 211 (196) | ||
| Sequences: | 2542 | ||
| Seq/Len: | 12.97 |
| THIE
Paralog alert: 0.31 [within 20: 0.06] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 136_T | 186_V | 3.378 | 1.00 | |
| 49_E | 77_K | 2.596 | 1.00 | |
| 196_R | 200_A | 2.465 | 1.00 | |
| 79_Q | 103_L | 2.404 | 1.00 | |
| 29_L | 64_A | 2.298 | 1.00 | |
| 56_I | 60_R | 2.173 | 1.00 | |
| 44_R | 47_E | 2.1 | 1.00 | |
| 172_A | 183_I | 2.08 | 1.00 | |
| 26_E | 30_D | 2.071 | 1.00 | |
| 194_D | 197_L | 2.057 | 1.00 | |
| 45_D | 71_Y | 2.053 | 1.00 | |
| 85_L | 95_L | 2.022 | 1.00 | |
| 26_E | 61_R | 2.02 | 1.00 | |
| 99_R | 103_L | 2.002 | 1.00 | |
| 29_L | 58_L | 1.959 | 1.00 | |
| 132_F | 171_R | 1.932 | 1.00 | |
| 59_G | 66_L | 1.911 | 1.00 | |
| 99_R | 105_L | 1.873 | 1.00 | |
| 117_V | 121_A | 1.839 | 1.00 | |
| 52_V | 78_H | 1.813 | 1.00 | |
| 31_A | 199_T | 1.737 | 1.00 | |
| 106_G | 125_Y | 1.681 | 1.00 | |
| 132_F | 174_A | 1.673 | 1.00 | |
| 153_V | 161_T | 1.627 | 1.00 | |
| 129_G | 164_I | 1.626 | 1.00 | |
| 87_Q | 114_E | 1.624 | 1.00 | |
| 17_P | 33_V | 1.62 | 1.00 | |
| 197_L | 201_Q | 1.606 | 1.00 | |
| 56_I | 59_G | 1.598 | 1.00 | |
| 29_L | 62_Y | 1.593 | 1.00 | |
| 17_P | 189_I | 1.582 | 1.00 | |
| 169_L | 201_Q | 1.576 | 1.00 | |
| 131_V | 149_L | 1.57 | 1.00 | |
| 30_D | 196_R | 1.55 | 1.00 | |
| 96_N | 100_A | 1.515 | 1.00 | |
| 153_V | 181_G | 1.51 | 1.00 | |
| 94_D | 97_A | 1.505 | 1.00 | |
| 17_P | 190_T | 1.45 | 1.00 | |
| 56_I | 81_Y | 1.432 | 1.00 | |
| 110_H | 114_E | 1.422 | 1.00 | |
| 119_L | 158_D | 1.413 | 1.00 | |
| 37_Q | 69_N | 1.412 | 1.00 | |
| 119_L | 159_Y | 1.402 | 0.99 | |
| 192_A | 198_A | 1.394 | 0.99 | |
| 49_E | 74_L | 1.383 | 0.99 | |
| 107_V | 123_P | 1.371 | 0.99 | |
| 116_D | 119_L | 1.357 | 0.99 | |
| 38_L | 48_V | 1.341 | 0.99 | |
| 60_R | 81_Y | 1.334 | 0.99 | |
| 49_E | 78_H | 1.315 | 0.99 | |
| 25_I | 55_A | 1.307 | 0.99 | |
| 86_G | 89_D | 1.295 | 0.99 | |
| 19_V | 36_L | 1.282 | 0.99 | |
| 26_E | 62_Y | 1.282 | 0.99 | |
| 27_R | 196_R | 1.275 | 0.99 | |
| 49_E | 53_V | 1.273 | 0.99 | |
| 72_W | 83_V | 1.271 | 0.99 | |
| 188_A | 198_A | 1.264 | 0.99 | |
| 54_A | 57_A | 1.261 | 0.99 | |
| 130_H | 143_P | 1.255 | 0.99 | |
