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OPENSEQ.org

NUOA - NUOK
UniProt: P0AFC3 - P0AFE4
Length: 247
Sequences: 697
Seq/Len: 3.18
I_Prob: 0.99

NUOA - NADH-quinone oxidoreductase subunit A
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: NUOA
NUOK - NADH-quinone oxidoreductase subunit K
Paralog alert: 0.08 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: NUOK
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3rkoAE:KGContact Map
4he8AB:KEContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
84_Y 67_S 2.11 0.99
80_V 66_I 2.00 0.98
66_A 50_G 1.51 0.90
13_H 76_G 1.36 0.82
21_I 41_A 1.35 0.82
54_I 40_N 1.35 0.82
69_Y 73_A 1.31 0.79
55_D 11_A 1.29 0.77
14_W 17_L 1.28 0.77
26_L 34_G 1.25 0.75
19_F 32_L 1.23 0.72
74_F 34_G 1.21 0.71
84_Y 41_A 1.19 0.69
66_A 14_L 1.18 0.68
109_V 16_V 1.15 0.65
112_A 76_G 1.14 0.64
98_V 62_Y 1.14 0.64
92_I 29_L 1.14 0.64
73_M 23_V 1.12 0.62
122_A 21_G 1.12 0.62
77_I 20_T 1.12 0.62
25_G 84_H 1.11 0.61
25_G 44_L 1.08 0.57
26_L 89_N 1.08 0.57
29_L 38_M 1.07 0.57
58_G 18_G 1.07 0.57
110_L 79_L 1.07 0.56
39_G 10_L 1.05 0.54
83_L 84_H 1.04 0.54
118_V 92_I 1.03 0.52
37_L 14_L 1.03 0.51
22_V 63_I 1.02 0.50
86_F 34_G 1.01 0.50
21_I 73_A 1.01 0.50
87_A 37_I 0.99 0.47
50_F 56_T 0.99 0.47
11_A 9_I 0.98 0.46
107_I 19_L 0.97 0.45
80_V 67_S 0.96 0.44
96_G 89_N 0.96 0.43
93_R 3_P 0.96 0.43
17_A 85_R 0.94 0.42
31_L 58_G 0.94 0.41
57_V 45_A 0.92 0.39
37_L 32_L 0.92 0.38
109_V 46_F 0.91 0.38
63_R 84_H 0.91 0.38
20_L 96_S 0.91 0.38
114_L 81_L 0.91 0.38
65_S 66_I 0.90 0.36
39_G 79_L 0.90 0.36
50_F 33_I 0.90 0.36
16_F 41_A 0.90 0.36
121_G 92_I 0.89 0.35
32_V 19_L 0.88 0.34
125_W 70_A 0.88 0.34
117_L 44_L 0.88 0.34
24_I 5_Q 0.88 0.34
103_A 28_L 0.88 0.34
68_F 98_M 0.88 0.34
34_G 83_L 0.88 0.33
90_T 68_L 0.87 0.33
123_L 71_A 0.87 0.33
11_A 65_A 0.86 0.32
19_F 79_L 0.86 0.32
67_K 33_I 0.86 0.32
19_F 46_F 0.86 0.32
74_F 21_G 0.86 0.31
109_V 100_G 0.86 0.31
106_F 25_R 0.85 0.31
82_A 26_R 0.85 0.31
65_S 40_N 0.85 0.30
44_R 17_L 0.85 0.30
115_V 91_N 0.84 0.30
37_L 62_Y 0.84 0.30
67_K 79_L 0.84 0.30
23_A 51_S 0.84 0.29
72_A 10_L 0.83 0.28
15_A 39_I 0.83 0.28
24_I 97_E 0.82 0.27
51_E 69_A 0.82 0.27
83_L 75_I 0.82 0.27
35_W 87_R 0.81 0.26
50_F 47_V 0.81 0.26
22_V 5_Q 0.81 0.26
49_P 47_V 0.80 0.26
105_I 33_I 0.80 0.26
19_F 66_I 0.80 0.25
34_G 20_T 0.80 0.25
114_L 4_L 0.80 0.25
36_F 21_G 0.80 0.25
23_A 35_L 0.79 0.24
109_V 20_T 0.79 0.24
77_I 69_A 0.79 0.24
33_G 16_V 0.79 0.24
38_G 54_G 0.78 0.23
36_F 3_P 0.78 0.23
95_S 41_A 0.78 0.23
105_I 80_L 0.78 0.23
100_F 86_R 0.78 0.23
125_W 59_Q 0.78 0.23
108_F 29_L 0.78 0.23
91_S 29_L 0.78 0.23
62_L 10_L 0.77 0.23
16_F 34_G 0.77 0.23
34_G 33_I 0.77 0.22
67_K 73_A 0.77 0.22
94_E 93_D 0.76 0.22
67_K 49_A 0.76 0.22
102_E 11_A 0.76 0.21
90_T 98_M 0.76 0.21
113_G 74_S 0.76 0.21
69_Y 8_L 0.75 0.21
114_L 55_Q 0.75 0.20
123_L 27_N 0.75 0.20
27_C 62_Y 0.75 0.20
97_W 54_G 0.75 0.20
100_F 19_L 0.75 0.20
35_W 95_V 0.75 0.20
80_V 40_N 0.74 0.20
117_L 64_L 0.74 0.20
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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