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OPENSEQ.org
TRPA - TRPE
UniProt: P0A877 - P00895
Length: 788
Sequences: 632
Seq/Len: 0.83
I_Prob: 0.01
TRPA - Tryptophan synthase alpha chain
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: TRPA 		TRPE - Anthranilate synthase component 1
Paralog alert: 0.40 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PABB TRPE
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
54_F 280_A 1.50 0.01
232_I 262_F 1.39 0.01
258_F 298_D 1.36 0.01
58_L 239_N 1.34 0.00
54_F 375_R 1.26 0.00
59_A 329_T 1.23 0.00
151_I 390_V 1.22 0.00
154_C 250_R 1.21 0.00
47_A 172_D 1.19 0.00
48_L 349_E 1.13 0.00
204_N 369_A 1.12 0.00
178_S 501_N 1.09 0.00
121_V 264_V 1.09 0.00
36_I 37_L 1.07 0.00
128_V 377_C 1.06 0.00
167_A 387_L 1.05 0.00
28_P 394_S 1.04 0.00
43_A 329_T 1.04 0.00
255_L 161_L 1.04 0.00
117_Q 276_S 1.03 0.00
50_L 306_A 1.02 0.00
207_P 393_Y 1.02 0.00
37_I 393_Y 1.01 0.00
59_A 396_V 1.00 0.00
252_L 245_F 0.99 0.00
233_S 486_V 0.99 0.00
77_T 439_A 0.98 0.00
108_N 266_P 0.98 0.00
50_L 300_D 0.98 0.00
54_F 239_N 0.97 0.00
233_S 294_F 0.97 0.00
123_V 471_A 0.97 0.00
48_L 165_S 0.96 0.00
100_L 407_L 0.96 0.00
232_I 173_F 0.96 0.00
249_E 393_Y 0.95 0.00
139_F 437_L 0.95 0.00
28_P 466_I 0.94 0.00
22_F 128_R 0.94 0.00
100_L 391_D 0.93 0.00
166_I 440_E 0.93 0.00
117_Q 182_M 0.93 0.00
261_P 491_V 0.93 0.00
76_V 48_D 0.92 0.00
237_I 376_I 0.92 0.00
63_T 447_G 0.92 0.00
48_L 173_F 0.92 0.00
264_A 409_H 0.92 0.00
19_F 324_Y 0.92 0.00
151_I 241_S 0.92 0.00
158_A 268_R 0.91 0.00
156_P 394_S 0.91 0.00
232_I 324_Y 0.90 0.00
208_P 303_L 0.90 0.00
168_S 406_E 0.89 0.00
101_M 278_L 0.89 0.00
232_I 359_L 0.89 0.00
217_P 170_C 0.89 0.00
232_I 193_I 0.89 0.00
129_A 311_S 0.88 0.00
232_I 391_D 0.88 0.00
28_P 421_M 0.88 0.00
242_E 300_D 0.88 0.00
124_D 458_A 0.88 0.00
8_F 393_Y 0.88 0.00
128_V 230_S 0.88 0.00
22_F 59_L 0.88 0.00
182_V 415_H 0.87 0.00
10_Q 486_V 0.87 0.00
149_A 293_M 0.87 0.00
151_I 131_Q 0.87 0.00
21_P 293_M 0.87 0.00
109_K 496_A 0.87 0.00
166_I 436_Q 0.87 0.00
40_L 286_K 0.87 0.00
47_A 384_V 0.86 0.00
226_A 393_Y 0.86 0.00
58_L 465_C 0.86 0.00
66_N 456_F 0.86 0.00
106_V 56_D 0.86 0.00
152_F 465_C 0.86 0.00
127_L 369_A 0.86 0.00
155_P 304_F 0.86 0.00
105_L 181_L 0.86 0.00
29_G 35_T 0.85 0.00
88_I 177_L 0.85 0.00
176_L 310_S 0.85 0.00
200_L 45_S 0.85 0.00
148_V 406_E 0.84 0.00
101_M 22_T 0.84 0.00
99_L 322_E 0.84 0.00
127_L 454_G 0.84 0.00
123_V 513_A 0.84 0.00
155_P 311_S 0.84 0.00
124_D 304_F 0.84 0.00
134_E 321_I 0.84 0.00
155_P 134_L 0.83 0.00
154_C 369_A 0.83 0.00
219_Q 257_R 0.83 0.00
207_P 152_Y 0.83 0.00
20_V 510_I 0.83 0.00
260_Q 409_H 0.83 0.00
174_T 194_Q 0.83 0.00
45_A 499_T 0.82 0.00
67_A 494_S 0.82 0.00
24_T 134_L 0.82 0.00