| 112_D | 116_D | 1.253 | 0.99 | |
| 71_Y | 74_L | 1.245 | 0.98 | |
| 31_A | 196_R | 1.241 | 0.98 | |
| 48_V | 71_Y | 1.233 | 0.98 | |
| 188_A | 202_L | 1.222 | 0.98 | |
| 174_A | 177_A | 1.221 | 0.98 | |
| 173_P | 205_I | 1.217 | 0.98 | |
| 156_L | 159_Y | 1.216 | 0.98 | |
| 29_L | 59_G | 1.213 | 0.98 | |
| 40_I | 43_R | 1.212 | 0.98 | |
| 144_Q | 148_Q | 1.209 | 0.98 | |
| 169_L | 202_L | 1.205 | 0.98 | |
| 56_I | 66_L | 1.2 | 0.98 | |
| 91_Q | 94_D | 1.197 | 0.98 | |
| 131_V | 163_A | 1.196 | 0.98 | |
| 85_L | 107_V | 1.177 | 0.98 | |
| 50_A | 53_V | 1.176 | 0.98 | |
| 30_D | 62_Y | 1.174 | 0.98 | |
| 68_I | 80_A | 1.173 | 0.98 | |
| 34_R | 64_A | 1.149 | 0.97 | |
| 189_I | 199_T | 1.135 | 0.97 | |
| 135_Q | 187_S | 1.131 | 0.97 | |
| 115_I | 152_H | 1.125 | 0.97 | |
| 38_L | 51_D | 1.124 | 0.97 | |
| 16_Y | 37_Q | 1.117 | 0.96 | |
| 95_L | 99_R | 1.111 | 0.96 | |
| 33_V | 36_L | 1.107 | 0.96 | |
| 168_S | 171_R | 1.106 | 0.96 | |
| 92_A | 107_V | 1.088 | 0.96 | |
| 168_S | 188_A | 1.082 | 0.96 | |
| 168_S | 187_S | 1.075 | 0.95 | |
| 115_I | 156_L | 1.075 | 0.95 | |
| 150_A | 154_E | 1.064 | 0.95 | |
| 85_L | 105_L | 1.053 | 0.95 | |
| 149_L | 163_A | 1.052 | 0.95 | |
| 128_L | 161_T | 1.045 | 0.94 | |
| 176_I | 206_A | 1.039 | 0.94 | |
| 145_G | 148_Q | 1.027 | 0.94 | |
| 162_V | 182_S | 1.023 | 0.93 | |
| 113_M | 116_D | 1.015 | 0.93 | |
| 25_I | 36_L | 1.007 | 0.93 | |
| 45_D | 77_K | 1.006 | 0.93 | |
| 201_Q | 205_I | 1.005 | 0.93 | |
| 117_V | 120_A | 1.004 | 0.93 | |
| 35_T | 67_F | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3nl6A | 3 | 0.9858 | 100 | 0.338 | Contact Map | 0.855 |
| 1twdA | 2 | 0.9289 | 100 | 0.434 | Contact Map | 0.313 |
| 3o63A | 2 | 0.9858 | 100 | 0.453 | Contact Map | 0.814 |
| 3ceuA | 2 | 0.8957 | 100 | 0.457 | Contact Map | 0.542 |
| 1yadA | 4 | 0.9763 | 100 | 0.49 | Contact Map | 0.773 |
| 2tpsA | 2 | 0.9905 | 100 | 0.494 | Contact Map | 0.811 |
| 2yw3A | 6 | 0.9289 | 100 | 0.505 | Contact Map | 0.475 |
| 1xi3A | 2 | 0.9858 | 100 | 0.506 | Contact Map | 0.882 |
| 3iwpA | 12 | 0.9763 | 100 | 0.51 | Contact Map | 0.364 |
| 2bdqA | 2 | 0.9052 | 100 | 0.514 | Contact Map | 0.279 |
Sequence Conservation (Image Generated using WebLogo v3)