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OPENSEQ.org

LEU3 - LEUD
UniProt: P30125 - P30126
Length: 564
Sequences: 593
Seq/Len: 1.07
I_Prob: 0.00

LEU3 - 3-isopropylmalate dehydrogenase
Paralog alert: 0.65 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DMLA IDH LEU3
LEUD - 3-isopropylmalate dehydratase small subunit
Paralog alert: 0.14 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: LEUD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
95_L 95_D 1.15 0.00
317_D 194_A 1.11 0.00
161_A 47_W 1.07 0.00
93_G 95_D 1.07 0.00
302_I 192_Y 1.02 0.00
253_L 186_D 0.99 0.00
291_A 183_L 0.98 0.00
196_A 30_F 0.96 0.00
257_C 118_Q 0.95 0.00
75_S 32_Q 0.94 0.00
302_I 122_V 0.94 0.00
105_F 12_V 0.93 0.00
76_V 104_P 0.93 0.00
233_L 4_K 0.93 0.00
224_M 107_A 0.92 0.00
254_S 111_Y 0.92 0.00
21_T 150_A 0.92 0.00
11_P 114_S 0.92 0.00
30_V 101_V 0.91 0.00
256_E 47_W 0.90 0.00
239_Q 165_D 0.90 0.00
284_G 32_Q 0.90 0.00
42_H 146_V 0.89 0.00
71_V 166_A 0.87 0.00
323_E 186_D 0.87 0.00
258_A 169_R 0.86 0.00
74_G 110_F 0.86 0.00
11_P 76_A 0.85 0.00
19_V 45_N 0.85 0.00
30_V 24_A 0.84 0.00
134_I 13_V 0.84 0.00
302_I 30_F 0.84 0.00
295_I 150_A 0.83 0.00
111_A 132_L 0.82 0.00
294_N 150_A 0.82 0.00
187_R 146_V 0.81 0.00
258_A 43_L 0.81 0.00
173_E 30_F 0.81 0.00
189_K 73_I 0.80 0.00
75_S 77_R 0.80 0.00
275_Q 161_R 0.80 0.00
309_L 175_G 0.80 0.00
208_I 169_R 0.80 0.00
119_A 37_T 0.79 0.00
234_I 163_T 0.79 0.00
40_T 164_I 0.79 0.00
358_Y 100_V 0.79 0.00
324_R 150_A 0.78 0.00
328_R 143_H 0.78 0.00
187_R 106_F 0.77 0.00
244_L 123_K 0.76 0.00
84_L 24_A 0.76 0.00
273_N 47_W 0.76 0.00
179_A 59_P 0.76 0.00
29_A 69_Q 0.76 0.00
191_T 20_V 0.76 0.00
24_L 6_I 0.76 0.00
98_L 135_L 0.75 0.00
176_A 196_Q 0.75 0.00
128_A 149_E 0.75 0.00
339_L 156_G 0.75 0.00
246_S 24_A 0.75 0.00
272_L 132_L 0.74 0.00
189_K 7_K 0.74 0.00
122_P 15_L 0.74 0.00
212_I 8_H 0.73 0.00
100_K 90_P 0.73 0.00
317_D 191_A 0.73 0.00
207_E 95_D 0.73 0.00
316_D 96_Y 0.73 0.00
226_I 17_A 0.73 0.00
74_G 82_C 0.73 0.00
104_L 121_P 0.73 0.00
341_R 191_A 0.72 0.00
119_A 195_K 0.72 0.00
257_C 110_F 0.72 0.00
233_L 189_I 0.71 0.00
32_N 127_A 0.71 0.00
203_I 24_A 0.71 0.00
245_C 32_Q 0.71 0.00
254_S 105_S 0.71 0.00
318_A 3_E 0.71 0.00
341_R 194_A 0.71 0.00
273_N 10_G 0.70 0.00
1_M 171_C 0.70 0.00
353_D 150_A 0.70 0.00
211_E 149_E 0.70 0.00
30_V 143_H 0.70 0.00
222_A 173_M 0.70 0.00
19_V 49_F 0.70 0.00
180_F 95_D 0.70 0.00
307_L 121_P 0.69 0.00
213_A 143_H 0.69 0.00
215_E 51_D 0.69 0.00
22_Q 30_F 0.69 0.00
318_A 119_L 0.69 0.00
189_K 90_P 0.69 0.00
243_L 190_A 0.69 0.00
224_M 82_C 0.69 0.00
130_N 194_A 0.69 0.00
35_A 127_A 0.69 0.00
280_Y 124_L 0.68 0.00
218_D 127_A 0.68 0.00
119_A 72_S 0.68 0.00
166_V 192_Y 0.68 0.00
337_G 155_A 0.67 0.00
81_W 4_K 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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