238_V 471_A 0.82 0.00
153_I 499_T 0.82 0.00
204_N 152_Y 0.82 0.00
148_V 208_L 0.82 0.00
35_K 331_P 0.82 0.00
118_C 313_K 0.81 0.00
262_M 63_A 0.81 0.00
263_K 419_A 0.81 0.00
112_D 351_E 0.81 0.00
48_L 247_G 0.81 0.00
202_E 247_G 0.81 0.00
70_R 416_A 0.81 0.00
185_A 37_L 0.81 0.00
180_A 47_D 0.81 0.00
208_P 456_F 0.80 0.00
129_A 284_L 0.80 0.00
238_V 461_D 0.80 0.00
232_I 426_L 0.80 0.00
167_A 250_R 0.80 0.00
94_T 453_V 0.80 0.00
242_E 413_A 0.80 0.00
168_S 319_R 0.80 0.00
118_C 149_L 0.80 0.00
58_L 379_P 0.80 0.00
206_A 374_A 0.80 0.00
43_A 396_V 0.80 0.00
179_R 453_V 0.80 0.00
60_D 435_M 0.80 0.00
232_I 385_A 0.80 0.00
200_L 176_Y 0.79 0.00
257_V 337_D 0.79 0.00
116_A 235_R 0.79 0.00
124_D 416_A 0.79 0.00
189_A 417_Y 0.79 0.00
159_D 399_L 0.79 0.00
226_A 453_V 0.79 0.00
237_I 453_V 0.78 0.00
127_L 252_L 0.78 0.00
148_V 379_P 0.78 0.00
40_L 183_V 0.78 0.00
155_P 474_E 0.78 0.00
86_A 163_Q 0.78 0.00
4_Y 329_T 0.78 0.00
43_A 245_F 0.78 0.00
96_P 57_S 0.78 0.00
77_T 387_L 0.77 0.00
219_Q 405_G 0.77 0.00
98_G 377_C 0.77 0.00
58_L 322_E 0.77 0.00
212_F 452_A 0.77 0.00
31_E 373_L 0.77 0.00
38_D 253_Q 0.77 0.00
218_D 354_T 0.77 0.00
214_I 392_R 0.77 0.00
167_A 480_V 0.77 0.00
63_T 245_F 0.77 0.00
220_V 467_V 0.77 0.00
170_G 276_S 0.77 0.00
39_T 496_A 0.77 0.00
18_A 261_I 0.77 0.00
41_I 418_R 0.77 0.00
55_S 456_F 0.77 0.00
60_D 400_V 0.77 0.00
257_V 169_N 0.77 0.00
178_S 466_I 0.77 0.00
202_E 203_E 0.76 0.00
117_Q 53_L 0.76 0.00
48_L 146_F 0.76 0.00
99_L 457_T 0.76 0.00
38_D 25_F 0.76 0.00
19_F 421_M 0.76 0.00
156_P 465_C 0.76 0.00
260_Q 410_D 0.76 0.00
260_Q 318_S 0.76 0.00
54_F 262_F 0.76 0.00
193_L 453_V 0.76 0.00
112_D 346_S 0.76 0.00
52_I 303_L 0.76 0.00
204_N 438_I 0.76 0.00
118_C 269_R 0.76 0.00
97_I 323_I 0.75 0.00
212_F 329_T 0.75 0.00
135_E 437_L 0.75 0.00
85_L 444_R 0.75 0.00
174_T 301_F 0.75 0.00
103_A 470_S 0.75 0.00
18_A 414_L 0.75 0.00
106_V 140_E 0.75 0.00
148_V 23_A 0.75 0.00
161_D 461_D 0.75 0.00
223_A 194_Q 0.75 0.00
106_V 405_G 0.75 0.00
17_G 390_V 0.75 0.00
3_R 334_R 0.75 0.00
60_D 326_I 0.75 0.00
109_K 335_R 0.74 0.00
201_K 381_S 0.74 0.00
230_G 262_F 0.74 0.00
109_K 397_M 0.74 0.00
120_K 419_A 0.74 0.00
60_D 470_S 0.74 0.00
197_V 293_M 0.74 0.00
229_A 47_D 0.74 0.00
82_F 149_L 0.74 0.00
152_F 324_Y 0.74 0.00
45_A 403_V 0.74 0.00
200_L 414_L 0.74 0.00
154_C 456_F 0.74 0.00
262_M 280_A 0.74 0.00
52_I 60_R 0.74 0.00
115_Y 456_F 0.74 0.00
237_I 25_F 0.74 0.00
66_N 38_L 0.74 0.00
63_T 331_P 0.74 0.00
182_V 455_Y 0.74 0.00
219_Q 461_D 0.73 0.00
81_C 276_S 0.73 0.00
242_E 243_E 0.73 0.00
197_V 249_V 0.73 0.00
124_D 369_A 0.73 0.00
20_V 311_S 0.73 0.00
205_A 177_L 0.73 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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