| UniProt: | P30126 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11575 | ||
| Length: | 201 (194) | ||
| Sequences: | 1547 | ||
| Seq/Len: | 7.97 |
| LEUD
Paralog alert: 0.14 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 9_T | 145_D | 3.629 | 1.00 | |
| 53_K | 56_Q | 3.151 | 1.00 | |
| 151_Q | 169_R | 3.124 | 1.00 | |
| 125_S | 128_E | 2.8 | 1.00 | |
| 131_E | 158_K | 2.726 | 1.00 | |
| 167_F | 171_C | 2.638 | 1.00 | |
| 147_D | 150_A | 2.508 | 1.00 | |
| 24_A | 47_W | 2.368 | 1.00 | |
| 8_H | 72_S | 2.363 | 1.00 | |
| 14_P | 68_Y | 2.254 | 1.00 | |
| 50_L | 58_N | 2.195 | 1.00 | |
| 10_G | 72_S | 2.187 | 1.00 | |
| 50_L | 56_Q | 2.159 | 1.00 | |
| 170_H | 174_N | 2.118 | 1.00 | |
| 186_D | 190_A | 2.072 | 1.00 | |
| 149_E | 173_M | 2.019 | 1.00 | |
| 116_N | 178_S | 1.979 | 1.00 | |
| 126_D | 130_D | 1.942 | 1.00 | |
| 77_R | 133_F | 1.926 | 1.00 | |
| 114_S | 119_L | 1.905 | 1.00 | |
| 9_T | 143_H | 1.888 | 1.00 | |
| 76_A | 103_A | 1.878 | 1.00 | |
| 149_E | 169_R | 1.83 | 1.00 | |
| 33_K | 39_F | 1.771 | 1.00 | |
| 152_E | 159_T | 1.74 | 1.00 | |
| 100_V | 146_V | 1.711 | 1.00 | |
| 51_D | 54_G | 1.692 | 1.00 | |
| 11_L | 70_G | 1.676 | 1.00 | |
| 30_F | 42_H | 1.661 | 1.00 | |
| 57_P | 69_Q | 1.656 | 1.00 | |
| 185_H | 188_A | 1.655 | 1.00 | |
| 30_F | 45_N | 1.628 | 1.00 | |
| 151_Q | 164_I | 1.628 | 1.00 | |
| 42_H | 45_N | 1.627 | 1.00 | |
| 191_A | 194_A | 1.569 | 1.00 | |
| 50_L | 53_K | 1.559 | 1.00 | |
| 130_D | 134_A | 1.546 | 1.00 | |
| 102_I | 129_V | 1.533 | 1.00 | |
| 115_F | 164_I | 1.523 | 1.00 | |
| 29_Q | 45_N | 1.52 | 1.00 | |
| 151_Q | 166_A | 1.505 | 1.00 | |
| 102_I | 153_V | 1.456 | 0.99 | |
| 154_K | 159_T | 1.446 | 0.99 | |
| 67_Q | 70_G | 1.434 | 0.99 | |
| 13_V | 71_A | 1.421 | 0.99 | |
| 114_S | 121_P | 1.394 | 0.99 | |
| 170_H | 184_Q | 1.393 | 0.99 | |
| 78_E | 126_D | 1.384 | 0.99 | |
| 51_D | 56_Q | 1.347 | 0.99 | |
| 153_V | 160_Y | 1.344 | 0.99 | |
| 18_A | 78_E | 1.339 | 0.99 | |
| 90_P | 107_A | 1.338 | 0.99 | |
| 191_A | 195_K | 1.322 | 0.98 | |
| 41_A | 49_F | 1.303 | 0.98 | |
| 94_T | 119_L | 1.292 | 0.98 | |
| 187_D | 190_A | 1.289 | 0.98 | |
| 131_E | 160_Y | 1.286 | 0.98 | |
| 115_F | 121_P | 1.284 | 0.98 | |
| 7_K | 149_E | 1.277 | 0.98 | |
| 75_L | 136_V | 1.276 | 0.98 | |
| 2_A | 54_G | 1.267 | 0.98 | |
| 16_D | 133_F | 1.265 | 0.98 | |
| 128_E | 160_Y | 1.261 | 0.98 | |
| 75_L | 133_F | 1.245 | 0.98 | |
| 135_L | 157_E | 1.23 | 0.97 | |
| 21_D | 24_A | 1.213 | 0.97 | |
| 187_D | 191_A | 1.194 | 0.97 | |
| 16_D | 77_R | 1.193 | 0.97 | |
| 104_P | 129_V | 1.188 | 0.96 | |
| 50_L | 59_P | 1.188 | 0.96 | |
| 38_G | 41_A | 1.184 | 0.96 | |
| 122_V | 153_V | 1.182 | 0.96 | |
| 188_A | 191_A | 1.178 | 0.96 | |
| 5_F | 100_V | 1.173 | 0.96 | |
| 66_P | 69_Q | 1.169 | 0.96 | |
| 152_E | 161_R | 1.145 | 0.95 | |
| 124_L | 129_V | 1.143 | 0.95 | |
| 192_Y | 196_Q | 1.138 | 0.95 | |
| 8_H | 100_V | 1.134 | 0.95 | |
| 115_F | 168_R | 1.134 | 0.95 | |
| 150_A | 154_K | 1.131 | 0.95 | |
| 33_K | 42_H | 1.128 | 0.95 | |
| 110_F | 114_S | 1.127 | 0.95 | |
| 181_L | 184_Q | 1.125 | 0.95 | |
| 90_P | 119_L | 1.116 | 0.94 | |
| 43_L | 96_Y | 1.116 | 0.94 | |
| 164_I | 169_R | 1.115 | 0.94 | |
| 131_E | 134_A | 1.11 | 0.94 | |
| 135_L | 155_A | 1.085 | 0.93 | |
| 12_V | 136_V | 1.079 | 0.93 | |
| 18_A | 104_P | 1.074 | 0.93 | |
| 176_L | 180_G | 1.066 | 0.93 | |
| 31_L | 88_H | 1.063 | 0.92 | |
| 76_A | 101_V | 1.06 | 0.92 | |
| 170_H | 176_L | 1.053 | 0.92 | |
| 28_K | 46_D | 1.048 | 0.92 | |
| 39_F | 98_F | 1.037 | 0.91 | |
| 32_Q | 88_H | 1.033 | 0.91 | |
| 135_L | 142_I | 1.027 | 0.91 | |
| 5_F | 8_H | 1.023 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3q3wA | 2 | 0.995 | 100 | 0.134 | Contact Map | 0.8 |
| 2hcuA | 1 | 0.9801 | 100 | 0.15 | Contact Map | 0.804 |
| 3h5jA | 2 | 0.8408 | 100 | 0.253 | Contact Map | 0.817 |
| 3vbaA | 6 | 0.8507 | 100 | 0.377 | Contact Map | 0.658 |
| 1v7lA | 2 | 0.796 | 100 | 0.383 | Contact Map | 0.679 |
| 2pkpA | 1 | 0.8109 | 100 | 0.387 | Contact Map | 0.615 |
| 1l5jA | 2 | 0.9403 | 100 | 0.413 | Contact Map | 0.456 |
| 2b3yA | 2 | 0.8806 | 100 | 0.475 | Contact Map | 0.375 |
| 1c96A | 1 | 0.8856 | 100 | 0.49 | Contact Map | 0.42 |
| 1rduA | 1 | 0.5771 | 41.6 | 0.954 | Contact Map | 0.361 |
Sequence Conservation (Image Generated using WebLogo v3)